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  • Special Issue Topic

    Exploration of 3D and 4D Printing in the Biomedical and Personalized Medicine Fields: Merits and Challenges

    Submission Deadline: August 31, 2023

    Guest Editor

    Dr. Nermeen A. Elkasabgy E-Mail

    Cairo University Faculty of Pharmacy, Cairo, Egypt

    Research Keywords: 3D printing; microfluidics; drug delivery; nanoplatforms; microparticles; sustained drug release; scaffolds; implants; tissue engineering; wound healing; brain targeting; pulmonary delivery; cancer; ocular delivery


    About the Special Issue

    3D printing, known as additive manufacturing, represents a breakthrough in the biomedical field. One of its prominent advantages is the compliance with the patients’ specific medical needs through paving a new track for personalized medicine. Personalized medicine is considered an innovated paradigm in the biomedical field. Personalized medicine means tailoring an individualized treatment for each disease, which in turn overcomes the limitations encountered from traditional medicine “one size fits all”. Avoiding severe side effects, enhancing the efficacy of drugs, saving time and cost as well as decreasing the failure rate of clinical experiments are all considered merits of personalized medicine.

    To construct a 3D print, several printers can be used like stereolithography, selective laser sintering, fused deposition modeling, etc.  3D printing can be efficiently used in fabricating medical devices with customized shapes and architectures like stents, wound dressing, limbs, etc. Additionally, 3D bioprinting has recently emerged as a magic option to develop tissue constructs capable of restoring lost or diseased tissues and minimizing the risk of tissue rejection by patients’ immune system.

    Fabricating 4D prints using stimuli responsive polymers capable of altering their shapes under the effect of external stimuli like light, temperature, electric or magnetic fields has opened new avenues for advances in tissue regeneration, drug delivery as well as biomedical devices fabrication.

    This special issue encourages researchers to submit their high quality research and review articles exploring the 3D and 4D printing in the biomedical and pharmaceutical fields.

    The Editors believe that this special issue of Exploration of Medicine will allow the scientific community to reflect how far we have advanced in the frontiers of knowledge, where accepted knowledge of the system may need revision, and target the new frontiers of discovery in reaching ultimate knowledge of how hormones act to both regulate and dysregulate body homeostasis.

    Keywords: 3D printing, 4D printing, personalized medicine, customized pharmaceutics, implants, scaffolds, medical devices, 3D bioprinting, stimuli-responsive polymers, shape memory polymers, 3D printers

    Call for Papers

    Published Articles

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    • Aims and Scope
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    • Ongoing Special Issues
      The Role of Repetitive DNA Elements in the Development and Progression of Human Disease
      Colon Controlled Microbiome Function: Role, Impact, Structure, Pathogenetic Significance, Therapeutic and Diagnostic Management
      The Role of Gut Microbiota and its Metabolites in Gastrointestinal Diseases
      Recent Advances in Hypertension
      Disease Diagnosis, Molecular Mechanism and Therapeutic Strategies in Kidney Injury and Fibrosis
      Perspectives on Causal Mechanisms, Prevention and Management of Pediatric Obesity and Related Comorbidities
      Beyond Weed: Clinical Applications of Cannabis and Cannabinoids
      The Biological Basis of Substance Use Disorders
      Nanomedicine and Cancer Immunotherapy
      Exploring Aortic Disease
      Cellular Models for In Vitro Modeling of Parkinson’s Disease
      Role of Microbiome in Ocular Diseases
      Advances in Wound Healing
      Determinants of Exceptional Longevity
      Genetic and Epigenetic Control of Autophagy in Human Diseases
      RNA World in Health and Disease
      Lung Fibrosis—Models and Mechanisms
      Exploration of 3D and 4D Printing in the Biomedical and Personalized Medicine Fields: Merits and Challenges
      Biomaterials and Biomarkers in Dentistry: Up to Date
      Gut Microbiota Derived Metabolites and Chronic Inflammatory Diseases
      Vitamin D—Current and the Future
      Emerging Infectious Diseases
      Applications of Radiomics in Precision Medicine
      Functional Biomaterials and Tumor Immunotherapy
      Breast Cancer: Basic and Clinical Advances
      Advances in the Identification and Mechanisms of Action of Luminal Compounds Involved in Inflammatory Bowel Diseases
      Drug Adherence in Hypertension
    • Completed Special Issues
      Exploring NAFLD/NASH
      Digital Biomarkers: The New Frontier for Medicine and Research
      Exploring Type 2 Diabetes Mellitus
      Angiotensins—A Century of Progress
      Exploring Chronic Liver Disease
      Reactive Oxygen Species (ROS) in Pathophysiological Conditions
      Techniques in Repurposing and Targeted Delivery: Bringing a New Life to Shelved Drugs
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