• Exploration of Immunology

    eISSN: 2768-6655
    EiC: Dominique J. Charron, MD, PhD, Hospital Saint Louis
    Adjunct-EiC: Reem Al-Daccak, PhD, Hospital Saint Louis
    Frequency: Bimonthly
    APC: No Article Processing Charge
    Publishing Model: Open Access
    Peer Review Model: Single Blind
    Permanent Archive: Portico
    Indexing & Archiving: Dimensions, DOAJ, J-Gate, Portico, ResearchGate, ICMJE, etc
    Follow the journal:
    Follow the journal:
    Articles
    Open Access
    Review
    Viral vector-based vaccines against SARS-CoV-2
    Viral vectors have been frequently applied for vaccine development. It has also been the case for vaccines against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) to tackle the coronavi...
    Kenneth Lundstrom
    Published: October 31, 2021 Explor Immunol. 2021;1:295-308
    DOI: https://doi.org/10.37349/ei.2021.00020
    This article belongs to the special issue Vaccine-induced Immune Responses Against SARS-CoV-2 Infections
    View:290
    Download:40
    Times Cited: 0
    Open Access
    Review
    Skin and immune cells crosstalk via circadian regulations
    Both innate and adaptive immune cells exist in the skin, predominantly in the dermis layer. Recent studies have focused on how and which circadian rhythms contribute to maintain good health. Over re...
    Kanami Orihara
    Published: October 31, 2021 Explor Immunol. 2021;1:285-294
    DOI: https://doi.org/10.37349/ei.2021.00019
    This article belongs to the special issue Cross Talk Among Skin Cells and Immune Cells
    View:178
    Download:40
    Times Cited: 0
    Open Access
    Original Article
    The two faces of mast cells in vitiligo pathogenesis
    Aim: Previously, we reported increased number of T helper 17 (Th17) cells in vitiligo. However, in our recent study, tryptase and interleukin (IL)17 double positive cells which identified by polycl...
    Ichiro Katayama ... Mari Wataya-Kaneda
    Published: October 31, 2021 Explor Immunol. 2021;1:269-284
    DOI: https://doi.org/10.37349/ei.2021.00018
    This article belongs to the special issue Cross Talk Among Skin Cells and Immune Cells
    View:243
    Download:40
    Times Cited: 0
    Open Access
    Original Article
    Serum profiles of tryptophan-kynurenine pathway metabolites in psoriasis
    Aim: Chronic inflammation is closely associated with tryptophan (TRP)-kynurenine (KYN) metabolic pathway. However, TRP-KYN pathway has not been fully elucidated in psoriasis, a systemic inflammator...
    Mariko Seishima ... Kuniaki Saito
    Published: October 31, 2021 Explor Immunol. 2021;1:258-268
    DOI: https://doi.org/10.37349/ei.2021.00017
    This article belongs to the special issue Cross Talk Among Skin Cells and Immune Cells
    View:201
    Download:22
    Times Cited: 0
    Open Access
    Review
    Immune responses induced by different vaccine platforms against coronavirus disease-19
    There have been significant developments in the design of nanostructured scaffolds for eliciting robust immune responses named vaccine. The technique is to produce strong immune responses is to mani...
    Eknath D. Ahire, Sanjay J. Kshirsagar
    Published: October 31, 2021 Explor Immunol. 2021;1:243-257
    DOI: https://doi.org/10.37349/ei.2021.00016
    This article belongs to the special issue Vaccine-induced Immune Responses Against SARS-CoV-2 Infections
    View:392
    Download:26
    Times Cited: 0
    Open Access
    Review
    Severe acute respiratory syndrome coronavirus 2 targeted antibodies cocktail and B cell receptor interplay: interventions to trigger vaccine development
    Coronavirus disease-2019 (COVID-19) caused by severe acute respiratory syndrome coronavirus (SARS-CoV)-2 spread globally and creates an alarming situation. Following the SARS-CoV-2 paradigm, therape...
    Kabeer Haneef ... Zainab Fatima
    Published: August 31, 2021 Explor Immunol. 2021;1:140-154
    DOI: https://doi.org/10.37349/ei.2021.00011
    This article belongs to the special issue Vaccine-induced Immune Responses Against SARS-CoV-2 Infections
    View:557
    Download:45
    Times Cited: 0
    Open Access
    Review
    The role of interleukin-24 in atopic dermatitis
    Atopic dermatitis (AD) is characterized by skin barrier disruption, type 2 immune dysregulation, chronic pruritus, and abnormal colonization by Staphylococcus aureus (S. aureus). Tapinarof, an aryl ...
    Yen Hai Vu ... Gaku Tsuji
    Published: April 30, 2021 Explor Immunol. 2021;1:4-15
    DOI: https://doi.org/10.37349/ei.2021.00002
    This article belongs to the special issue Cross Talk Among Skin Cells and Immune Cells
    View:1918
    Download:102
    Times Cited: 0
    Open Access
    Editorial
    Exploration of Immunology: challenging knowledge, developing curiosity and transforming passion into discovery
    Dominique J Charron, Reem Al-Daccak
    Published: April 30, 2021 Explor Immunol. 2021;1:1-3
    DOI: https://doi.org/10.37349/ei.2021.00001
    View:1655
    Download:54
    Times Cited: 0
    Open Access
    Original Article
    In silico investigation of binding affinities between human leukocyte antigen class I molecules and SARS-CoV-2 virus spike and ORF1ab proteins
    Aim: The novel coronavirus severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) causes coronavirus disease 2019, a global pandemic. There is hence an urgent need for effective approaches to...
    Spyros A. Charonis ... Apostolos P. Georgopoulos
    Published: April 30, 2021 Explor Immunol. 2021;1:16-26
    DOI: https://doi.org/10.37349/ei.2021.00003
    View:1107
    Download:38
    Times Cited: 0
    Open Access
    Review
    Immunology of biodegradable nanoparticles: a brief overview on a wide growing field
    Immunity is continuously evolving by evolutionary mechanisms shaped by pathogenic stimuli of different kinds. Man-made nanomaterials (NMs) have been developed in the last decades and represent a nov...
    Anissa Pisani, Giuseppe Bardi
    Published: April 30, 2021 Explor Immunol. 2021;1:48-60
    DOI: https://doi.org/10.37349/ei.2021.00006
    View:997
    Download:56
    Times Cited: 0
    Open Access
    Review
    Interleukin-22 and keratinocytes; pathogenic implications in skin inflammation
    Interleukin (IL)-22 is produced from immune cells such as T helper (Th)22 cells, Th17/22 cells, and group 3 innate lymphoid cells. IL-22 signals via the IL-22 receptor 1 (IL-22R1) and the IL-10 rece...
    Masutaka Furue, Mihoko Furue
    Published: April 30, 2021 Explor Immunol. 2021;1:37-47
    DOI: https://doi.org/10.37349/ei.2021.00005
    This article belongs to the special issue Cross Talk Among Skin Cells and Immune Cells
    View:991
    Download:41
    Times Cited: 0
    Open Access
    Review
    Vitamin D and immunomodulation in the skin: a useful affirmative nexus
    Skin is the largest organ of the body having multifunctional activities. It has a dynamic cellular network with unique immunologic properties to maintain defensive actions, photoprotection, immune r...
    Saptadip Samanta
    Published: June 30, 2021 Explor Immunol. 2021;1:90-111
    DOI: https://doi.org/10.37349/ei.2021.00009
    This article belongs to the special issue Cross Talk Among Skin Cells and Immune Cells
    View:810
    Download:35
    Times Cited: 0
    Open Access
    Review
    The role of interleukin-24 in atopic dermatitis
    Atopic dermatitis (AD) is characterized by skin barrier disruption, type 2 immune dysregulation, chronic pruritus, and abnormal colonization by Staphylococcus aureus (S. aureus). Tapinarof, an aryl ...
    Yen Hai Vu ... Gaku Tsuji
    Published: April 30, 2021 Explor Immunol. 2021;1:4-15
    DOI: https://doi.org/10.37349/ei.2021.00002
    This article belongs to the special issue Cross Talk Among Skin Cells and Immune Cells
    View:1918
    Download:102
    Times Cited: 0
    Open Access
    Review
    Immunology of biodegradable nanoparticles: a brief overview on a wide growing field
    Immunity is continuously evolving by evolutionary mechanisms shaped by pathogenic stimuli of different kinds. Man-made nanomaterials (NMs) have been developed in the last decades and represent a nov...
    Anissa Pisani, Giuseppe Bardi
    Published: April 30, 2021 Explor Immunol. 2021;1:48-60
    DOI: https://doi.org/10.37349/ei.2021.00006
    View:997
    Download:56
    Times Cited: 0
    Open Access
    Editorial
    Exploration of Immunology: challenging knowledge, developing curiosity and transforming passion into discovery
    Dominique J Charron, Reem Al-Daccak
    Published: April 30, 2021 Explor Immunol. 2021;1:1-3
    DOI: https://doi.org/10.37349/ei.2021.00001
    View:1655
    Download:54
    Times Cited: 0
    Open Access
    Review
    Immunopathogenesis of severe acute respiratory syndrome coronavirus-2: evolving knowledge and its current status
    As the severe acute respiratory syndrome coronavirus (SARS-CoV)-2 is a new virus, the current knowledge on the immunopathogenesis of this newly emerged SARS-CoV-2 is beginning to unravel with intens...
    Nitin Saksena ... Monica Miranda-Saksena
    Published: June 30, 2021 Explor Immunol. 2021;1:61-79
    DOI: https://doi.org/10.37349/ei.2021.00007
    View:681
    Download:54
    Times Cited: 0
    Open Access
    Review
    L-arginine as a novel target for clinical intervention in inflammatory bowel disease
    Arginase-1 (Arg1) and the inducible nitric oxide synthase 2 (NOS2) compete for the common substrate L-arginine, semi-essential amino acid, and central intestinal metabolite. Both enzymes exhibit var...
    Björn Nüse, Jochen Mattner
    Published: June 30, 2021 Explor Immunol. 2021;1:80-89
    DOI: https://doi.org/10.37349/ei.2021.00008
    View:610
    Download:49
    Times Cited: 0
    Open Access
    Review
    Severe acute respiratory syndrome coronavirus 2 targeted antibodies cocktail and B cell receptor interplay: interventions to trigger vaccine development
    Coronavirus disease-2019 (COVID-19) caused by severe acute respiratory syndrome coronavirus (SARS-CoV)-2 spread globally and creates an alarming situation. Following the SARS-CoV-2 paradigm, therape...
    Kabeer Haneef ... Zainab Fatima
    Published: August 31, 2021 Explor Immunol. 2021;1:140-154
    DOI: https://doi.org/10.37349/ei.2021.00011
    This article belongs to the special issue Vaccine-induced Immune Responses Against SARS-CoV-2 Infections
    View:557
    Download:45
    Times Cited: 0
    Open Access
    Review
    Interplay between mesenchymal stromal cells and immune system: clinical applications in immune-related diseases
    Mesenchymal stromal cells (MSCs) are a mesodermal stem cell population, with known self-renewal and multilineage differentiation properties. In the last century, MSCs have been widely used in regene...
    Panagiotis Mallis ... Catherine Stavropoulos Giokas
    Published: June 30, 2021 Explor Immunol. 2021;1:112-139
    DOI: https://doi.org/10.37349/ei.2021.00010
    View:585
    Download:26
    Open Access
    Editorial
    Exploration of Immunology: challenging knowledge, developing curiosity and transforming passion into discovery
    Dominique J Charron, Reem Al-Daccak
    Published: April 30, 2021 Explor Immunol. 2021;1:1-3
    DOI: https://doi.org/10.37349/ei.2021.00001
    View:1655
    Download:54
    Times Cited: 0
    Open Access
    Review
    The role of interleukin-24 in atopic dermatitis
    Atopic dermatitis (AD) is characterized by skin barrier disruption, type 2 immune dysregulation, chronic pruritus, and abnormal colonization by Staphylococcus aureus (S. aureus). Tapinarof, an aryl ...
    Yen Hai Vu ... Gaku Tsuji
    Published: April 30, 2021 Explor Immunol. 2021;1:4-15
    DOI: https://doi.org/10.37349/ei.2021.00002
    This article belongs to the special issue Cross Talk Among Skin Cells and Immune Cells
    View:1918
    Download:102
    Times Cited: 0
    Open Access
    Original Article
    In silico investigation of binding affinities between human leukocyte antigen class I molecules and SARS-CoV-2 virus spike and ORF1ab proteins
    Aim: The novel coronavirus severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) causes coronavirus disease 2019, a global pandemic. There is hence an urgent need for effective approaches to...
    Spyros A. Charonis ... Apostolos P. Georgopoulos
    Published: April 30, 2021 Explor Immunol. 2021;1:16-26
    DOI: https://doi.org/10.37349/ei.2021.00003
    View:1107
    Download:38
    Times Cited: 0
    Open Access
    Original Article
    Correlation of N-glycan dynamics and interaction network with allosteric antigen binding and Fc receptor recognition
    Aim: Fragment crystallizable (Fc) glycans modulate Fc conformations and functions, and glycan may also regulate antigen recognition. In the antibody drug development, glycosylation patterns affect a...
    Buyong Ma
    Published: April 30, 2021 Explor Immunol. 2021;1:27-36
    DOI: https://doi.org/10.37349/ei.2021.00004
    View:611
    Download:14
    Times Cited: 0
    Open Access
    Review
    Interleukin-22 and keratinocytes; pathogenic implications in skin inflammation
    Interleukin (IL)-22 is produced from immune cells such as T helper (Th)22 cells, Th17/22 cells, and group 3 innate lymphoid cells. IL-22 signals via the IL-22 receptor 1 (IL-22R1) and the IL-10 rece...
    Masutaka Furue, Mihoko Furue
    Published: April 30, 2021 Explor Immunol. 2021;1:37-47
    DOI: https://doi.org/10.37349/ei.2021.00005
    This article belongs to the special issue Cross Talk Among Skin Cells and Immune Cells
    View:991
    Download:41
    Times Cited: 0
    Special Issues