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  • Exploration of Neuroscience

    eISSN: 2834-5347
    EiC: Dirk M. Hermann, Germany
    Frequency: Continuous Publication
    APC: No Article Processing Charge before September 30, 2027
    Publishing Model: Open Access
    Peer Review Model: Single Blind
    Permanent Archive: Portico
    Indexing & Archiving: Google Scholar, DOAJ, Dimensions, Portico, etc.
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    Articles
    Open Access
    Case Report
    Isolated lymphoma of the choroid plexus: a case report
    The choroid plexus, pivotal for cerebrospinal fluid (CSF) regulation and blood-CSF barrier function, becomes a focal point for primary central nervous system lymphoma (PCNSL). This article delves in [...] Read more.
    Ali Msheik ... Zeinab Al Mokdad
    Published: May 20, 2025 Explor Neurosci. 2025;4:100689
    DOI: https://doi.org/10.37349/en.2025.100689
    View:12
    Download:3
    Times Cited: 0
    Open Access
    Review
    Association between CD36 and ischemic stroke: consequential or coincidental?
    CD36 is a transmembrane protein that plays a role in various biological processes, including oxidized low-density lipoprotein and fatty acid uptake as well as regulatory control for inflammation sig [...] Read more.
    Ana-Maria Dobri-Nicoară ... Cristiana Tanase
    Published: May 11, 2025 Explor Neurosci. 2025;4:100688
    DOI: https://doi.org/10.37349/en.2025.100688
    This article belongs to the special issue Cerebral Ischemia, Genetics, Comorbidities, Risk Factors and New Therapeutic Options for Neurorestoration
    View:127
    Download:6
    Times Cited: 0
    Open Access
    Original Article
    Intracerebral hemorrhage (ICH) in easternmost Finland 2021–2023
    Aim: To report the incidence, characteristics, and prognosis of spontaneous intracerebral hemorrhage (ICH) in North Karelia Central Hospital Primary Stroke Center (PSC). Methods: All patients admitted with ICH to North Karelia Cen [...] Read more.
    Jussi O.T. Sipilä ... Anne-Mari Kantanen
    Published: May 08, 2025 Explor Neurosci. 2025;4:100687
    DOI: https://doi.org/10.37349/en.2025.100687
    View:180
    Download:6
    Times Cited: 0
    Open Access
    Review
    Neuropathic pain: proposal of a mechanism-based treatment
    Neuropathic pain, defined by the International Association for the Study of Pain as “pain caused by a lesion or disease of the somatosensory system”, has an estimated prevalence of 7–9.2% in t [...] Read more.
    Laura Demartini, Cesare Bonezzi
    Published: April 27, 2025 Explor Neurosci. 2025;4:100686
    DOI: https://doi.org/10.37349/en.2025.100686
    This article belongs to the special issue Neuropathic Pain
    View:310
    Download:12
    Times Cited: 0
    Open Access
    Original Article
    Application of TELC model to better elucidate neural stimulation by touch
    Aim: This study is to better understand how the transient ion transport activity of touch receptors could change the graded potential to stimulate an action potential firing. Methods: The l [...] Read more.
    James Weifu Lee
    Published: April 26, 2025 Explor Neurosci. 2025;4:100685
    DOI: https://doi.org/10.37349/en.2025.100685
    View:214
    Download:8
    Times Cited: 0
    Open Access
    Original Article
    Correlation between self-perceived cognitive problems and objective cognitive impairment in non-CNS cancer patients in a resource-constrained health setting in South Africa
    Aim: Cognitive complaints are frequent among cancer patients. These issues can significantly affect the patient’s quality of life and are linked to a higher risk of developing dementia. However [...] Read more.
    Antonio G. Lentoor, Tiro B. Motsamai
    Published: April 16, 2025 Explor Neurosci. 2025;4:100684
    DOI: https://doi.org/10.37349/en.2025.100684
    View:308
    Download:5
    Times Cited: 0
    Open Access
    Review
    Current therapeutics for Alzheimer’s disease and clinical trials
    Alzheimer’s disease (AD) is a major type of dementia and neurodegenerative disease, characterized by memory loss and cognitive decline. Over decades, significant efforts have been dedicated to fin [...] Read more.
    Danqing Xiao, Chen Zhang
    Published: June 27, 2024 Explor Neurosci. 2024;3:255–271
    DOI: https://doi.org/10.37349/en.2024.00048
    This article belongs to the special issue Alzheimer’s Disease
    View:14065
    Download:230
    Open Access
    Review
    Negative environmental influences on the developing brain mediated by epigenetic modifications
    Brain development, a complex process, consisting of several phases, starting as early as two weeks after conception, and continuing through childhood till early adolescence, is crucial for the devel [...] Read more.
    Maya Komar-Fletcher ... Joanna Michalina Jurek
    Published: September 28, 2023 Explor Neurosci. 2023;2:193–211
    DOI: https://doi.org/10.37349/en.2023.00021
    View:12158
    Download:135
    Open Access
    Review
    Effects mediated by melatonin and cortisol of artificial light and noise, alone and in combination, on sleep and health
    As an integral part of human chronobiology, the circadian system plays a crucial role in regulating key biological functions, including sleep and the intricate hormonal rhythms of melatonin (MLT) an [...] Read more.
    Nahum M. Gabinet
    Published: September 13, 2024 Explor Neurosci. 2024;3:382–417
    DOI: https://doi.org/10.37349/en.2024.00057
    This article belongs to the special issue Circadian Rhythm and Melatonin
    View:9862
    Download:74
    Open Access
    Review
    Impact of circadian clock dysfunction on human health
    All living organisms exhibit circadian rhythms. Humans show circadian rhythm of the different physiological functions such as sleep-wake cycle, core body temperature, feeding behavior, metabolic act [...] Read more.
    Saptadip Samanta, Sk Asif Ali
    Published: September 29, 2022 Explor Neurosci. 2022;1:4–30
    DOI: https://doi.org/10.37349/en.2022.00002
    This article belongs to the special issue Circadian Rhythm and Melatonin
    View:9702
    Download:162
    Open Access
    Review
    Stigma and psychosocial problems in patients with epilepsy
    Epilepsy, a prevalent neurological disorder, is characterized by chronic seizures resulting from abnormal electrical activity in the brain. Adequate medical treatment allows roughly 70% of patients  [...] Read more.
    Kubra Yeni
    Published: December 06, 2023 Explor Neurosci. 2023;2:251–263
    DOI: https://doi.org/10.37349/en.2023.00026
    This article belongs to the special issue Epilepsy
    View:8096
    Download:168
    Open Access
    Review
    Update for astrocytomas: medical and surgical management considerations
    Astrocytomas include a wide range of tumors with unique mutations and varying grades of malignancy. These tumors all originate from the astrocyte, a star-shaped glial cell that plays a major role in [...] Read more.
    Matthew Willman ... Brandon Lucke-Wold
    Published: February 23, 2023 Explor Neurosci. 2023;2:1–26
    DOI: https://doi.org/10.37349/en.2023.00009
    View:7751
    Download:98
    Open Access
    Mini Review
    Nutritional treatment with the ketogenic diet in children with refractory epilepsy: a narrative review
    The two mainstays of therapy for refractory epilepsy are medication and surgery. Child behavioral and cognitive aspects of epilepsy can be improved by using a specialized dietary regimen such as the [...] Read more.
    Srilaxmi Vityala ... Swathi Nenavath
    Published: October 30, 2023 Explor Neurosci. 2023;2:245–250
    DOI: https://doi.org/10.37349/en.2023.00025
    This article belongs to the special issue Epilepsy
    View:4210
    Download:665
    Open Access
    Review
    Current therapeutics for Alzheimer’s disease and clinical trials
    Alzheimer’s disease (AD) is a major type of dementia and neurodegenerative disease, characterized by memory loss and cognitive decline. Over decades, significant efforts have been dedicated to fin [...] Read more.
    Danqing Xiao, Chen Zhang
    Published: June 27, 2024 Explor Neurosci. 2024;3:255–271
    DOI: https://doi.org/10.37349/en.2024.00048
    This article belongs to the special issue Alzheimer’s Disease
    View:14065
    Download:230
    Open Access
    Review
    Stigma and psychosocial problems in patients with epilepsy
    Epilepsy, a prevalent neurological disorder, is characterized by chronic seizures resulting from abnormal electrical activity in the brain. Adequate medical treatment allows roughly 70% of patients  [...] Read more.
    Kubra Yeni
    Published: December 06, 2023 Explor Neurosci. 2023;2:251–263
    DOI: https://doi.org/10.37349/en.2023.00026
    This article belongs to the special issue Epilepsy
    View:8096
    Download:168
    Open Access
    Review
    Impact of circadian clock dysfunction on human health
    All living organisms exhibit circadian rhythms. Humans show circadian rhythm of the different physiological functions such as sleep-wake cycle, core body temperature, feeding behavior, metabolic act [...] Read more.
    Saptadip Samanta, Sk Asif Ali
    Published: September 29, 2022 Explor Neurosci. 2022;1:4–30
    DOI: https://doi.org/10.37349/en.2022.00002
    This article belongs to the special issue Circadian Rhythm and Melatonin
    View:9702
    Download:162
    Open Access
    Review
    Negative environmental influences on the developing brain mediated by epigenetic modifications
    Brain development, a complex process, consisting of several phases, starting as early as two weeks after conception, and continuing through childhood till early adolescence, is crucial for the devel [...] Read more.
    Maya Komar-Fletcher ... Joanna Michalina Jurek
    Published: September 28, 2023 Explor Neurosci. 2023;2:193–211
    DOI: https://doi.org/10.37349/en.2023.00021
    View:12158
    Download:135
    Open Access
    Mini Review
    Neuroprotective compounds from three common medicinal plants of West Bengal, India: a mini review
    Neural disorders refer to conditions of the nervous system due to infection or degeneration of the neurons leading to either neurodegenerative disorder or neuropsychiatric disorder. Some such disord [...] Read more.
    Suvendu Ghosh ... Debosree Ghosh
    Published: December 26, 2023 Explor Neurosci. 2023;2:307–317
    DOI: https://doi.org/10.37349/en.2023.00030
    This article belongs to the special issue Medicinal Plants and Bioactive Phytochemicals in Neuroprotection
    View:7215
    Download:125
    Open Access
    Review
    Stigma and psychosocial problems in patients with epilepsy
    Epilepsy, a prevalent neurological disorder, is characterized by chronic seizures resulting from abnormal electrical activity in the brain. Adequate medical treatment allows roughly 70% of patients  [...] Read more.
    Kubra Yeni
    Published: December 06, 2023 Explor Neurosci. 2023;2:251–263
    DOI: https://doi.org/10.37349/en.2023.00026
    This article belongs to the special issue Epilepsy
    View:8096
    Download:168
    Open Access
    Review
    Neuropharmacologic modulation of the melatonergic system
    The circadian rhythm is a critical system that governs an organism’s functions in alignment with the light-dark cycle. Melatonin release from the pineal gland plays a crucial role in regulating th [...] Read more.
    Utku Aykan ... Canan Uluoglu
    Published: December 22, 2023 Explor Neurosci. 2023;2:287–306
    DOI: https://doi.org/10.37349/en.2023.00029
    This article belongs to the special issue Circadian Rhythm and Melatonin
    View:7019
    Download:65
    Open Access
    Review
    Updates in mechanical thrombectomy
    Stroke is a leading cause of morbidity and mortality. The advent of mechanical thrombectomy has largely improved patient outcomes. This article reviews the features and outcomes associated with aspi [...] Read more.
    Kevin Pierre ... Brandon Lucke-Wold
    Published: December 30, 2022 Explor Neurosci. 2022;1:83–99
    DOI: https://doi.org/10.37349/en.2022.00007
    View:5378
    Download:90
    Open Access
    Review
    Update for astrocytomas: medical and surgical management considerations
    Astrocytomas include a wide range of tumors with unique mutations and varying grades of malignancy. These tumors all originate from the astrocyte, a star-shaped glial cell that plays a major role in [...] Read more.
    Matthew Willman ... Brandon Lucke-Wold
    Published: February 23, 2023 Explor Neurosci. 2023;2:1–26
    DOI: https://doi.org/10.37349/en.2023.00009
    View:7751
    Download:98
    Open Access
    Review
    Impact of circadian clock dysfunction on human health
    All living organisms exhibit circadian rhythms. Humans show circadian rhythm of the different physiological functions such as sleep-wake cycle, core body temperature, feeding behavior, metabolic act [...] Read more.
    Saptadip Samanta, Sk Asif Ali
    Published: September 29, 2022 Explor Neurosci. 2022;1:4–30
    DOI: https://doi.org/10.37349/en.2022.00002
    This article belongs to the special issue Circadian Rhythm and Melatonin
    View:9702
    Download:162
    Open Access
    Review
    Neuroprotective prospectives of triterpenoids
    Neurological disorders including neurodegenerative disorders continue to pose significant therapeutic challenges. Triterpenoids, a diverse group of natural compounds found abundantly in plants, poss [...] Read more.
    Apoorva A. Bankar ... Nazma N. Inamdar
    Published: June 26, 2024 Explor Neurosci. 2024;3:231–254
    DOI: https://doi.org/10.37349/en.2024.00047
    This article belongs to the special issue Medicinal Plants and Bioactive Phytochemicals in Neuroprotection
    View:2331
    Download:54
    Special Issues
    From the Editor-in-Chief
    It is a great pleasure to serve as the newly appointed Editor-in-Chief of Exploration of Neuroscience (EN). EN will be a strong platform for the publication of groundshaking, cutting edge science that will expand our knowledge of neurological diseases and disease treatment. Advances in molecular, cellular and system neurosciences have greatly expanded our understanding of the healthy and the injured brain in recent years, which has set up fascinating perspectives for the development of new treatment options. With the infrastructures and support of Open Exploration Publishing services, the new EN journal seeks to become a reference in discovery and education in neurological diseases.
    Dirk M. Hermann
    Editor-in-Chief of Exploration of Neuroscience