• Exploration of Immunology

    eISSN: 2768-6655
    EiC: Dominique J. Charron, MD, PhD, Hospital Saint Louis
    Adjunct-EiC: Reem Al-Daccak, PhD, Hospital Saint Louis
    Frequency: Bimonthly
    APC: No Article Processing Charge
    Publishing Model: Open Access
    Peer Review Model: Single Blind
    Permanent Archive: Portico
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    Articles
    Open Access
    Review
    Immunopathogenesis of severe acute respiratory syndrome coronavirus-2: evolving knowledge and its current status
    As the severe acute respiratory syndrome coronavirus (SARS-CoV)-2 is a new virus, the current knowledge on the immunopathogenesis of this newly emerged SARS-CoV-2 is beginning to unravel with intens...
    Nitin Saksena ... Monica Miranda-Saksena
    Published: June 30, 2021 Explor Immunol. 2021;1:61-79
    DOI: https://doi.org/10.37349/ei.2021.00007
    View:279
    Download:28
    Times Cited: 0
    Open Access
    Review
    L-arginine as a novel target for clinical intervention in inflammatory bowel disease
    Arginase-1 (Arg1) and the inducible nitric oxide synthase 2 (NOS2) compete for the common substrate L-arginine, semi-essential amino acid, and central intestinal metabolite. Both enzymes exhibit var...
    Björn Nüse, Jochen Mattner
    Published: June 30, 2021 Explor Immunol. 2021;1:80-89
    DOI: https://doi.org/10.37349/ei.2021.00008
    View:205
    Download:28
    Times Cited: 0
    Open Access
    Review
    Vitamin D and immunomodulation in the skin: a useful affirmative nexus
    Skin is the largest organ of the body having multifunctional activities. It has a dynamic cellular network with unique immunologic properties to maintain defensive actions, photoprotection, immune r...
    Saptadip Samanta
    Published: June 30, 2021 Explor Immunol. 2021;1:90-111
    DOI: https://doi.org/10.37349/ei.2021.00009
    This article belongs to the special issue Cross Talk Among Skin Cells and Immune Cells
    View:174
    Download:10
    Times Cited: 0
    Open Access
    Review
    Interplay between mesenchymal stromal cells and immune system: clinical applications in immune-related diseases
    Mesenchymal stromal cells (MSCs) are a mesodermal stem cell population, with known self-renewal and multilineage differentiation properties. In the last century, MSCs have been widely used in regene...
    Panagiotis Mallis ... Catherine Stavropoulos Giokas
    Published: June 30, 2021 Explor Immunol. 2021;1:112-139
    DOI: https://doi.org/10.37349/ei.2021.00010
    View:189
    Download:13
    Times Cited: 0
    Open Access
    Review
    Immunology of biodegradable nanoparticles: a brief overview on a wide growing field
    Immunity is continuously evolving by evolutionary mechanisms shaped by pathogenic stimuli of different kinds. Man-made nanomaterials (NMs) have been developed in the last decades and represent a nov...
    Anissa Pisani, Giuseppe Bardi
    Published: April 30, 2021 Explor Immunol. 2021;1:48-60
    DOI: https://doi.org/10.37349/ei.2021.00006
    View:574
    Download:35
    Times Cited: 0
    Open Access
    Review
    Interleukin-22 and keratinocytes; pathogenic implications in skin inflammation
    Interleukin (IL)-22 is produced from immune cells such as T helper (Th)22 cells, Th17/22 cells, and group 3 innate lymphoid cells. IL-22 signals via the IL-22 receptor 1 (IL-22R1) and the IL-10 rece...
    Masutaka Furue, Mihoko Furue
    Published: April 30, 2021 Explor Immunol. 2021;1:37-47
    DOI: https://doi.org/10.37349/ei.2021.00005
    This article belongs to the special issue Cross Talk Among Skin Cells and Immune Cells
    View:468
    Download:28
    Times Cited: 0
    Open Access
    Editorial
    Exploration of Immunology: challenging knowledge, developing curiosity and transforming passion into discovery
    Dominique J Charron, Reem Al-Daccak
    Published: April 30, 2021 Explor Immunol. 2021;1:1-3
    DOI: https://doi.org/10.37349/ei.2021.00001
    View:1289
    Download:52
    Times Cited: 0
    Open Access
    Review
    The role of interleukin-24 in atopic dermatitis
    Atopic dermatitis (AD) is characterized by skin barrier disruption, type 2 immune dysregulation, chronic pruritus, and abnormal colonization by Staphylococcus aureus (S. aureus). Tapinarof, an aryl ...
    Yen Hai Vu ... Gaku Tsuji
    Published: April 30, 2021 Explor Immunol. 2021;1:4-15
    DOI: https://doi.org/10.37349/ei.2021.00002
    This article belongs to the special issue Cross Talk Among Skin Cells and Immune Cells
    View:1222
    Download:86
    Times Cited: 0
    Open Access
    Original Article
    In silico investigation of binding affinities between human leukocyte antigen class I molecules and SARS-CoV-2 virus spike and ORF1ab proteins
    Aim: The novel coronavirus severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) causes coronavirus disease 2019, a global pandemic. There is hence an urgent need for effective approaches to...
    Spyros A. Charonis ... Apostolos P. Georgopoulos
    Published: April 30, 2021 Explor Immunol. 2021;1:16-26
    DOI: https://doi.org/10.37349/ei.2021.00003
    View:920
    Download:31
    Times Cited: 0
    Open Access
    Review
    Immunology of biodegradable nanoparticles: a brief overview on a wide growing field
    Immunity is continuously evolving by evolutionary mechanisms shaped by pathogenic stimuli of different kinds. Man-made nanomaterials (NMs) have been developed in the last decades and represent a nov...
    Anissa Pisani, Giuseppe Bardi
    Published: April 30, 2021 Explor Immunol. 2021;1:48-60
    DOI: https://doi.org/10.37349/ei.2021.00006
    View:574
    Download:35
    Times Cited: 0
    Open Access
    Review
    Interleukin-22 and keratinocytes; pathogenic implications in skin inflammation
    Interleukin (IL)-22 is produced from immune cells such as T helper (Th)22 cells, Th17/22 cells, and group 3 innate lymphoid cells. IL-22 signals via the IL-22 receptor 1 (IL-22R1) and the IL-10 rece...
    Masutaka Furue, Mihoko Furue
    Published: April 30, 2021 Explor Immunol. 2021;1:37-47
    DOI: https://doi.org/10.37349/ei.2021.00005
    This article belongs to the special issue Cross Talk Among Skin Cells and Immune Cells
    View:468
    Download:28
    Times Cited: 0
    Open Access
    Original Article
    Correlation of N-glycan dynamics and interaction network with allosteric antigen binding and Fc receptor recognition
    Aim: Fragment crystallizable (Fc) glycans modulate Fc conformations and functions, and glycan may also regulate antigen recognition. In the antibody drug development, glycosylation patterns affect a...
    Buyong Ma
    Published: April 30, 2021 Explor Immunol. 2021;1:27-36
    DOI: https://doi.org/10.37349/ei.2021.00004
    View:438
    Download:11
    Times Cited: 0
    Open Access
    Review
    The role of interleukin-24 in atopic dermatitis
    Atopic dermatitis (AD) is characterized by skin barrier disruption, type 2 immune dysregulation, chronic pruritus, and abnormal colonization by Staphylococcus aureus (S. aureus). Tapinarof, an aryl ...
    Yen Hai Vu ... Gaku Tsuji
    Published: April 30, 2021 Explor Immunol. 2021;1:4-15
    DOI: https://doi.org/10.37349/ei.2021.00002
    This article belongs to the special issue Cross Talk Among Skin Cells and Immune Cells
    View:1222
    Download:86
    Times Cited: 0
    Open Access
    Editorial
    Exploration of Immunology: challenging knowledge, developing curiosity and transforming passion into discovery
    Dominique J Charron, Reem Al-Daccak
    Published: April 30, 2021 Explor Immunol. 2021;1:1-3
    DOI: https://doi.org/10.37349/ei.2021.00001
    View:1289
    Download:52
    Times Cited: 0
    Open Access
    Review
    Immunology of biodegradable nanoparticles: a brief overview on a wide growing field
    Immunity is continuously evolving by evolutionary mechanisms shaped by pathogenic stimuli of different kinds. Man-made nanomaterials (NMs) have been developed in the last decades and represent a nov...
    Anissa Pisani, Giuseppe Bardi
    Published: April 30, 2021 Explor Immunol. 2021;1:48-60
    DOI: https://doi.org/10.37349/ei.2021.00006
    View:574
    Download:35
    Times Cited: 0
    Open Access
    Original Article
    In silico investigation of binding affinities between human leukocyte antigen class I molecules and SARS-CoV-2 virus spike and ORF1ab proteins
    Aim: The novel coronavirus severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) causes coronavirus disease 2019, a global pandemic. There is hence an urgent need for effective approaches to...
    Spyros A. Charonis ... Apostolos P. Georgopoulos
    Published: April 30, 2021 Explor Immunol. 2021;1:16-26
    DOI: https://doi.org/10.37349/ei.2021.00003
    View:920
    Download:31
    Times Cited: 0
    Open Access
    Review
    Interleukin-22 and keratinocytes; pathogenic implications in skin inflammation
    Interleukin (IL)-22 is produced from immune cells such as T helper (Th)22 cells, Th17/22 cells, and group 3 innate lymphoid cells. IL-22 signals via the IL-22 receptor 1 (IL-22R1) and the IL-10 rece...
    Masutaka Furue, Mihoko Furue
    Published: April 30, 2021 Explor Immunol. 2021;1:37-47
    DOI: https://doi.org/10.37349/ei.2021.00005
    This article belongs to the special issue Cross Talk Among Skin Cells and Immune Cells
    View:468
    Download:28
    Times Cited: 0
    Open Access
    Review
    Immunopathogenesis of severe acute respiratory syndrome coronavirus-2: evolving knowledge and its current status
    As the severe acute respiratory syndrome coronavirus (SARS-CoV)-2 is a new virus, the current knowledge on the immunopathogenesis of this newly emerged SARS-CoV-2 is beginning to unravel with intens...
    Nitin Saksena ... Monica Miranda-Saksena
    Published: June 30, 2021 Explor Immunol. 2021;1:61-79
    DOI: https://doi.org/10.37349/ei.2021.00007
    View:279
    Download:28
    Times Cited: 0
    Open Access
    Editorial
    Exploration of Immunology: challenging knowledge, developing curiosity and transforming passion into discovery
    Dominique J Charron, Reem Al-Daccak
    Published: April 30, 2021 Explor Immunol. 2021;1:1-3
    DOI: https://doi.org/10.37349/ei.2021.00001
    View:1289
    Download:52
    Times Cited: 0
    Open Access
    Review
    The role of interleukin-24 in atopic dermatitis
    Atopic dermatitis (AD) is characterized by skin barrier disruption, type 2 immune dysregulation, chronic pruritus, and abnormal colonization by Staphylococcus aureus (S. aureus). Tapinarof, an aryl ...
    Yen Hai Vu ... Gaku Tsuji
    Published: April 30, 2021 Explor Immunol. 2021;1:4-15
    DOI: https://doi.org/10.37349/ei.2021.00002
    This article belongs to the special issue Cross Talk Among Skin Cells and Immune Cells
    View:1222
    Download:86
    Times Cited: 0
    Open Access
    Original Article
    In silico investigation of binding affinities between human leukocyte antigen class I molecules and SARS-CoV-2 virus spike and ORF1ab proteins
    Aim: The novel coronavirus severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) causes coronavirus disease 2019, a global pandemic. There is hence an urgent need for effective approaches to...
    Spyros A. Charonis ... Apostolos P. Georgopoulos
    Published: April 30, 2021 Explor Immunol. 2021;1:16-26
    DOI: https://doi.org/10.37349/ei.2021.00003
    View:920
    Download:31
    Times Cited: 0
    Open Access
    Original Article
    Correlation of N-glycan dynamics and interaction network with allosteric antigen binding and Fc receptor recognition
    Aim: Fragment crystallizable (Fc) glycans modulate Fc conformations and functions, and glycan may also regulate antigen recognition. In the antibody drug development, glycosylation patterns affect a...
    Buyong Ma
    Published: April 30, 2021 Explor Immunol. 2021;1:27-36
    DOI: https://doi.org/10.37349/ei.2021.00004
    View:438
    Download:11
    Times Cited: 0
    Open Access
    Review
    Interleukin-22 and keratinocytes; pathogenic implications in skin inflammation
    Interleukin (IL)-22 is produced from immune cells such as T helper (Th)22 cells, Th17/22 cells, and group 3 innate lymphoid cells. IL-22 signals via the IL-22 receptor 1 (IL-22R1) and the IL-10 rece...
    Masutaka Furue, Mihoko Furue
    Published: April 30, 2021 Explor Immunol. 2021;1:37-47
    DOI: https://doi.org/10.37349/ei.2021.00005
    This article belongs to the special issue Cross Talk Among Skin Cells and Immune Cells
    View:468
    Download:28
    Times Cited: 0
    Open Access
    Review
    Immunology of biodegradable nanoparticles: a brief overview on a wide growing field
    Immunity is continuously evolving by evolutionary mechanisms shaped by pathogenic stimuli of different kinds. Man-made nanomaterials (NMs) have been developed in the last decades and represent a nov...
    Anissa Pisani, Giuseppe Bardi
    Published: April 30, 2021 Explor Immunol. 2021;1:48-60
    DOI: https://doi.org/10.37349/ei.2021.00006
    View:574
    Download:35
    Times Cited: 0
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