• 64 results in Exploration of Drug Science
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    Original Article
    Hybrid peptides inspired by the RWQWRWQWR sequence inhibit cervical cancer cells growth in vitro
    Aim: The aim of this research was to generate new peptide molecules with cytotoxic activity against cervical cancer that can become effective in mitigating the impact of the disease and preventin [...] Read more.
    Natalia Ardila-Chantré ... Javier Eduardo García-Castañeda
    Published: September 27, 2024 Explor Drug Sci. 2024;2:614–631
    DOI: https://doi.org/10.37349/eds.2024.00064
    This article belongs to the special issue Bioactive Peptides: Pioneering Innovations in Latin American Research
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    Review
    Psoralidin: emerging biological activities of therapeutic benefits and its potential utility in cervical cancer
    Cervical cancer (CaCx) is the fourth most prevalent cancer in women contributing to 341,831 annual deaths globally in 2020. Owing to its high mortality rate, the identification of novel inhibitors p [...] Read more.
    Tanya Tripathi ... Alok Chandra Bharti
    Published: September 24, 2024 Explor Drug Sci. 2024;2:583–613
    DOI: https://doi.org/10.37349/eds.2024.00063
    This article belongs to the special issue Remedial benefits of natural products in inflammation and cancer
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    Review
    Multi-target and natural product-based multi-drug approach for anti-VEGF resistance in glioblastoma
    Glioblastoma (GBM) remains a formidable challenge in neuro-oncology due to its aggressive nature and propensity for therapeutic resistance. Anti-vascular endothelial growth factor (VEGF) therapies,  [...] Read more.
    Sasikumar Jalajakumari Soumya ... Perumana R. Sudhakaran
    Published: September 13, 2024 Explor Drug Sci. 2024;2:567–582
    DOI: https://doi.org/10.37349/eds.2024.00062
    This article belongs to the special issue Remedial benefits of natural products in inflammation and cancer
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    Times Cited: 0
    Open Access
    Original Article
    Clinical utility of combined contrast-enhanced ultrasound and intracavitary contrast-enhanced ultrasound in the percutaneous treatment of pyogenic liver abscess
    Aim: This study aimed to evaluate the utility of the combined use of contrast-enhanced ultrasound (CEUS) and intracavitary CEUS (IC-CEUS) with diluted SonoVue in the management of percutaneous tr [...] Read more.
    Giampiero Francica
    Published: September 13, 2024 Explor Drug Sci. 2024;2:555–566
    DOI: https://doi.org/10.37349/eds.2024.00061
    This article belongs to the special issue Innovative Therapeutics in Hepato-Gastroenterology
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    Review
    Chemo-selective modification of cysteine residue: synthesis and application in the discovery of potential drug candidates
    Chemo-select modification of peptides, targeting a handful of the most reactive proteinogenic amino acids (AAs), is gradually utilized to address the medical needs of peptide drugs and biopharmaceut [...] Read more.
    Yanyan Liao, Xuefeng Jiang
    Published: September 06, 2024 Explor Drug Sci. 2024;2:540–554
    DOI: https://doi.org/10.37349/eds.2024.00060
    This article belongs to the special issue Bioactive Peptides discovery and development
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    Review
    A review of leishmaniasis: current knowledge and future directions of heterocyclic molecules
    Leishmanial diseases, caused by various species of the protozoan parasite Leishmania, continue to pose a significant global health challenge. Medicinal drugs have been at the forefront of combating  [...] Read more.
    Tejaswini Masne ... Deepali Bansode
    Published: September 06, 2024 Explor Drug Sci. 2024;2:508–539
    DOI: https://doi.org/10.37349/eds.2024.00059
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    Review
    A review of the effects of pharmaceutical pollutants on humans and aquatic ecosystem
    The presence of high-quality water is essential not only for human survival but also for the well-being of plants and animals. This research aimed to examine studies investigating the occurrence of  [...] Read more.
    Jaya Vinny Eapen ... Jayesh Antony
    Published: August 28, 2024 Explor Drug Sci. 2024;2:484–507
    DOI: https://doi.org/10.37349/eds.2024.00058
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    Times Cited: 0
    Open Access
    Original Article
    Biological activities of extracts of some plants which utilized in colds
    Aim: In this study, antioxidant activities and antibacterial activities of acetone and chloroform extracts obtained from Rosa canina, Echinacea purpurea, Althaea officinalis and [...] Read more.
    Sinem Aydin
    Published: August 22, 2024 Explor Drug Sci. 2024;2:473–483
    DOI: https://doi.org/10.37349/eds.2024.00057
    This article belongs to the special issue Discovery and development of new antibacterial compounds
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    Review
    Decoding vascular aging: implications for atherosclerosis progression and clinical intervention
    Age-related pathologies, particularly cardiovascular disorders, pose a significant global health concern. The World Health Organization (WHO) predicts an increase in advanced mortality by 2030 unles [...] Read more.
    Silumbwe Ceaser Wankumbu ... Ming Xu
    Published: August 02, 2024 Explor Drug Sci. 2024;2:449–472
    DOI: https://doi.org/10.37349/eds.2024.00056
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    Review
    Metformin in COVID-19: a magical role beyond the hyperglycemia
    Coronavirus disease-2019 (COVID-19) has emerged as an aggressive viral infection in the last few years. Initially reported in the Wuhan area of the People’s Republic of China, it soon emerged acro [...] Read more.
    Gaurav Kumar Chaubey ... Manoj Raje
    Published: July 31, 2024 Explor Drug Sci. 2024;2:428–448
    DOI: https://doi.org/10.37349/eds.2024.00055
    View:633
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