• Special Issue Topic

    Exploration of 3D and 4D Printing in the Biomedical and Personalized Medicine Fields: Merits and Challenges

    Submission Deadline: August 31, 2023

    Guest Editor

    Dr. Nermeen A. Elkasabgy E-Mail

    Cairo University Faculty of Pharmacy, Cairo, Egypt

    Research Keywords: 3D printing; microfluidics; drug delivery; nanoplatforms; microparticles; sustained drug release; scaffolds; implants; tissue engineering; wound healing; brain targeting; pulmonary delivery; cancer; ocular delivery

    About the Special Issue

    3D printing, known as additive manufacturing, represents a breakthrough in the biomedical field. One of its prominent advantages is the compliance with the patients’ specific medical needs through paving a new track for personalized medicine. Personalized medicine is considered an innovated paradigm in the biomedical field. Personalized medicine means tailoring an individualized treatment for each disease, which in turn overcomes the limitations encountered from traditional medicine “one size fits all”. Avoiding severe side effects, enhancing the efficacy of drugs, saving time and cost as well as decreasing the failure rate of clinical experiments are all considered merits of personalized medicine.

    To construct a 3D print, several printers can be used like stereolithography, selective laser sintering, fused deposition modeling, etc.  3D printing can be efficiently used in fabricating medical devices with customized shapes and architectures like stents, wound dressing, limbs, etc. Additionally, 3D bioprinting has recently emerged as a magic option to develop tissue constructs capable of restoring lost or diseased tissues and minimizing the risk of tissue rejection by patients’ immune system.

    Fabricating 4D prints using stimuli responsive polymers capable of altering their shapes under the effect of external stimuli like light, temperature, electric or magnetic fields has opened new avenues for advances in tissue regeneration, drug delivery as well as biomedical devices fabrication.

    This special issue encourages researchers to submit their high quality research and review articles exploring the 3D and 4D printing in the biomedical and pharmaceutical fields.

    The Editors believe that this special issue of Exploration of Medicine will allow the scientific community to reflect how far we have advanced in the frontiers of knowledge, where accepted knowledge of the system may need revision, and target the new frontiers of discovery in reaching ultimate knowledge of how hormones act to both regulate and dysregulate body homeostasis.

    Keywords: 3D printing, 4D printing, personalized medicine, customized pharmaceutics, implants, scaffolds, medical devices, 3D bioprinting, stimuli-responsive polymers, shape memory polymers, 3D printers

    Call for Papers

    Published Articles

    Open Access
    3D and 4D printing of biomedical materials: current trends, challenges, and future outlook
    Three-dimensional (3D) and four-dimensional (4D) printing have emerged as the next-generation fabrication technologies, covering a broad spectrum of areas, including construction, medicine, transpor [...] Read more.
    Gayan A. Appuhamillage ... Achintha Wijenayake
    Published: February 06, 2024 Explor Med. 2024;5:17–47
    DOI: https://doi.org/10.37349/emed.2024.00203
    Times Cited: 0
    Open Access
    Original Article
    Development of patient-specific 3D printed implants for total knee arthroplasty
    Aim: Arthritis is a degenerative condition characterized by the progressive deterioration of the knee joint, leading to aches, rigidity, and decreased mobility. Total knee arthroplasty (TKA) surg [...] Read more.
    Dasharath Ramavath ... Sudheer Reddy Devana
    Published: December 28, 2023 Explor Med. 2023;4:1033–1047
    DOI: https://doi.org/10.37349/emed.2023.00193
    Times Cited: 0
    Open Access
    3D printing in biomedicine: advancing personalized care through additive manufacturing
    The integration of three-dimensional (3D) printing techniques into the domains of biomedical research and personalized medicine highlights the evolving paradigm shifts within contemporary healthcare [...] Read more.
    Kalyani Pathak ... Barbie Borthakur
    Published: December 29, 2023 Explor Med. 2023;4:1135–1167
    DOI: https://doi.org/10.37349/emed.2023.00200
    Open Access
    Recent advances in the development of bioartificial pancreas using 3D bioprinting for the treatment of type 1 diabetes: a review
    Type 1 diabetes is a chronic condition that results from the destruction of insulin-producing β-cells in the pancreas. Current treatments for type 1 diabetes, such as insulin therapy and pancreatic [...] Read more.
    Anushikha Ghosh ... Abhik Mallick
    Published: December 06, 2023 Explor Med. 2023;4:886–922
    DOI: https://doi.org/10.37349/emed.2023.00184
    Open Access
    An overview of current advances and pharmaceutical uses of 3D and 4D printing
    The development of patient-specific prosthetics, medication administration, the manufacture of tissues and organs, and surgical planning have all benefited significantly from the use of three-dimens [...] Read more.
    Pankaj Sharma, Vinay Jain
    Published: August 31, 2023 Explor Med. 2023;4:560–575
    DOI: https://doi.org/10.37349/emed.2023.00161
    Times Cited: 0