• Special Issue Topic

    The Role of Gut Microbiota and its Metabolites in Gastrointestinal Diseases

    Submission Deadline: May 20, 2022

    Guest Editors

    Dr. Feng Tian E-Mail

    Department of Gastrointestinal Surgery, Shandong Provincial Hospital Affiliated to Shandong University; Shandong Provincial Hospital Affiliated to Shandong First Medical University, China

    Dr. Changqing Jing E-Mail

    Department of Gastrointestinal Surgery, Shandong Provincial Hospital Affiliated to Shandong University; Shandong Provincial Hospital Affiliated to Shandong First Medical University, China

    About the Special Issue

    Gut Microbiota (GM) is known as the second human genome. It is not only related to nutrition and metabolism, intestinal dysfunction, intestinal inflammation and immunity, and gastrointestinal tumors, but also can regulate the function of remote organs. The cross-talk between Gut Microbiota itself or its metabolites and intestinal cells plays an important role in the occurrence and development of gastrointestinal diseases. Although more and more diseases are confirmed to be related to Gut Microbiota, there are still many unknown areas worth exploring, including new discoveries of diseases, exploration of regulatory mechanisms, and evaluation of clinical interventions. Thus, we would like this special issue to focus on this area of Gut Microbiota and gastrointestinal diseases which remains under-appreciated.

    This special issue will include primary research papers and reviews. The content will range from a phenomenon description to their role in disease mechanism, with a primary focus on gastrointestinal diseases, and potential intervention evaluation in ameliorating human suffering.

    Keywords: gut microbiota, bacterial strain, gastrointestinal dysfunction, intestinal motility, nutrition and metabolism, gastrointestinal tumors

    Published Articles

    Open Access
    Original Article
    Comparison of eating habits and gut microbiota of preschool children with obesity
    Aim: Childhood obesity is a global health concern that affects the daily life of children. It has a complex pathogenesis that involves genetic and nutritional factors among others. Moreover, the  [...] Read more.
    Shymaa M. Al-Jabri ... Awatif A. Al-Judaibi
    Published: September 04, 2023 Explor Med. 2023;4:612–624
    DOI: https://doi.org/10.37349/emed.2023.00164
    Times Cited: 0
    Open Access
    The impact of COVID-19 pandemic on diagnosis and management of gastrointestinal cancers
    Gastrointestinal (GI) cancer is one of the leading causes of death that affect many patients around the world. The coronavirus disease 2019 (COVID-19) pandemic significantly impacted our healthcare  [...] Read more.
    Byung Soo Yoo ... David A. Johnson
    Published: June 28, 2023 Explor Med. 2023;4:356–362
    DOI: https://doi.org/10.37349/emed.2023.00147
    Times Cited: 0
    Open Access
    Gastrointestinal microbiome and coronavirus disease: evidence of a bidirectional association
    The gastrointestinal (GI) microbiome remains an emerging topic of study and the characterization and impact on human health and disease continue to be an area of great interest. Similarly, the coron [...] Read more.
    Kevin V. Houston ... David A. Johnson
    Published: April 25, 2023 Explor Med. 2023;4:157–165
    DOI: https://doi.org/10.37349/emed.2023.00130
    Times Cited: 0
    Open Access
    Immunomodulation strategies against COVID-19 evidence: key nutrients and dietary approaches
    The novel coronavirus disease-2019 (COVID-19) has created a major public health crisis. Various dietary factors may enhance immunological activity against COVID-19 and serve as a method to combat se [...] Read more.
    Lindsey B. Cundra ... David A. Johnson
    Published: April 25, 2023 Explor Med. 2023;4:189–206
    DOI: https://doi.org/10.37349/emed.2023.00133
    Times Cited: 0
    Open Access
    A budding concept with certain microbiota, anti-proliferative family proteins, and engram theory for the innovative treatment of colon cancer
    Inflammatory bowel disease (IBD) is a multifactorial chronic disease. Patients with IBD have an increased risk of developing colorectal cancer which has become a major health concern. IBD might exer [...] Read more.
    Yuka Ikeda ... Satoru Matsuda
    Published: October 27, 2022 Explor Med. 2022;3:468–478
    DOI: https://doi.org/10.37349/emed.2022.00108
    Open Access
    Feed your microbiome and improve sleep, stress resilience, and cognition
    The brain and gut are connected both physically and biochemically. The gut-brain axis includes the central nervous system, neuroendocrine and neuroimmune systems, the enteric nervous system and vagu [...] Read more.
    Maciej Chichlowski ... Neeraj Pandey
    Published: August 29, 2022 Explor Med. 2022;3:331–344
    DOI: https://doi.org/10.37349/emed.2022.00097
    Open Access
    Does our microbiota eat with or without gluten?
    Giuseppe Merra ... Marco Marchetti
    Published: June 24, 2022 Explor Med. 2022;3:275–279
    DOI: https://doi.org/10.37349/emed.2022.00091
    Times Cited: 0