• About the Journal
    Exploration of Medicine (eISSN 2692-3106), a peer-reviewed, open access online journal, publishes articles that provide substantial and novel insights into medicine. The journal also welcomes submissions concerning the molecular and cell biological research of all human diseases. Submissions with good originality, well-designed experiments and rigorous data are particularly welcomed.
    From the Editor-in-Chief
    Medical research is becoming increasingly multi-disciplinary and molecular in scope, yet well-grounded clinical research is essential to understanding the relationship of molecular mechanisms with disease states and for the development of precision medicine. Exploration of Medicine seeks to report on research consistent with these trends and will fill an important niche that fosters the exchange of ideas and results among researchers across medical specialties. We welcome high quality papers that do not require major revisions resulting in fast publication times. We hope you enjoy Exploration of Medicine and look forward to receiving your submissions.
    Lindsay A. Farrer
    Editor-in-Chief of Exploration of Medicine
    Latest Articles
    Open Access
    The therapeutic potential of C-C chemokine receptor antagonists in nonalcoholic steatohepatitis
    Pooled prevalence of nonalcoholic fatty liver disease (NAFLD) globally is about 25%. Nonalcoholic steatohepatitis (NASH) with advanced fibrosis has been linked with substantial morbidity...
    Michael Doulberis ... Stergios A. Polyzos
    Online First: July 02, 2020 Explor Med. 2020;1:Online First
    DOI: https://doi.org/10.37349/emed.2020.00012
    This article belongs to the special issue Exploring NAFLD/NASH
    Open Access
    Nonalcoholic fatty liver disease and portal hypertension
    Nonalcoholic fatty liver disease (NAFLD) is a substantial and growing problem worldwide and has become the second most common indication for liver transplantation as it may progress to cirrhosis and...
    Marvin Ryou ... Gyorgy Baffy
    Published: June 29, 2020 Explor Med. 2020;1:149-169
    DOI: https://doi.org/10.37349/emed.2020.00011
    This article belongs to the special issue Exploring NAFLD/NASH
    Open Access
    Original Article
    Reduction of endoglin receptor impairs mononuclear cell-migration
    Aim: To test if the impairment of mononuclear cell (MNC) migration in patients with hereditary hemorrhagic telangiectasia (HHT) is due to the reduction of the endoglin (ENG) receptor on the cell su...
    Zhenying Han ... Hua Su
    Published: June 29, 2020 Explor Med. 2020;1:136-148
    DOI: https://doi.org/10.37349/emed.2020.00010
    Open Access
    Original Article
    Placental OPRM1 DNA methylation and associations with neonatal opioid withdrawal syndrome, a pilot study
    Aims: Epigenetic variation of DNA methylation of the mu-opioid receptor gene (OPRM1) has been identified in the blood and saliva of individuals with opioid use disorder (OUD) and infants with neona...
    Elisha M. Wachman ... Huiping Zhang
    Published: June 29, 2020 Explor Med. 2020;1:124-135
    DOI: https://doi.org/10.37349/emed.2020.00009
    This article belongs to the special issue The Biological Basis of Substance Use Disorders