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  • Exploration of Cardiology

    eISSN: 2994-5526
    EiC: Eugenio Picano, Italy
    Frequency: Continuous Publication
    APC: No Article Processing Charge before Jul 31, 2028
    Publishing Model: Open Access
    Peer Review Model: Single Blind
    Permanent Archive: Portico
    Indexing & Archiving: Google Scholar, Dimensions, Portico, etc.
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    Articles
    Open Access
    Case Report
    Left ventricular thrombus as a rare complication of pulmonary tuberculosis
    Tuberculosis (TB) continues to pose a significant public health burden in endemic regions, remaining a leading cause of morbidity and mortality. Although TB is associated with a range of complicatio [...] Read more.
    Amit Kumar ... Shweta Tanwar
    Published: April 29, 2025 Explor Cardiol. 2025;3:101255
    DOI: https://doi.org/10.37349/ec.2025.101255
    View:38
    Download:2
    Times Cited: 0
    Open Access
    Original Article
    Utility of myocardial work by echocardiography in the early diagnosis of cardiotoxicity
    Aims: Evaluate the role of myocardial work by echocardiography and determine its utility as an early diagnosis of cardiotoxicity. Methods: Single-center included 180 patients over 18 years  [...] Read more.
    Denise Cortes-Pérez ... Carlos Martínez-Hernández
    Published: April 27, 2025 Explor Cardiol. 2025;3:101254
    DOI: https://doi.org/10.37349/ec.2025.101254
    View:89
    Download:6
    Times Cited: 0
    Open Access
    Review
    The link between preterm birth and long-term cardiovascular risk: mechanisms, evidence, and vulnerable populations: a review
    Preterm birth, defined as delivery before 37 weeks of gestation, represents a global health concern linked to substantial cardiovascular risk later in life. Individuals born preterm, especially at e [...] Read more.
    Luisiana Stolfi ... Simona Pesce
    Published: April 22, 2025 Explor Cardiol. 2025;3:101253
    DOI: https://doi.org/10.37349/ec.2025.101253
    View:166
    Download:18
    Times Cited: 0
    Open Access
    Original Article
    Impact of tricuspid regurgitation on right ventricular myocardial work in patients with pulmonary hypertension: a pilot study
    Aim: Significant tricuspid regurgitation (TR) may be a confounding factor when assessing right ventricular (RV) function with imaging techniques. Global myocardial work (GMW) has been proposed as [...] Read more.
    Mauro Acquaro ... Stefano Ghio
    Published: April 22, 2025 Explor Cardiol. 2025;3:101252
    DOI: https://doi.org/10.37349/ec.2025.101252
    View:108
    Download:16
    Times Cited: 0
    Open Access
    Review
    Age-related atrial fibrillation: is there a role for the gut microbiome?
    Age-related atrial fibrillation (AF) is a common condition that has yet to be fully understood, with mechanisms to explain its development under investigation. Notably, cellular senescence, cardiac  [...] Read more.
    Michael Li ... Robert M. Lust
    Published: March 24, 2025 Explor Cardiol. 2025;3:101251
    DOI: https://doi.org/10.37349/ec.2025.101251
    This article belongs to the special issue Molecular Mechanisms of Cardiovascular Aging
    View:507
    Download:46
    Times Cited: 0
    Open Access
    Review
    Comparison of short-term and long-term effects of peroral L-carnitine intake: clinical implications of elevated TMAO levels in cardiovascular complications
    L-Carnitine (LC) is integral to energy production and fatty acid metabolism, facilitating the transport of long-chain fatty acids into mitochondria for β-oxidation. It modulates metabolic pathway [...] Read more.
    Harsahaj Singh Wilkhoo ... Adnan Akhtar Shaikh
    Published: February 10, 2025 Explor Cardiol. 2025;3:101250
    DOI: https://doi.org/10.37349/ec.2025.101250
    View:2379
    Download:115
    Times Cited: 0
    Open Access
    Editorial
    Who is the author: genuine, honorary, ghost, gold, and fake authors?
    While authorship practices can vary across different disciplines, authorship should reflect the individuals who have made a substantial contribution to the research project, take public [...] Read more.
    Eugenio Picano
    Published: May 13, 2024 Explor Cardiol. 2024;2:88–96
    DOI: https://doi.org/10.37349/ec.2024.00024
    View:8145
    Download:185
    Open Access
    Original Article
    Coronary external diameter index for assessing coronary artery involvement in Kawasaki disease
    Aim: Transthoracic echocardiography is commonly used to assess coronary artery dilatation in Kawasaki disease (KD). However, existing criteria often miss early abnormalities. This study examines  [...] Read more.
    Andrea Azzarelli ... Francesco Vierucci
    Published: October 31, 2023 Explor Cardiol. 2023;1:103–113
    DOI: https://doi.org/10.37349/ec.2023.00011
    View:4417
    Download:185
    Times Cited: 0
    Open Access
    Review
    Why and when should be lipoprotein(a) level measured?
    Lipoprotein(a) [Lp(a)] is composed of a low-density lipoprotein (LDL) and glycoprotein (a)—apo(a). The size and concentration of Lp(a) in serum can vary among individuals and is determined by gene [...] Read more.
    Miłosz Broncel, Marlena Broncel
    View:4417
    Download:42
    Times Cited: 0
    Open Access
    Review
    Mitral valve prolapse—arrhythmic faces of the valve disease
    Mitral valve prolapse (MVP) is a relatively common mitral valvulopathy and the most common cause of isolated primary mitral regurgitation (MR) requiring surgical repair. It affects about 1–3% of t [...] Read more.
    Maria Możdżan ... Karina Wierzbowska-Drabik
    View:4412
    Download:118
    Times Cited: 0
    Open Access
    Review
    Laboratory markers of metabolic syndrome
    Metabolic syndrome (MetS) is known as a non-communicable disease (NCD) that affects more and more individuals. MetS is closely related to type 2 diabetes mellitus (T2DM), cardiovascular disease (CVD [...] Read more.
    Filipa Morgado ... Leonel Pereira
    Published: June 24, 2024 Explor Cardiol. 2024;2:114–133
    DOI: https://doi.org/10.37349/ec.2024.00026
    This article belongs to the special issue Molecular Mechanisms of Cardiovascular Aging
    View:4041
    Download:113
    Open Access
    Review
    B-lines by lung ultrasound in cardiology
    Pulmonary congestion is a key determinant of heart failure, but for a long time it has been an elusive target for the clinical cardiologist in the pre-B-line era, despite research efforts of Carlo G [...] Read more.
    Marco Antonio Rodrigues Torres, Natália Moraes de Quevedo
    Published: November 14, 2024 Explor Cardiol. 2024;2:265–279
    DOI: https://doi.org/10.37349/ec.2024.00039
    This article belongs to the special issue Multimodality Imaging in Ischemic Heart Disease
    View:2857
    Download:152
    Times Cited: 0
    Open Access
    Original Article
    Coronary external diameter index for assessing coronary artery involvement in Kawasaki disease
    Aim: Transthoracic echocardiography is commonly used to assess coronary artery dilatation in Kawasaki disease (KD). However, existing criteria often miss early abnormalities. This study examines  [...] Read more.
    Andrea Azzarelli ... Francesco Vierucci
    Published: October 31, 2023 Explor Cardiol. 2023;1:103–113
    DOI: https://doi.org/10.37349/ec.2023.00011
    View:4417
    Download:185
    Times Cited: 0
    Open Access
    Editorial
    Who is the author: genuine, honorary, ghost, gold, and fake authors?
    While authorship practices can vary across different disciplines, authorship should reflect the individuals who have made a substantial contribution to the research project, take public [...] Read more.
    Eugenio Picano
    Published: May 13, 2024 Explor Cardiol. 2024;2:88–96
    DOI: https://doi.org/10.37349/ec.2024.00024
    View:8145
    Download:185
    Open Access
    Review
    Diagnostic modalities for ischemic heart disease: evaluating the role of stress echocardiography, cardiac CT, and myocardial perfusion scintigraphy in guiding coronary angiography
    Cardiovascular diseases, particularly ischemic heart disease (IHD), are the leading cause of mortality globally, accounting for 16% of deaths. Effective management of ischemic cardiomyopathy (ICM) i [...] Read more.
    Marco Fabio Costantino ... Luisiana Stolfi
    Published: January 13, 2025 Explor Cardiol. 2025;3:101243
    DOI: https://doi.org/10.37349/ec.2025.101243
    This article belongs to the special issue Multimodality Imaging in Ischemic Heart Disease
    View:2044
    Download:152
    Times Cited: 0
    Open Access
    Review
    B-lines by lung ultrasound in cardiology
    Pulmonary congestion is a key determinant of heart failure, but for a long time it has been an elusive target for the clinical cardiologist in the pre-B-line era, despite research efforts of Carlo G [...] Read more.
    Marco Antonio Rodrigues Torres, Natália Moraes de Quevedo
    Published: November 14, 2024 Explor Cardiol. 2024;2:265–279
    DOI: https://doi.org/10.37349/ec.2024.00039
    This article belongs to the special issue Multimodality Imaging in Ischemic Heart Disease
    View:2857
    Download:152
    Times Cited: 0
    Open Access
    Review
    Emerging technologies and applications in multimodality imaging for ischemic heart disease: current state and future of artificial intelligence
    Ischemic heart disease (IHD) is a major global health issue, frequently resulting in myocardial infarction and ischemic cardiomyopathy. Prompt and precise diagnosis is essential to avert complicatio [...] Read more.
    Praveen Kumar Chandra Sekar, Ramakrishnan Veerabathiran
    Published: November 11, 2024 Explor Cardiol. 2024;2:253–264
    DOI: https://doi.org/10.37349/ec.2024.00038
    This article belongs to the special issue Multimodality Imaging in Ischemic Heart Disease
    View:1597
    Download:145
    Times Cited: 0
    Open Access
    Editorial
    Who is a reviewer? The Good, the Bad, and the Ugly phenotypes
    By offering their expertise, reviewers help authors improve their work and also support editors in selecting high-quality studies, thereby reinforcing the integrity of scientific literature. Much li [...] Read more.
    Eugenio Picano
    Published: January 23, 2025 Explor Cardiol. 2025;3:101248
    DOI: https://doi.org/10.37349/ec.2025.101248
    View:1609
    Download:143
    Times Cited: 0
    Open Access
    Editorial
    Who is the author: genuine, honorary, ghost, gold, and fake authors?
    While authorship practices can vary across different disciplines, authorship should reflect the individuals who have made a substantial contribution to the research project, take public [...] Read more.
    Eugenio Picano
    Published: May 13, 2024 Explor Cardiol. 2024;2:88–96
    DOI: https://doi.org/10.37349/ec.2024.00024
    View:8145
    Download:185
    Open Access
    Commentary
    Low-doses ionizing radiation exposure: an emerging causal risk factor for cardiovascular disease
    Maria Grazia Andreassi
    Published: December 11, 2023 Explor Cardiol. 2023;1:141–147
    DOI: https://doi.org/10.37349/ec.2023.00013
    This article belongs to the special issue Environmental Cardiology
    View:1905
    Download:20
    Open Access
    Review
    Noninvasive identification and therapeutic implications of supernormal left ventricular contractile phenotype
    Left ventricular (LV) function is typically evaluated through LV ejection fraction (EF), a robust indicator of risk, showing a nonlinear increase in mortality rates below 40%. Conversely, [...] Read more.
    Yi Wang, Lixue Yin
    Published: June 17, 2024 Explor Cardiol. 2024;2:97–113
    DOI: https://doi.org/10.37349/ec.2024.00025
    View:1971
    Download:32
    Open Access
    Original Article
    Normal physiologic coronary flow velocity gradient across the left anterior descending artery in healthy asymptomatic subjects
    Aim: Coronary flow velocity (CFV) can be obtained with transthoracic echocardiography (TTE) in the left anterior descending coronary artery (LAD). The physiologic flow velocity gradient across th [...] Read more.
    Fausto Rigo ... Maurizio Agnoletto
    Published: August 31, 2023 Explor Cardiol. 2023;1:42–48
    DOI: https://doi.org/10.37349/ec.2023.00006
    View:2089
    Download:25
    Open Access
    Original Article
    Nanoparticles loaded with the DNA methyltransferase inhibitor SGI-1027 decrease murine atherosclerosis and inflammation in cultured human macrophages
    Aim: The DNA of the atheroma is hypermethylated relative to adjacent healthy vascular tissue. A significant portion of hypermethylated loci in the atheroma DNA map to genes related to macrophage  [...] Read more.
    Ana Cristina Márquez-Sánchez ... Silvio Zaina
    Published: April 10, 2024 Explor Cardiol. 2024;2:49–66
    DOI: https://doi.org/10.37349/ec.2024.00021
    View:1990
    Download:34
    Open Access
    Protocol
    Vascular senescence and atherosclerotic plaque vulnerability: investigating the telomere-mitochondria crosstalk—rationale and design of the VICTORIA Study
    Vascular aging is recognized as one of the hallmarks of atherosclerosis. Currently, a growing body of evidence suggests that there exists a mutual crosstalk between telomere dysfunction and mitochon [...] Read more.
    Jonica Campolo ... Maria Grazia Andreassi
    Published: July 24, 2024 Explor Cardiol. 2024;2:168–177
    DOI: https://doi.org/10.37349/ec.2024.00030
    This article belongs to the special issue Molecular Mechanisms of Cardiovascular Aging
    View:1389
    Download:23
    Special Issues
    From the Editor-in-Chief
    Exploration of Cardiology (EC) is a new open-access journal from Open Exploration publisher. The journal aims to provide, at this moment free of charge, an open forum for scholarly research on a range of topics. There are many good cardiology journals, with excellent editors, and still, one more journal may have a unique role in promoting research and debate in the new era of environmental cardiology and the obligatory quest for economic, legal, and environmental sustainability of cardiology practice. Healthcare money shortage and energy crisis, the pandemic pressure, climate change, and increasing evidence of environmental roots of cardiovascular disease pose new challenges to clinical cardiologists, researchers, and professional societies. Based on these principles, the EC will place a special emphasis on all techniques, methods, and practices promoting the development of ‘green’ (climate-neutral) and ‘blue’ (sustainable) cardiology. EC will publish Original Articles, Reviews, Protocols, Commentaries, Perspectives, and Editorials, and will also regularly publish special exploration issues to highlight advances at the cutting edge of research. I invite you to consider publishing your next paper with us and help us put EC in a prominent place in the cardiovascular editorial domains. As editor-in-Chief, I take a commitment to respecting the Author’s rights to fast and fair review and to do this in the best possible way with an inner team of associate editors who will work to serve our submitting authors, who are the real strength of any journal.
    Eugenio Picano
    Editor-in-Chief of Exploration of Cardiology