About the Special Issue

In the current era of tissue engineering and regenerative medicine tactics, biomaterials in dentistry are key research areas, and these new advances define the new Frontier in many medical disciplines. Biomaterials play a crucial part in the growth of maxillofacial regenerative therapies, allowing for more complex oral rehabilitation for patients with missing teeth.

Moreover, as evidenced by current scientific literature, the development of new molecular biomarkers constitutes a highly creative and successful diagnostic and therapeutic strategy. The classification of patients based on changes in local/systemic levels of biomolecules may result in the customization of the whole therapy pathway. Oral health professionals—both clinicians and researchers—have accepted the challenge in order to close the gap with other medical disciplines where customized therapy is a well-established reality. For breast cancer and melanoma, genetic typing of the tumor/patient has led to a remarkable improvement in early diagnosis and the identification of treatment targets, altering prognosis and survival significantly.

Despite good observations in animal models and excellent outcomes reported for several existing regenerative procedures and materials in people, there is a lack of rigorous evidence on the extent to which reported clinical benefits represent real bone and periodontal regeneration.

Consequently, the purpose of this Special Issue is to update and consolidate the existing information on the influence of biomaterials in reconstructive bone and defects and atrophies utilizing various types of biomaterials to improve periodontal wound healing or regeneration.

We invite interventional research that aim to further our understanding of the efficacy of biomaterials and biomarkers in dentistry. Review studies, particularly those employing conceptual frameworks, on any of the aforementioned themes are also encouraged.

Keywords: biomaterials, periodontal regeneration, bone regeneration, adjuvants, periodontal disease, peri-implant disease, growth factors, oral surgery, periodontal surgery

Call for Papers