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    The Nutritional Influence on Immune Functionality

    Submission Deadline: August 31, 2025

    Guest Editor

    Dr. Lucia Malaguarnera E-Mail

    Università degli Studi di Catania, Catania, Italy

    Research Keywords: Rheumatism and Immunity


    About the Special Issue

    In recent decades, much evidence has shown that a balanced diet rich in a variety of macro- and micronutrients helps to maintain a healthy immune system. In fact, sufficient amounts of minerals such as zinc and magnesium, micronutrients, herbs, and vitamin-rich foods can help the immune system function not only to prevent infections but also to respond more effectively to many pathological conditions such as hypersensitivity and autoimmune diseases. Nutritional status is closely linked to metabolic health status. Metabolic imbalances can induce alterations in immune function due to defective antioxidant mechanisms and microbiota disturbances.

    This issue aims to provide a comprehensive view of the scientific literature on a well-balanced diet in supporting optimal immune function by highlighting the importance of nutrients known for their potential to improve the functionality of various components of the immune system. Preclinical, clinical, meta-analysis studies, and analytical reviews will help to deepen the understanding of the molecular mechanisms used by minerals, vitamins, micronutrients, polyphenols, etc., through which nutrition can affect the immune response and its role in preventing numerous immunopathologies.

    Keywords: Nutritional influence, immune functionality, immune system

    Call for Papers

    Published Articles

    Open Access
    Original Article
    Impact of sucrose consumption on inflammatory and immunological parameters in newborn offspring of females mice with gestational diabetes mellitus
    Aim: This study aims to analyze the impact of sucrose consumption on inflammatory and immunological parameters of newborn offspring of females with gestational diabetes mellitus (GDM). Metho [...] Read more.
    Beatriz Elina Martínez-Carrillo ... Ana Laura Guadarrama-López
    Published: May 20, 2025 Explor Immunol. 2025;5:1003195
    DOI: https://doi.org/10.37349/ei.2025.1003195
    View:33
    Download:5
    Times Cited: 0
    Open Access
    Review
    Diets for inflammatory bowel disease: impact on microbiome and immunomodulatory microbial metabolites
    Diet plays a complex role in the management of inflammatory bowel disease (IBD), significantly influencing the microbiome and metabolome. Three key metabolites implicated in IBD are short chain fatt [...] Read more.
    Hebe Mendez, Ger Rijkers
    Published: April 08, 2025 Explor Immunol. 2025;5:1003191
    DOI: https://doi.org/10.37349/ei.2025.1003191
    View:531
    Download:17
    Times Cited: 0
    Open Access
    Original Article
    Flavonoids, nobiletin, heptamethoxyflavone, and genistein enhance antigen-presenting cell function in vitro
    Aim: Antigen (Ag) presentation by Ag-presenting cells (APCs) is the first step in the generation of adaptive humoral and cellular immune responses. However, there have been few studies on the eff [...] Read more.
    Yuko Tanaka ... Tohru Sakai
    Published: May 29, 2024 Explor Immunol. 2024;4:333–340
    DOI: https://doi.org/10.37349/ei.2024.00144
    View:1273
    Download:27