• Exploration of Neuroscience

    eISSN: 2834-5347
    EiC: Dirk M. Hermann, MD, University of Duisburg-Essen
    Frequency: Bimonthly
    APC: No Article Processing Charge
    Publishing Model: Open Access
    Peer Review Model: Single Blind
    Indexing & Archiving: Portico
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    Articles
    Open Access
    Review
    Cellular and molecular mechanisms of stress-induced memory impairment
    Exposure to stressful conditions plays a critical role in brain processes, including neural plasticity, synaptic transmission, and cognitive functions. Since memory-related brain regions, the hippocampus (Hip), the amygdala, and t [...] Read more.
    Ameneh Rezayof ... Shiva Hashemizadeh
    Published: December 30, 2022 Explor Neurosci. 2022;1:100–119
    DOI: https://doi.org/10.37349/en.2022.00008
    This article belongs to the special issue Neuroinflammation in the Ageing and the Injured Brain
    View:120
    Download:19
    Times Cited: 0
    Open Access
    Review
    Updates in mechanical thrombectomy
    Stroke is a leading cause of morbidity and mortality. The advent of mechanical thrombectomy has largely improved patient outcomes. This article reviews the features and outcomes associated with aspi [...] Read more.
    Kevin Pierre ... Brandon Lucke-Wold
    Published: December 30, 2022 Explor Neurosci. 2022;1:83–99
    DOI: https://doi.org/10.37349/en.2022.00007
    This article belongs to the special issue Emerging Trends in Endovascular Management
    View:148
    Download:23
    Times Cited: 0
    Open Access
    Perspective
    Should we rethink neurodegeneration?
    The therapy of many neurological disorders has advanced markedly during recent decades. Not so for neurodegenerative disorders. Early detection, deep individual genotyping and phenotyping, and perso [...] Read more.
    Jussi O. T. Sipilä
    Published: December 26, 2022 Explor Neurosci. 2022;1:75–82
    DOI: https://doi.org/10.37349/en.2022.00006
    View:126
    Download:14
    Times Cited: 0
    Open Access
    Review
    Neuroprotective and neurorestorative actions of mesenchymal stromal cell-derived small extracellular vesicles in the ischemic brain
    Ischemic stroke is a highly prevalent condition that frequently results in life-long disability and death. Considerable efforts have been made to establish treatments that prevent secondary ischemic [...] Read more.
    Chen Wang ... Dirk M. Hermann
    Published: October 09, 2022 Explor Neurosci. 2022;1:61–74
    DOI: https://doi.org/10.37349/en.2022.00005
    This article belongs to the special issue Extracellular Vesicles as Cell-based Therapeutics
    View:399
    Download:26
    Times Cited: 0
    Open Access
    Perspective
    Recent developments and future perspectives of neuropathology
    This brief statement describes some recent achievements of neuropathological research, with the focus on Alzheimer’s and other age-related diseases, neurodegenerative disorders (tauopathies, synucleinopathies), multimorbidity of [...] Read more.
    Kurt A. Jellinger
    Published: September 30, 2022 Explor Neurosci. 2022;1:54–60
    DOI: https://doi.org/10.37349/en.2022.00004
    View:350
    Download:36
    Times Cited: 0
    Open Access
    Review
    Neuregulins: subcellular localization, signaling pathways and their relationship with neuroplasticity and neurological diseases
    Neuregulins (NRGs) and their cognate ErbB receptors (ErbB2–ErbB4) constitute a vast group of proteins encoded by six different genes (NRG16) and many isoforms with critical  [...] Read more.
    Marines Longart ... Juan Carlos Martínez
    Published: September 29, 2022 Explor Neurosci. 2022;1:31–53
    DOI: https://doi.org/10.37349/en.2022.00003
    Open Access
    Editorial
    Cutting edges in neuroscience to exceed borders
    Dirk M. Hermann
    Published: September 01, 2022 Explor Neurosci. 2022;1:1–3
    DOI: https://doi.org/10.37349/en.2022.00001
    View:530
    Download:40
    Times Cited: 0
    Open Access
    Review
    Impact of circadian clock dysfunction on human health
    All living organisms exhibit circadian rhythms. Humans show circadian rhythm of the different physiological functions such as sleep-wake cycle, core body temperature, feeding behavior, metabolic act [...] Read more.
    Saptadip Samanta, Sk Asif Ali
    Published: September 29, 2022 Explor Neurosci. 2022;1:4–30
    DOI: https://doi.org/10.37349/en.2022.00002
    This article belongs to the special issue Circadian Rhythm and Melatonin
    View:430
    Download:16
    Times Cited: 0
    Open Access
    Review
    Neuroprotective and neurorestorative actions of mesenchymal stromal cell-derived small extracellular vesicles in the ischemic brain
    Ischemic stroke is a highly prevalent condition that frequently results in life-long disability and death. Considerable efforts have been made to establish treatments that prevent secondary ischemic [...] Read more.
    Chen Wang ... Dirk M. Hermann
    Published: October 09, 2022 Explor Neurosci. 2022;1:61–74
    DOI: https://doi.org/10.37349/en.2022.00005
    This article belongs to the special issue Extracellular Vesicles as Cell-based Therapeutics
    View:399
    Download:26
    Times Cited: 0
    Open Access
    Perspective
    Recent developments and future perspectives of neuropathology
    This brief statement describes some recent achievements of neuropathological research, with the focus on Alzheimer’s and other age-related diseases, neurodegenerative disorders (tauopathies, synucleinopathies), multimorbidity of [...] Read more.
    Kurt A. Jellinger
    Published: September 30, 2022 Explor Neurosci. 2022;1:54–60
    DOI: https://doi.org/10.37349/en.2022.00004
    View:350
    Download:36
    Times Cited: 0
    Open Access
    Review
    Neuregulins: subcellular localization, signaling pathways and their relationship with neuroplasticity and neurological diseases
    Neuregulins (NRGs) and their cognate ErbB receptors (ErbB2–ErbB4) constitute a vast group of proteins encoded by six different genes (NRG16) and many isoforms with critical  [...] Read more.
    Marines Longart ... Juan Carlos Martínez
    Published: September 29, 2022 Explor Neurosci. 2022;1:31–53
    DOI: https://doi.org/10.37349/en.2022.00003
    Open Access
    Review
    Updates in mechanical thrombectomy
    Stroke is a leading cause of morbidity and mortality. The advent of mechanical thrombectomy has largely improved patient outcomes. This article reviews the features and outcomes associated with aspi [...] Read more.
    Kevin Pierre ... Brandon Lucke-Wold
    Published: December 30, 2022 Explor Neurosci. 2022;1:83–99
    DOI: https://doi.org/10.37349/en.2022.00007
    This article belongs to the special issue Emerging Trends in Endovascular Management
    View:148
    Download:23
    Times Cited: 0
    Open Access
    Editorial
    Cutting edges in neuroscience to exceed borders
    Dirk M. Hermann
    Published: September 01, 2022 Explor Neurosci. 2022;1:1–3
    DOI: https://doi.org/10.37349/en.2022.00001
    View:530
    Download:40
    Times Cited: 0
    Open Access
    Perspective
    Recent developments and future perspectives of neuropathology
    This brief statement describes some recent achievements of neuropathological research, with the focus on Alzheimer’s and other age-related diseases, neurodegenerative disorders (tauopathies, synucleinopathies), multimorbidity of [...] Read more.
    Kurt A. Jellinger
    Published: September 30, 2022 Explor Neurosci. 2022;1:54–60
    DOI: https://doi.org/10.37349/en.2022.00004
    View:350
    Download:36
    Times Cited: 0
    Open Access
    Review
    Neuroprotective and neurorestorative actions of mesenchymal stromal cell-derived small extracellular vesicles in the ischemic brain
    Ischemic stroke is a highly prevalent condition that frequently results in life-long disability and death. Considerable efforts have been made to establish treatments that prevent secondary ischemic [...] Read more.
    Chen Wang ... Dirk M. Hermann
    Published: October 09, 2022 Explor Neurosci. 2022;1:61–74
    DOI: https://doi.org/10.37349/en.2022.00005
    This article belongs to the special issue Extracellular Vesicles as Cell-based Therapeutics
    View:399
    Download:26
    Times Cited: 0
    Open Access
    Review
    Neuregulins: subcellular localization, signaling pathways and their relationship with neuroplasticity and neurological diseases
    Neuregulins (NRGs) and their cognate ErbB receptors (ErbB2–ErbB4) constitute a vast group of proteins encoded by six different genes (NRG16) and many isoforms with critical  [...] Read more.
    Marines Longart ... Juan Carlos Martínez
    Published: September 29, 2022 Explor Neurosci. 2022;1:31–53
    DOI: https://doi.org/10.37349/en.2022.00003
    Open Access
    Review
    Updates in mechanical thrombectomy
    Stroke is a leading cause of morbidity and mortality. The advent of mechanical thrombectomy has largely improved patient outcomes. This article reviews the features and outcomes associated with aspi [...] Read more.
    Kevin Pierre ... Brandon Lucke-Wold
    Published: December 30, 2022 Explor Neurosci. 2022;1:83–99
    DOI: https://doi.org/10.37349/en.2022.00007
    This article belongs to the special issue Emerging Trends in Endovascular Management
    View:148
    Download:23
    Times Cited: 0
    Open Access
    Review
    Cellular and molecular mechanisms of stress-induced memory impairment
    Exposure to stressful conditions plays a critical role in brain processes, including neural plasticity, synaptic transmission, and cognitive functions. Since memory-related brain regions, the hippocampus (Hip), the amygdala, and t [...] Read more.
    Ameneh Rezayof ... Shiva Hashemizadeh
    Published: December 30, 2022 Explor Neurosci. 2022;1:100–119
    DOI: https://doi.org/10.37349/en.2022.00008
    This article belongs to the special issue Neuroinflammation in the Ageing and the Injured Brain
    View:120
    Download:19
    Times Cited: 0
    Open Access
    Review
    Neuregulins: subcellular localization, signaling pathways and their relationship with neuroplasticity and neurological diseases
    Neuregulins (NRGs) and their cognate ErbB receptors (ErbB2–ErbB4) constitute a vast group of proteins encoded by six different genes (NRG16) and many isoforms with critical  [...] Read more.
    Marines Longart ... Juan Carlos Martínez
    Published: September 29, 2022 Explor Neurosci. 2022;1:31–53
    DOI: https://doi.org/10.37349/en.2022.00003
    Open Access
    Editorial
    Cutting edges in neuroscience to exceed borders
    Dirk M. Hermann
    Published: September 01, 2022 Explor Neurosci. 2022;1:1–3
    DOI: https://doi.org/10.37349/en.2022.00001
    View:530
    Download:40
    Times Cited: 0
    Open Access
    Review
    Impact of circadian clock dysfunction on human health
    All living organisms exhibit circadian rhythms. Humans show circadian rhythm of the different physiological functions such as sleep-wake cycle, core body temperature, feeding behavior, metabolic act [...] Read more.
    Saptadip Samanta, Sk Asif Ali
    Published: September 29, 2022 Explor Neurosci. 2022;1:4–30
    DOI: https://doi.org/10.37349/en.2022.00002
    This article belongs to the special issue Circadian Rhythm and Melatonin
    View:430
    Download:16
    Times Cited: 0
    Open Access
    Perspective
    Recent developments and future perspectives of neuropathology
    This brief statement describes some recent achievements of neuropathological research, with the focus on Alzheimer’s and other age-related diseases, neurodegenerative disorders (tauopathies, synucleinopathies), multimorbidity of [...] Read more.
    Kurt A. Jellinger
    Published: September 30, 2022 Explor Neurosci. 2022;1:54–60
    DOI: https://doi.org/10.37349/en.2022.00004
    View:350
    Download:36
    Times Cited: 0
    Open Access
    Review
    Neuroprotective and neurorestorative actions of mesenchymal stromal cell-derived small extracellular vesicles in the ischemic brain
    Ischemic stroke is a highly prevalent condition that frequently results in life-long disability and death. Considerable efforts have been made to establish treatments that prevent secondary ischemic [...] Read more.
    Chen Wang ... Dirk M. Hermann
    Published: October 09, 2022 Explor Neurosci. 2022;1:61–74
    DOI: https://doi.org/10.37349/en.2022.00005
    This article belongs to the special issue Extracellular Vesicles as Cell-based Therapeutics
    View:399
    Download:26
    Times Cited: 0
    Open Access
    Perspective
    Should we rethink neurodegeneration?
    The therapy of many neurological disorders has advanced markedly during recent decades. Not so for neurodegenerative disorders. Early detection, deep individual genotyping and phenotyping, and perso [...] Read more.
    Jussi O. T. Sipilä
    Published: December 26, 2022 Explor Neurosci. 2022;1:75–82
    DOI: https://doi.org/10.37349/en.2022.00006
    View:126
    Download:14
    Times Cited: 0
    Special Issues
    From the Editor-in-Chief
    It is a great pleasure to serve as the newly appointed Editor-in-Chief of Exploration of Neuroscience (EN). EN will be a strong platform for the publication of groundshaking, cutting edge science that will expand our knowledge of neurological diseases and disease treatment. Advances in molecular, cellular and system neurosciences have greatly expanded our understanding of the healthy and the injured brain in recent years, which has set up fascinating perspectives for the development of new treatment options. With the infrastructures and support of Open Exploration Publishing services, the new EN journal seeks to become a reference in discovery and education in neurological diseases.
    Dirk M. Hermann
    Editor-in-Chief of Exploration of Neuroscience