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  • Exploration of Medicine

    eISSN: 2692-3106
    EiC: Lindsay A. Farrer, PhD, Boston University School of Medicine
    Frequency: Bimonthly
    APC: No Article Processing Charge
    Publishing Model: Open Access
    Peer Review Model: Single Blind
    Permanent Archive: Portico
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    Open Access
    Review
    Silent coronary artery disease in type 2 diabetes: a narrative review on epidemiology, risk factors, and clinical studies
    Silent coronary artery disease (CAD) is one of the manifestations of heart disease that particularly affects subjects with type 2 diabetes mellitus (T2DM). From a clinical point of view, silent CAD ...
    Saula Vigili de Kreutzenberg
    Online First: January 04, 2021 Explor Med. 2021;2:Online First
    DOI: https://doi.org/10.37349/emed.2021.00029
    This article belongs to the special issue Exploring Type 2 Diabetes Mellitus
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    This commentary is the product of a concerted effort to understand the needs, barriers, and gaps in the field of speech and language biomarkers for Alzheimer’s disease (AD). It distills interviews, surveys, and extensive correspondence with global leaders in the areas of dementia research, clinical trials, linguistics, and data analytics into an idealized clinical-study design for the harmonized collection of voice recordings. The ultimate goal of the effort is to democratize the ongoing speech and language analytics efforts by making such rich datasets available to the wider research ecosystem.

    Open Access
    Original Article
    Detection of mild traumatic brain injury in pediatric populations using BrainCheck, a tablet-based cognitive testing software: a preliminary study
    Aim: Despite its high frequency of occurrence, mild traumatic brain injury (mTBI), or concussion, is difficult to recognize and diagnose, particularly in pediatric populations. Conventional methods...
    Siao Ye ... Reza Hosseini Ghomi
    Published: December 31, 2020 Explor Med. 2020;1:396-405
    DOI: https://doi.org/10.37349/emed.2020.00027
    This article belongs to the special issue Digital Biomarkers: The New Frontier for Medicine and Research
    Abstract
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    View:96
    Download:7
    Times Cited: 0

    This commentary is the product of a concerted effort to understand the needs, barriers, and gaps in the field of speech and language biomarkers for Alzheimer’s disease (AD). It distills interviews, surveys, and extensive correspondence with global leaders in the areas of dementia research, clinical trials, linguistics, and data analytics into an idealized clinical-study design for the harmonized collection of voice recordings. The ultimate goal of the effort is to democratize the ongoing speech and language analytics efforts by making such rich datasets available to the wider research ecosystem.

    Open Access
    Original Article
    Identification of digital voice biomarkers for cognitive health
    Aim: Human voice contains rich information. Few longitudinal studies have been conducted to investigate the potential of voice to monitor cognitive health. The objective of this study is to identif...
    Honghuang Lin ... Rhoda Au
    Published: December 31, 2020 Explor Med. 2020;1:406-417
    DOI: https://doi.org/10.37349/emed.2020.00028
    This article belongs to the special issue Digital Biomarkers: The New Frontier for Medicine and Research
    Abstract
    Full Text
    PDF
    View:127
    Download:3
    Times Cited: 0

    This commentary is the product of a concerted effort to understand the needs, barriers, and gaps in the field of speech and language biomarkers for Alzheimer’s disease (AD). It distills interviews, surveys, and extensive correspondence with global leaders in the areas of dementia research, clinical trials, linguistics, and data analytics into an idealized clinical-study design for the harmonized collection of voice recordings. The ultimate goal of the effort is to democratize the ongoing speech and language analytics efforts by making such rich datasets available to the wider research ecosystem.

    Open Access
    Original Article
    Using machine intelligence to uncover Alzheimer’s disease progression heterogeneity
    Aim: Research suggests that Alzheimer’s disease (AD) is heterogeneous with numerous subtypes. Through a proprietary interactive ML system, several underlying biological mechanisms associa...
    Bessi Qorri ... Joseph Geraci
    Published: December 31, 2020 Explor Med. 2020;1:377-395
    DOI: https://doi.org/10.37349/emed.2020.00026
    This article belongs to the special issue Digital Biomarkers: The New Frontier for Medicine and Research
    Abstract
    Full Text
    PDF
    View:300
    Download:10
    Times Cited: 0

    This commentary is the product of a concerted effort to understand the needs, barriers, and gaps in the field of speech and language biomarkers for Alzheimer’s disease (AD). It distills interviews, surveys, and extensive correspondence with global leaders in the areas of dementia research, clinical trials, linguistics, and data analytics into an idealized clinical-study design for the harmonized collection of voice recordings. The ultimate goal of the effort is to democratize the ongoing speech and language analytics efforts by making such rich datasets available to the wider research ecosystem.

    Open Access
    Review
    The entero-insular axis: a journey in the physiopathology of diabetes
    Glycemic homeostasis is an essential mechanism for the proper working of an organism. However, balance in blood lipid and protein levels also plays an important role. The discovery of the hormone in...
    Roberta Malaguarnera ... Salvatore Piro
    Published: December 31, 2020 Explor Med. 2020;1:364-376
    DOI: https://doi.org/10.37349/emed.2020.00025
    This article belongs to the special issue Exploring Type 2 Diabetes Mellitus
    Abstract
    Full Text
    PDF
    View:169
    Download:9
    Times Cited: 0

    This commentary is the product of a concerted effort to understand the needs, barriers, and gaps in the field of speech and language biomarkers for Alzheimer’s disease (AD). It distills interviews, surveys, and extensive correspondence with global leaders in the areas of dementia research, clinical trials, linguistics, and data analytics into an idealized clinical-study design for the harmonized collection of voice recordings. The ultimate goal of the effort is to democratize the ongoing speech and language analytics efforts by making such rich datasets available to the wider research ecosystem.

    Open Access
    Commentary
    The need for a harmonized speech dataset for Alzheimer’s disease biomarker development
    This commentary is the product of a concerted effort to understand the needs, barriers, and gaps in the field of speech and language biomarkers for Alzheimer’s disease (AD). It distills in...
    Nicole L. Bjorklund ... Lampros Kourtis
    Published: December 31, 2020 Explor Med. 2020;1:359-363
    DOI: https://doi.org/10.37349/emed.2020.00024
    This article belongs to the special issue Digital Biomarkers: The New Frontier for Medicine and Research
    Abstract
    Full Text
    PDF
    View:309
    Download:17
    Times Cited: 0

    This commentary is the product of a concerted effort to understand the needs, barriers, and gaps in the field of speech and language biomarkers for Alzheimer’s disease (AD). It distills interviews, surveys, and extensive correspondence with global leaders in the areas of dementia research, clinical trials, linguistics, and data analytics into an idealized clinical-study design for the harmonized collection of voice recordings. The ultimate goal of the effort is to democratize the ongoing speech and language analytics efforts by making such rich datasets available to the wider research ecosystem.

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    Special Issues
    Ongoing Special Issues
    Exploring Chronic Liver Disease

    Dr. Amedeo Lonardo

    Submission Deadline: June 10, 2021

    Published Articles: 0

    Exploring Aortic Disease

    Dr. Kathleen G. Morgan

    Submission Deadline: February 10, 2021

    Published Articles: 0

    Nanomedicine and Cancer Immunotherapy

    Dr. Haijun Yu Dr. Yang Shi

    Submission Deadline: December 31, 2020

    Published Articles: 0

    Angiotensins—A Century of Progress

    Dr. Carlos M. Ferrario Dr. Leanne Groban

    Submission Deadline: December 31, 2020

    Published Articles: 0

    Exploring Type 2 Diabetes Mellitus

    Dr. Alessandro Mantovani Dr. Giovanni Targher

    Submission Deadline: July 31, 2020

    Published Articles: 5

    Digital Biomarkers: The New Frontier for Medicine and Research

    Dr. Rhoda Au

    Submission Deadline: June 20, 2020

    Published Articles: 5

    Exploring NAFLD/NASH

    Dr. Amedeo Lonardo Dr. Giovanni Targher

    Submission Deadline: June 01, 2020

    Published Articles: 9

    The Biological Basis of Substance Use Disorders

    Dr. Richard M. Sherva

    Submission Deadline: May 31, 2020

    Published Articles: 2

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    • Ongoing Special Issues
      Topic: Exploring Chronic Liver Disease Topic: Exploring Aortic Disease Topic: Nanomedicine and Cancer Immunotherapy Topic: Angiotensins—A Century of Progress Topic: Exploring Type 2 Diabetes Mellitus Topic: Digital Biomarkers: The New Frontier for Medicine and Research Topic: Exploring NAFLD/NASH Topic: The Biological Basis of Substance Use Disorders More
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      Current evidence and outcomes for retinopathy of prematurity prevention: insight into novel maternal and placental contributions View in PMC
    • Newsletter
      EM publisher joined Initiative for Open Abstracts
      Dec. 1, 2020
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      Nov. 30, 2020
      Welcome new Associate Editors
      Sep. 9, 2020
      EM listed in "Journals stating that they follow the ICMJE Recommendations"
      Aug. 26, 2020
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