Contents
Special Issue Topic

Molecular Diagnostics in Oncology

Submission Deadline: July 31, 2025

Guest Editor

Prof. Evgeny Imyanitov E-Mail

Head of the Research Division of Tumor Growth Biology, N.N. Petrov Research Institute of Oncology, St. Petersburg, Russia

About the Special lssue

Molecular diagnostics has become an integral part of clinical oncology. There are several areas of its application, e.g., 1) Identification of subjects with hereditary cancer syndromes; 2) Molecular tests for personalization of cancer therapy; 3) Precision histological diagnosis based on subtype-specific tumor markers; 4) Determination of prognosis for cancer disease; 5) Non-invasive methods of early detection and monitoring of malignant clones. Recent invention of next generation sequencing has significantly revolutionized this field of cancer medicine. This Special Issue is devoted to recent advances in clinical cancer genetics, targeted therapy, liquid biopsy, relevant methods of DNA and RNA testing, and other related aspects of molecular medicine.

Keywords: Hereditary cancer syndromes, predictive markers, somatic mutations, liquid biopsy, next-generation sequencing (NGS)

Published Articles

Open Access Original Article
Vascular endothelial growth factor (VEGF) as a diagnostic marker of non-small cell lung cancer
Noor Mey Wardhani ... Bulkis Natsir
Published: May 28, 2025 Explor Med. 2025;6:1001327
401 9 0
Open Access Original Article
Analysis of SDC2 and SEPT9 promoters methylation in plasma cfDNA to detect colorectal and precancerous lesions
Viktoria Borobova ... Sergey Kovalenko
Published: May 21, 2025 Explor Med. 2025;6:1001322
322 8 0
Open Access Original Article
Prognostic value of HLA class I expression in patients with cutaneous melanoma and soft tissue sarcomas treated with cancer-testis antigens-based vaccine
Tatiana L. Nekhaeva ... Irina A. Baldueva
Published: February 27, 2025 Explor Med. 2025;6:1001287
706 30 0