• Subscribe
    • Sign up for updates about the journal.
  • Sign in
  • Register
Exploration of Medicine
  • About
    • About the Journal
    • Editorial Board
    • Editorial Policies
    • Newsletter
    • Contact Us
  • Articles
    • Current Issue
    • Archives
  • Special Issue
    • All Special Issues
    • Guest Editor Guidelines
  • For Authors
    • Author Instructions
    • Editorial Process
    • Article Processing Charge
    • Submit a Manuscript
  • For Reviewers
    • Peer Review Guidelines
    • Reviewer Acknowledgment
    • To Be a Reviewer
  • Focus
  • Home
  • Exploration of Medicine
  • Special Issues
  • Special Issue Topic

    Biomaterials and Biomarkers in Dentistry: Up to Date

    Submission Deadline: December 31, 2023

    Guest Editor

    Prof. Gaetano Isola E-Mail

    Professor, Department of General Surgery and Surgical-Medical Specialties, School of Dentistry, University of Catania, Catania, Italy

    Research Keywords: periodontal disease, periodontal regeneration, biomaterials, salivary diagnostics, oral medicine, biomarkers, oral health, general health, quality of life


    About the Special Issue

    In the current era of tissue engineering and regenerative medicine tactics, biomaterials in dentistry are key research areas, and these new advances define the new Frontier in many medical disciplines. Biomaterials play a crucial part in the growth of maxillofacial regenerative therapies, allowing for more complex oral rehabilitation for patients with missing teeth.

    Moreover, as evidenced by current scientific literature, the development of new molecular biomarkers constitutes a highly creative and successful diagnostic and therapeutic strategy. The classification of patients based on changes in local/systemic levels of biomolecules may result in the customization of the whole therapy pathway. Oral health professionals—both clinicians and researchers—have accepted the challenge in order to close the gap with other medical disciplines where customized therapy is a well-established reality. For breast cancer and melanoma, genetic typing of the tumor/patient has led to a remarkable improvement in early diagnosis and the identification of treatment targets, altering prognosis and survival significantly.

    Despite good observations in animal models and excellent outcomes reported for several existing regenerative procedures and materials in people, there is a lack of rigorous evidence on the extent to which reported clinical benefits represent real bone and periodontal regeneration.

    Consequently, the purpose of this Special Issue is to update and consolidate the existing information on the influence of biomaterials in reconstructive bone and defects and atrophies utilizing various types of biomaterials to improve periodontal wound healing or regeneration.

    We invite interventional research that aim to further our understanding of the efficacy of biomaterials and biomarkers in dentistry. Review studies, particularly those employing conceptual frameworks, on any of the aforementioned themes are also encouraged.

    Keywords: biomaterials, periodontal regeneration, bone regeneration, adjuvants, periodontal disease, peri-implant disease, growth factors, oral surgery, periodontal surgery

    Call for Papers

    Published Articles

    Open Access
    Review
    Impact exerted by scaffolds and biomaterials in periodontal bone and tissue regeneration engineering: new challenges and perspectives for disease treatment
    The periodontium is an appropriate target for regeneration, as it cannot restore its function following disease. Significantly, the periodontium’s limited regenerative capacity could be enhanced through the development of novel  [...] Read more.

    The periodontium is an appropriate target for regeneration, as it cannot restore its function following disease. Significantly, the periodontium’s limited regenerative capacity could be enhanced through the development of novel biomaterials and therapeutic approaches. Notably, the regenerative potential of the periodontium depends not only on its tissue-specific architecture and function but also on its ability to reconstruct distinct tissues and tissue interfaces, implying that the development of tissue engineering techniques can offer new perspectives for the organized reconstruction of soft and hard periodontal tissues. With their biocompatible structure and one-of-a-kind stimulus-responsive property, hydrogels have been utilized as an excellent drug delivery system for the treatment of several oral diseases. Furthermore, bioceramics and three-dimensional (3D) printed scaffolds are also appropriate scaffolding materials for the regeneration of periodontal tissue, bone, and cartilage. This work aims to examine and update material-based, biologically active cues and the deployment of breakthrough bio-fabrication technologies to regenerate the numerous tissues that comprise the periodontium for clinical and scientific applications.

    Simona Santonocito ... Gaetano Isola
    Published: April 26, 2023 Explor Med. 2023;4:215–234
    DOI: https://doi.org/10.37349/emed.2023.00135
    Full Text
    PDF
    View:195
    Download:12
    Times Cited: 0

    The periodontium is an appropriate target for regeneration, as it cannot restore its function following disease. Significantly, the periodontium’s limited regenerative capacity could be enhanced through the development of novel biomaterials and therapeutic approaches. Notably, the regenerative potential of the periodontium depends not only on its tissue-specific architecture and function but also on its ability to reconstruct distinct tissues and tissue interfaces, implying that the development of tissue engineering techniques can offer new perspectives for the organized reconstruction of soft and hard periodontal tissues. With their biocompatible structure and one-of-a-kind stimulus-responsive property, hydrogels have been utilized as an excellent drug delivery system for the treatment of several oral diseases. Furthermore, bioceramics and three-dimensional (3D) printed scaffolds are also appropriate scaffolding materials for the regeneration of periodontal tissue, bone, and cartilage. This work aims to examine and update material-based, biologically active cues and the deployment of breakthrough bio-fabrication technologies to regenerate the numerous tissues that comprise the periodontium for clinical and scientific applications.

    • Submit a Manuscript
    • Aims and Scope
    • Editorial Board
    • Author Instructions
    • Ongoing Special Issues
      The Role of Repetitive DNA Elements in the Development and Progression of Human Disease
      Colon Controlled Microbiome Function: Role, Impact, Structure, Pathogenetic Significance, Therapeutic and Diagnostic Management
      The Role of Gut Microbiota and its Metabolites in Gastrointestinal Diseases
      Recent Advances in Hypertension
      Disease Diagnosis, Molecular Mechanism and Therapeutic Strategies in Kidney Injury and Fibrosis
      Perspectives on Causal Mechanisms, Prevention and Management of Pediatric Obesity and Related Comorbidities
      Beyond Weed: Clinical Applications of Cannabis and Cannabinoids
      The Biological Basis of Substance Use Disorders
      Nanomedicine and Cancer Immunotherapy
      Exploring Aortic Disease
      Cellular Models for In Vitro Modeling of Parkinson’s Disease
      Role of Microbiome in Ocular Diseases
      Advances in Wound Healing
      Determinants of Exceptional Longevity
      Genetic and Epigenetic Control of Autophagy in Human Diseases
      RNA World in Health and Disease
      Lung Fibrosis—Models and Mechanisms
      Exploration of 3D and 4D Printing in the Biomedical and Personalized Medicine Fields: Merits and Challenges
      Biomaterials and Biomarkers in Dentistry: Up to Date
      Gut Microbiota Derived Metabolites and Chronic Inflammatory Diseases
      Vitamin D—Current and the Future
      Emerging Infectious Diseases
      Applications of Radiomics in Precision Medicine
      Functional Biomaterials and Tumor Immunotherapy
      Breast Cancer: Basic and Clinical Advances
      Advances in the Identification and Mechanisms of Action of Luminal Compounds Involved in Inflammatory Bowel Diseases
      Drug Adherence in Hypertension
    • Completed Special Issues
      Exploring NAFLD/NASH
      Digital Biomarkers: The New Frontier for Medicine and Research
      Exploring Type 2 Diabetes Mellitus
      Angiotensins—A Century of Progress
      Exploring Chronic Liver Disease
      Reactive Oxygen Species (ROS) in Pathophysiological Conditions
      Techniques in Repurposing and Targeted Delivery: Bringing a New Life to Shelved Drugs
    • Guest Editor
    • About the Special Issue
    • Call for Papers
    • Published Articles
    • Exploration of Medicine
    • eISSN 2692-3106
    • emjournal@explorationpub.com
    • About the Journal
    • Author Instructions
    • Editorial Board
    • Editorial Policies
    • Editorial Process
    • Follow the Journal
    • JOURNALS
    • Exploration of Medicine
    • Exploration of Targeted Anti-tumor Therapy
    • Exploration of Immunology
    • Exploration of Neuroprotective Therapy
    • Exploration of Digestive Diseases
    • Exploration of Neuroscience
    • Exploration of Musculoskeletal Diseases
    • Exploration of Asthma & Allergy
    • Exploration of Drug Science
    • Exploration of Foods and Foodomics
    • Exploration of BioMat-X
    • Exploration of Digital Health Technologies
    • Exploration of Cardiology
    • Exploration of Endocrine and Metabolic Disease
    • ABOUT
    • Company Information
    • Open Access
    • Editorial Policies
    • Peer Review Policy
    • Contact Us
    • FOLLOW
    • Terms of Service Privacy Cookies
Copyright © 2023 Open Exploration Publishing Inc.