• Special Issue Topic

    Breast Cancer: Basic and Clinical Advances

    Submission Deadline: December 31, 2023

    Guest Editor

    Dr. Andrea Nicolini E-Mail

    Department of Oncology, Transplantations and New Technologies in Medicine, University of Pisa, Pisa, Italy


    About the Special Issue

    Breast cancer is the most common malignancy worldwide and in females, with a social impact that underlines the relevance of any advances in basic and clinical research. In the last decades, much progress has been made in the comprehension of the molecular mechanisms sustaining tumor growth and diffusion, and certainly a large part of this research has been devoted to breast cancer. As a result of such intense investigation, many mechanisms have been elucidated, and a few targeted therapies through translational research have been introduced into current clinical practice. This is also named as "personalized" or "precision" medicine. This special issue aims to collect any useful scientific contributions in the breast cancer research field , either research or review articles that provide readers with information easy to catch and at the same time in line with the currently evolving studies.

    Keywords: breast cancer, basic research, clinical research, molecular mechanisms, chemotherapy, immunotherapy

    Published Articles

    Open Access
    Mini Review
    Navigating breast health: a comprehensive approach to atypical ductal hyperplasia of the breast management and surveillance
    Atypical ductal hyperplasia (ADH) is a benign lesion of the breast that is associated with an increased risk of invasive breast cancer. This review explores the pathophysiology, risk factors for pro [...] Read more.
    Nadia Islam, Suneela Vegunta
    Published: February 07, 2024 Explor Med. 2024;5:59–64
    DOI: https://doi.org/10.37349/emed.2024.00205
    View:2060
    Download:35
    Times Cited: 0
    Open Access
    Original Article
    Cholesterol de novo biosynthesis: a promising target to overcome the resistance to aromatase inhibitors in postmenopausal patients with estrogen receptor-positive breast cancer
    Aim: Cholesterol is an essential component of cell membranes and serves as a precursor for several bioactive molecules, including steroid hormones and isoprenoids. Generally supplied by the blood [...] Read more.
    Danila Coradini, Federico Ambrogi
    Published: December 29, 2023 Explor Med. 2023;4:1079–1093
    DOI: https://doi.org/10.37349/emed.2023.00196
    View:1667
    Download:24
    Open Access
    Review
    The differential effect of the immune system in breast cancer
    Cancer cure with immunotherapy is an innovative step towards cancer treatment with better survivability, but it is mostly dependent on the response of the patient’s immune system to the immunother [...] Read more.
    Banashree Bondhopadhyay ... Vishakha Kasherwal
    Published: December 29, 2023 Explor Med. 2023;4:1094–1108
    DOI: https://doi.org/10.37349/emed.2023.00197
    View:2093
    Download:39
    Open Access
    Original Article
    Impact of the type of breast cancer on the biodiversity of the vaginal Candida represented by estrogen receptor and its levels
    Aim: Estrogen has an important role in the colonization of Candida through the presence of estrogen receptors (ERs). These ERs are usually used to categorize breast cancer into two types, positiv [...] Read more.
    Ali Abdul Hussein S. AL-Janabi ... Abdul Razzak Kalaf Hassan
    Published: December 06, 2023 Explor Med. 2023;4:878–885
    DOI: https://doi.org/10.37349/emed.2023.00183
    View:1820
    Download:14
    Times Cited: 0