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Open Access Case Report
Diagnosis of acute myocarditis with myocardial delayed enhancement on CTA: a case report
The diagnosis of acute myocarditis requires the exclusion of coronary artery disease (CAD). Coronary CTA (computed tomography angiography) is usually used to evaluate the coronary arteries in young patients. However, the use of coronary CTA for the diagnosis of myocarditis has been rarely reported. Here we present a Han male clinical myocarditis patient who was 18 years old, had a focus of enhancement in the subcardia, and predominantly involving the lateral wall of the left ventricle with iodinated contrast in coronary CTA. The patient was diagnosed with myocarditis. Immunoglobulin, vitamin C antioxidant, and myocardial nutrition were given to the patient for treatment. During follow-up, the patient’s myocardial enzymes gradually decreased to normal, and the original symptoms disappeared. As a non-invasive rapid examination method that can evaluate coronary artery and myocardial lesions at the same time, the utility of myocardial delayed enhancement on CTA may warrant further investigation.
Open Access Mini Review
Emerging insights into tricuspid valve disorders: epidemiology, clinical entities, innovations, and future perspectives
Tricuspid valve disorders (TVDs) have historically been underrecognized by clinicians. However, recent years have seen increasing awareness of their clinical impact. This mini-review aims to briefly highlight some questions regarding TVDs, such as Review of tricuspid valve disorders, Decoding its trends, The gender and racial divide, Breaking barriers, Where you live matters, Surgery vs. minimally invasive options, Bridging the gap, and the underappreciated significance of TVDs and why they’re becoming a growing concern in the U.S. There is a significant change in perception of the tricuspid valve—from being the “forgotten valve” to being an important area of focus in cardiology as well as clinical medicine in general. With the aid of advanced imaging methods like echocardiography, CT, and MRI that show a clear and three-dimensional view of the tricuspid valve, there is a better understanding of both the prevalence and diagnostic precision of TVDs. Advancements involving more efficient and optimally timed treatment strategies are also occurring. Although medical and surgical approaches are still in use, developments such as transcatheter tricuspid valve interventions (TTVIs) are promising, particularly for high-risk patients with minimal improvement with surgical treatment. TVDs, especially tricuspid regurgitation, have gained widespread attention in the medical and research community, resulting in improved and evolving diagnostic and therapeutic progress to improve patient outcomes.
Open Access Review
Comparison of short-term and long-term effects of peroral L-carnitine intake: clinical implications of elevated TMAO levels in cardiovascular complications
L-Carnitine (LC) is integral to energy production and fatty acid metabolism, facilitating the transport of long-chain fatty acids into mitochondria for β-oxidation. It modulates metabolic pathways, including pyruvate dehydrogenase activity, proteolysis, and protein synthesis, while also having anti-inflammatory and antioxidant characteristics. LC can be commonly applied to win the battle against HIV and cancer cachexia. Also, it can be recruited with the aim of improving physical and cognitive functions in athletes and the elderly. Despite these benefits, long-term LC administration has been associated to cardiovascular risks due its conversion to trimethylamine-N-oxide (TMAO) by the gut microbiota. Elevated TMAO levels are linked to atherosclerosis, oxidative stress, and an increased risk of cardiovascular disease, diabetes, and chronic kidney disease. Managing TMAO levels using dietary treatments and gut microbiota-targeting techniques, such as probiotics, may reduce these risks. This comprehensive review presents the state-of-the-art information on LC’s dual role, emphasizing the balance between its therapeutic potential and the risks of prolonged supplementation. It aims to guide clinicians and researchers in optimizing LC’s benefits while addressing its long term cardiovascular safety concerns.

Articles

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Open Access Review
Multimodality cardiac imaging and management of infective endocarditis: a review
Tess Calcagno ... Tom Kai Ming Wang
Published: November 19, 2025 Explor Cardiol. 2025;3:101282
631 46 0
Open Access Original Article
Burden of premature atrial contraction as a predictor of recurrence after atrial fibrillation ablation
Ruben Hoffmann ... Pieter Koopman
Published: November 13, 2025 Explor Cardiol. 2025;3:101281
854 39 0
Open Access Perspective
Lung water and coronary flow as complementary signals in aortic valve replacement
Marco Fabio Costantino ... Gianpaolo D’Addeo
Published: November 11, 2025 Explor Cardiol. 2025;3:101280
406 41 0
Open Access Review
Endothelial dysfunction and vascular stiffness: molecular drivers of cardiovascular aging
Muhammet Cihat Çelik ... Yusuf Karavelioğlu
Published: November 06, 2025 Explor Cardiol. 2025;3:101279
This article belongs to the special issue Molecular Mechanisms of Cardiovascular Aging
653 58 0
Open Access Systematic Review
Emerging cardiac CT biomarkers: a systematic review of diagnostic and prognostic utility in cardiovascular disease
Mubariz Ahmed Hassan ... Kimberly Delcour
Published: October 23, 2025 Explor Cardiol. 2025;3:101278
1398 73 0
Open Access Review
Why and when should be lipoprotein(a) level measured?
Miłosz Broncel, Marlena Broncel
Published: December 29, 2023 Explor Cardiol. 2023;1:180–192
18467 81 1
Open Access Review
Comparison of short-term and long-term effects of peroral L-carnitine intake: clinical implications of elevated TMAO levels in cardiovascular complications
Harsahaj Singh Wilkhoo ... Adnan Akhtar Shaikh
Published: February 10, 2025 Explor Cardiol. 2025;3:101250
17908 335 3
Open Access Editorial
Who is the author: genuine, honorary, ghost, gold, and fake authors?
Eugenio Picano
Published: May 13, 2024 Explor Cardiol. 2024;2:88–96
12066 205 7
Open Access Review
Oxidized low-density lipoproteins and their contribution to atherosclerosis
Abdullatif Taha Babakr
Published: January 17, 2025 Explor Cardiol. 2025;3:101246
This article belongs to the special issue Molecular Mechanisms of Cardiovascular Aging
11587 326 1
Open Access Review
B-lines by lung ultrasound in cardiology
Marco Antonio Rodrigues Torres, Natália Moraes de Quevedo
Published: November 14, 2024 Explor Cardiol. 2024;2:265–279
This article belongs to the special issue Multimodality Imaging in Ischemic Heart Disease
10686 267 2
Open Access Review
Mitral valve prolapse—arrhythmic faces of the valve disease
Maria Możdżan ... Karina Wierzbowska-Drabik
Published: October 31, 2023 Explor Cardiol. 2023;1:72–87
10566 267 1
Open Access Review
Echocardiographic Management of papillary muscle rupture during acute myocardial infarction
Paolo G. Pino ... Federico Nardi
Published: January 10, 2025 Explor Cardiol. 2025;3:101242
8573 347 0
Open Access Review
Comparison of short-term and long-term effects of peroral L-carnitine intake: clinical implications of elevated TMAO levels in cardiovascular complications
Harsahaj Singh Wilkhoo ... Adnan Akhtar Shaikh
Published: February 10, 2025 Explor Cardiol. 2025;3:101250
17908 335 3
Open Access Editorial
Who is a reviewer? The Good, the Bad, and the Ugly phenotypes
Eugenio Picano
Published: January 23, 2025 Explor Cardiol. 2025;3:101248
5784 330 0
Open Access Review
Oxidized low-density lipoproteins and their contribution to atherosclerosis
Abdullatif Taha Babakr
Published: January 17, 2025 Explor Cardiol. 2025;3:101246
This article belongs to the special issue Molecular Mechanisms of Cardiovascular Aging
11587 326 1
Open Access Review
Epigenetic mechanisms linking pregnancy complications to cardiovascular disease in offspring
Kazim Raza Talpur ... Muhammad Waleed Abdullah
Published: November 07, 2024 Explor Cardiol. 2024;2:241–252
5488 310 3
Open Access Editorial
Who is the author: genuine, honorary, ghost, gold, and fake authors?
Eugenio Picano
Published: May 13, 2024 Explor Cardiol. 2024;2:88–96
12066 205 7
Open Access Review
Noninvasive identification and therapeutic implications of supernormal left ventricular contractile phenotype
Yi Wang, Lixue Yin
Published: June 17, 2024 Explor Cardiol. 2024;2:97–113
4323 50 7
Open Access Review
Laboratory markers of metabolic syndrome
Filipa Morgado ... Leonel Pereira
Published: June 24, 2024 Explor Cardiol. 2024;2:114–133
This article belongs to the special issue Molecular Mechanisms of Cardiovascular Aging
9412 193 7
Open Access Original Article
Normal physiologic coronary flow velocity gradient across the left anterior descending artery in healthy asymptomatic subjects
Fausto Rigo ... Maurizio Agnoletto
Published: August 31, 2023 Explor Cardiol. 2023;1:42–48
4128 49 4
Open Access Review
Toxic metals in pregnancy and congenital heart defects. Insights and new perspectives for a technology-driven reduction in food sources
Francesca Gorini, Alessandro Tonacci
Published: November 13, 2023 Explor Cardiol. 2023;1:114–140
This article belongs to the special issue Environmental Cardiology
5654 61 4
Open Access Original Article
Nanoparticles loaded with the DNA methyltransferase inhibitor SGI-1027 decrease murine atherosclerosis and inflammation in cultured human macrophages
Ana Cristina Márquez-Sánchez ... Silvio Zaina
Published: April 10, 2024 Explor Cardiol. 2024;2:49–66
3897 45 4

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