• Exploration of Immunology

    eISSN: 2768-6655
    EiC: Dominique J. Charron, MD, PhD
    Adjunct-EiC: Reem Al-Daccak, PhD
    Frequency: Bimonthly
    APC: No Article Processing Charge
    Publishing Model: Open Access
    Peer Review Model: Single Blind
    Permanent Archive: Portico
    Indexing & Archiving: DOAJ, CAS, CNKI, J-Gate, Dimensions, ResearchGate, etc.
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    Articles
    Open Access
    Review
    Role of Vav1, a hematopoietic signal transduction molecule, as an adaptor protein in health and disease
    The growth and differentiation of normal cells are controlled by protein-tyrosine kinases, which serve as receptors for a wide variety of external signals. Small protein modules called Src homology  [...] Read more.
    Shulamit Katzav
    Published: April 28, 2023 Explor Immunol. 2023;3:158–173
    DOI: https://doi.org/10.37349/ei.2023.00095
    This article belongs to the special issue The Role of Adaptor Proteins in Lymphoid Cell Signaling
    View:153
    Download:22
    Times Cited: 0
    Open Access
    Perspective
    Localization in vesicles, clusters and supramolecular complexes as key elements of LAT function
    Linker for activation of T cells (LAT) is a central adaptor protein in proximal T cell activation. A key element of its adaptor function is the efficiency with which LAT interacts with its binding p [...] Read more.
    Laura E. McMillan, Christoph Wülfing
    Published: April 27, 2023 Explor Immunol. 2023;3:148–157
    DOI: https://doi.org/10.37349/ei.2023.00094
    This article belongs to the special issue The Role of Adaptor Proteins in Lymphoid Cell Signaling
    View:118
    Download:17
    Times Cited: 0
    Open Access
    Review
    Chemokine-targeted nanoparticles: stimulation of the immune system in cancer immunotherapy
    Surgery, chemotherapy, radiation therapy, and immunotherapy are potential therapeutic choices for many malignant and metastatic cancers. Despite adverse side effects and pain, surgery and chemothera [...] Read more.
    Ranjeet Singh ... Partha Pratim Manna
    Published: April 27, 2023 Explor Immunol. 2023;3:123–147
    DOI: https://doi.org/10.37349/ei.2023.00093
    This article belongs to the special issue Nanomaterials interaction with chemokines: perspectives for applied immunology
    View:243
    Download:19
    Times Cited: 0
    Open Access
    Review
    Mesenchymal stem cells—the master immunomodulators
    Mesenchymal stem/stromal cells (MSCs) are known as multipotent cells due to their ability to differentiate into various cell lineages of mesoderm origin. Recent developments in stem cell biology hav [...] Read more.
    Mehak Vohra, Sunil K. Arora
    Published: April 27, 2023 Explor Immunol. 2023;3:104–122
    DOI: https://doi.org/10.37349/ei.2023.00092
    This article belongs to the special issue Interplay of Stem Cells and Immunology in Regenerative Medicine
    View:165
    Download:15
    Times Cited: 0
    Open Access
    Review
    Beyond MHC binding: immunogenicity prediction tools to refine neoantigen selection in cancer patients
    In the last years, multiple efforts have been made to accurately predict neoantigens derived from somatic mutations in cancer patients, either to develop personalized therapeutic vaccines or to stud [...] Read more.
    Ibel Carri ... María Marcela Barrio
    Published: April 25, 2023 Explor Immunol. 2023;3:82–103
    DOI: https://doi.org/10.37349/ei.2023.00091
    This article belongs to the special issue Bioinformatics, Big Data, AI: Exploring Immunology
    View:279
    Download:22
    Times Cited: 0
    Open Access
    Review
    Inflammasomes driven inflammation in lung cancer revisited: a short review
    Lung cancer is the leading cause of cancer-related deaths worldwide. The main risk factor for lung cancer is exposure to chemicals present in cigarettes and atmospheric pollutants, which, among othe [...] Read more.
    Vitor Rodrigues da Costa ... Rodrigo Pinheiro Araldi
    Published: March 14, 2023 Explor Immunol. 2023;3:70–81
    DOI: https://doi.org/10.37349/ei.2023.00090
    This article belongs to the special issue DNA Sensing in Lung Inflammation
    View:340
    Download:43
    Times Cited: 0
    Open Access
    Review
    The role of interleukin-24 in atopic dermatitis
    Atopic dermatitis (AD) is characterized by skin barrier disruption, type 2 immune dysregulation, chronic pruritus, and abnormal colonization by Staphylococcus aureus (S. aureus). Tapinarof, an aryl  [...] Read more.
    Yen Hai Vu ... Gaku Tsuji
    Published: April 30, 2021 Explor Immunol. 2021;1:4–15
    DOI: https://doi.org/10.37349/ei.2021.00002
    This article belongs to the special issue Cross Talk Among Skin Cells and Immune Cells
    View:4174
    Download:171
    Times Cited: 0
    Open Access
    Review
    Viral vector-based vaccines against SARS-CoV-2
    Viral vectors have been frequently applied for vaccine development. It has also been the case for vaccines against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) to tackle the coronavi [...] Read more.
    Kenneth Lundstrom
    Published: October 31, 2021 Explor Immunol. 2021;1:295–308
    DOI: https://doi.org/10.37349/ei.2021.00020
    This article belongs to the special issue Vaccine-induced Immune Responses Against SARS-CoV-2 Infections
    View:2976
    Download:83
    Open Access
    Review
    Immunology of biodegradable nanoparticles: a brief overview on a wide growing field
    Immunity is continuously evolving by evolutionary mechanisms shaped by pathogenic stimuli of different kinds. Man-made nanomaterials (NMs) have been developed in the last decades and represent a nov [...] Read more.
    Anissa Pisani, Giuseppe Bardi
    Published: April 30, 2021 Explor Immunol. 2021;1:48–60
    DOI: https://doi.org/10.37349/ei.2021.00006
    View:2842
    Download:166
    Open Access
    Review
    Immune responses induced by different vaccine platforms against coronavirus disease-19
    There have been significant developments in the design of nanostructured scaffolds for eliciting robust immune responses named vaccine. The technique is to produce strong immune responses is to mani [...] Read more.
    Eknath D. Ahire, Sanjay J. Kshirsagar
    Published: October 31, 2021 Explor Immunol. 2021;1:243–257
    DOI: https://doi.org/10.37349/ei.2021.00016
    This article belongs to the special issue Vaccine-induced Immune Responses Against SARS-CoV-2 Infections
    View:2709
    Download:108
    Open Access
    Editorial
    Exploration of Immunology: challenging knowledge, developing curiosity and transforming passion into discovery
    Dominique J Charron, Reem Al-Daccak
    Published: April 30, 2021 Explor Immunol. 2021;1:1–3
    DOI: https://doi.org/10.37349/ei.2021.00001
    View:2556
    Download:62
    Times Cited: 0
    Open Access
    Review
    Interplay between mesenchymal stromal cells and immune system: clinical applications in immune-related diseases
    Mesenchymal stromal cells (MSCs) are a mesodermal stem cell population, with known self-renewal and multilineage differentiation properties. In the last century, MSCs have been widely used in regene [...] Read more.
    Panagiotis Mallis ... Catherine Stavropoulos Giokas
    Published: June 30, 2021 Explor Immunol. 2021;1:112–139
    DOI: https://doi.org/10.37349/ei.2021.00010
    View:2394
    Download:70
    Open Access
    Review
    The role of interleukin-24 in atopic dermatitis
    Atopic dermatitis (AD) is characterized by skin barrier disruption, type 2 immune dysregulation, chronic pruritus, and abnormal colonization by Staphylococcus aureus (S. aureus). Tapinarof, an aryl  [...] Read more.
    Yen Hai Vu ... Gaku Tsuji
    Published: April 30, 2021 Explor Immunol. 2021;1:4–15
    DOI: https://doi.org/10.37349/ei.2021.00002
    This article belongs to the special issue Cross Talk Among Skin Cells and Immune Cells
    View:4174
    Download:171
    Times Cited: 0
    Open Access
    Review
    Immunology of biodegradable nanoparticles: a brief overview on a wide growing field
    Immunity is continuously evolving by evolutionary mechanisms shaped by pathogenic stimuli of different kinds. Man-made nanomaterials (NMs) have been developed in the last decades and represent a nov [...] Read more.
    Anissa Pisani, Giuseppe Bardi
    Published: April 30, 2021 Explor Immunol. 2021;1:48–60
    DOI: https://doi.org/10.37349/ei.2021.00006
    View:2842
    Download:166
    Open Access
    Review
    Chemokines and nanomaterials: interaction for useful immune-applications
    Chemokines are homeostatic or inflammatory small proteins regulating immune cell migration and are structurally characterized by cysteine disulfide bridges. Around 50 human chemokines binding almost [...] Read more.
    Giuseppe Bardi
    Published: August 31, 2022 Explor Immunol. 2022;2:637–647
    DOI: https://doi.org/10.37349/ei.2022.00073
    This article belongs to the special issue Nanomaterials interaction with chemokines: perspectives for applied immunology
    View:655
    Download:122
    Times Cited: 0
    Open Access
    Review
    Immune responses induced by different vaccine platforms against coronavirus disease-19
    There have been significant developments in the design of nanostructured scaffolds for eliciting robust immune responses named vaccine. The technique is to produce strong immune responses is to mani [...] Read more.
    Eknath D. Ahire, Sanjay J. Kshirsagar
    Published: October 31, 2021 Explor Immunol. 2021;1:243–257
    DOI: https://doi.org/10.37349/ei.2021.00016
    This article belongs to the special issue Vaccine-induced Immune Responses Against SARS-CoV-2 Infections
    View:2709
    Download:108
    Open Access
    Review
    Skin and immune cells crosstalk via circadian regulations
    Both innate and adaptive immune cells exist in the skin, predominantly in the dermis layer. Recent studies have focused on how and which circadian rhythms contribute to maintain good health. Over re [...] Read more.
    Kanami Orihara
    Published: October 31, 2021 Explor Immunol. 2021;1:285–294
    DOI: https://doi.org/10.37349/ei.2021.00019
    This article belongs to the special issue Cross Talk Among Skin Cells and Immune Cells
    View:1479
    Download:107
    Open Access
    Review
    Macrophages and fibroblasts underpin skin immune responses
    There are various types of skin immune responses including inflammatory skin diseases and skin malignancy. Macrophages and fibroblasts are skin resident cells that had been overlooked in terms of im [...] Read more.
    Makoto Sugaya
    Published: August 31, 2021 Explor Immunol. 2021;1:226–242
    DOI: https://doi.org/10.37349/ei.2021.00015
    This article belongs to the special issue Cross Talk Among Skin Cells and Immune Cells
    View:1619
    Download:102
    Times Cited: 0
    Open Access
    Review
    Immunology of biodegradable nanoparticles: a brief overview on a wide growing field
    Immunity is continuously evolving by evolutionary mechanisms shaped by pathogenic stimuli of different kinds. Man-made nanomaterials (NMs) have been developed in the last decades and represent a nov [...] Read more.
    Anissa Pisani, Giuseppe Bardi
    Published: April 30, 2021 Explor Immunol. 2021;1:48–60
    DOI: https://doi.org/10.37349/ei.2021.00006
    View:2842
    Download:166
    Open Access
    Review
    The protective immunity induced by SARS-CoV-2 infection and vaccination: a critical appraisal
    Understanding the interactions of severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) with humans is deeply grounded in immunology, from the diagnosis to pathogenesis, from the clinical pre [...] Read more.
    Eduardo Tosta
    Published: August 31, 2021 Explor Immunol. 2021;1:199–225
    DOI: https://doi.org/10.37349/ei.2021.00014
    This article belongs to the special issue Vaccine-induced Immune Responses Against SARS-CoV-2 Infections
    View:1696
    Download:52
    Open Access
    Review
    Crosstalk between keratinocytes and immune cells in inflammatory skin diseases
    Cutaneous homeostasis is maintained by dynamic cellular communications between different cell types in the skin through interactions with various mediators, including cytokines, chemokines and antim [...] Read more.
    Xinhui Ni, Yuping Lai
    Published: December 31, 2021 Explor Immunol. 2021;1:418–431
    DOI: https://doi.org/10.37349/ei.2021.00028
    This article belongs to the special issue Cross Talk Among Skin Cells and Immune Cells
    View:1175
    Download:101
    Open Access
    Review
    High avidity of vaccine-induced immunoglobulin G against SARS-CoV-2: potential relevance for protective humoral immunity
    Avidity of immunoglobulin G (IgG) is defined as its binding strength to its target antigen. As a consequence of affinity maturation of the IgG response, avidity is maturing as well. Therefore, acute [...] Read more.
    Georg Bauer
    Published: March 16, 2022 Explor Immunol. 2022;2:133–156
    DOI: https://doi.org/10.37349/ei.2022.00040
    This article belongs to the special issue Vaccine-induced Immune Responses Against SARS-CoV-2 Infections
    View:1080
    Download:49
    Open Access
    Review
    Interplay between mesenchymal stromal cells and immune system: clinical applications in immune-related diseases
    Mesenchymal stromal cells (MSCs) are a mesodermal stem cell population, with known self-renewal and multilineage differentiation properties. In the last century, MSCs have been widely used in regene [...] Read more.
    Panagiotis Mallis ... Catherine Stavropoulos Giokas
    Published: June 30, 2021 Explor Immunol. 2021;1:112–139
    DOI: https://doi.org/10.37349/ei.2021.00010
    View:2394
    Download:70
    Open Access
    Review
    Viral vector-based vaccines against SARS-CoV-2
    Viral vectors have been frequently applied for vaccine development. It has also been the case for vaccines against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) to tackle the coronavi [...] Read more.
    Kenneth Lundstrom
    Published: October 31, 2021 Explor Immunol. 2021;1:295–308
    DOI: https://doi.org/10.37349/ei.2021.00020
    This article belongs to the special issue Vaccine-induced Immune Responses Against SARS-CoV-2 Infections
    View:2976
    Download:83
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