Exploration of Drug Science

Open Access Original Article

Prophylactic metoclopramide for preventing opioid-induced nausea and vomiting in cancer pain: a retrospective cohort study

Xianglian Ma ... Jiuda Zhao

Published: February 02, 2026 Explor Drug Sci. 2026;4:1008148

DOI: https://doi.org/10.37349/eds.2026.1008148

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Open Access Review

Vinyl sulfones: selective and tunable covalent warheads against challenging enzyme targets

Ronald E. Viola

Published: February 01, 2026 Explor Drug Sci. 2026;4:1008147

DOI: https://doi.org/10.37349/eds.2026.1008147

This article belongs to the special issue The Rise of Targeted Covalent Inhibitors in Drug Discovery

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Open Access Case Report

A case series of CBT-inspired behavioral and medical interventions for uncontrolled type 2 diabetes

Ahmed Nouri, Bassam Abu Madi

Published: February 01, 2026 Explor Drug Sci. 2026;4:1008146

DOI: https://doi.org/10.37349/eds.2026.1008146

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175 15 0

Open Access Original Article

Small molecule and fragment-based phenotypic screening for novel building blocks with antimycobacterial activity

Monika I. Konaklieva ... Balbina J. Plotkin

Published: February 01, 2026 Explor Drug Sci. 2026;4:1008145

DOI: https://doi.org/10.37349/eds.2026.1008145

This article belongs to the special issue Discovery and development of new antibacterial compounds

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Open Access Systematic Review

Harnessing nanomaterials to overcome antimicrobial resistance in Gram-positive bacteria: a systematic review

Olalekan John Okesanya ... Don Eliseo Lucero-Prisno III

Published: January 28, 2026 Explor Drug Sci. 2026;4:1008144

DOI: https://doi.org/10.37349/eds.2026.1008144

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369 21 0

Open Access Systematic Review

Janus-faced role of anti-infective drugs: a revisit through the lens of vascular ageing

Ceaser Wankumbu Silumbwe ... Kebby Mazyamuna

Published: January 14, 2026 Explor Drug Sci. 2026;4:1008143

DOI: https://doi.org/10.37349/eds.2026.1008143

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Open Access Correction

Correction: High-risk neuroblastoma stage 4 (NBS4): multi-target inhibitors for c-Src kinases (Csk) and retinoic acid (RA) signalling pathways

Amgad Gerges, Una Canning

Published: January 09, 2026 Explor Drug Sci. 2026;4:1008142

DOI: https://doi.org/10.37349/eds.2026.1008142

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171 12 0

Open Access Review

Innovative immunotherapies for prostate cancer: understanding the synergies between checkpoint inhibition, CAR T-cell therapy, and next-generation therapeutic modalities

Daniel Kofi Nyame ... Xiaohui Zhou

Published: January 09, 2026 Explor Drug Sci. 2026;4:1008141

DOI: https://doi.org/10.37349/eds.2026.1008141

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Open Access Original Article

Multiscale computational profiling of a promising carbapenemase inhibitor: from binding dynamics to quantum reactivity

Ayuba Olanrewaju Mustapha ... Yusuf Oloruntoyin Ayipo

Published: January 09, 2026 Explor Drug Sci. 2026;4:1008140

DOI: https://doi.org/10.37349/eds.2026.1008140

This article belongs to the special issue Discovery and development of new antibacterial compounds

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377 13 0

Open Access Systematic Review

Targeted therapeutic management of diabetes using phytoconstituents: molecular mechanisms, evidence map (2015–2025), and translational outlook

Chizurum Philip Ikegbuna ... Mmesoma Ruth Ikegbuna

Published: January 07, 2026 Explor Drug Sci. 2026;4:1008139

DOI: https://doi.org/10.37349/eds.2026.1008139

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Open Access Original Article

Novel antimicrobial efficacy on inert surfaces of chlorhexidine-silver nanoparticle veterinary formulation

Daniel Buldain ... Laura Marchetti

Published: January 05, 2026 Explor Drug Sci. 2026;4:1008138

DOI: https://doi.org/10.37349/eds.2026.1008138

This article belongs to the special issue Discovery and development of new antibacterial compounds

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