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Exploration of Medicine
  • " >
    Special Issue Topic

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    Submission Deadline:

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    January 01, 1970

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    Guest Editor

    About the Special Issue

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    Published Articles

    Open Access
    Review
    The progression of sepsis from physiologic systemic inflammatory response to immune dysregulation due to life-threatening infections
    Sepsis was defined in 1991 by the systemic inflammatory response syndrome (SIRS) criteria which consisted mostly of physiologic responses to infection or inflammation (fever, tachycardia, tachypnea, [...] Read more.
    Nicholas Daering, Majdi N. Al-Hasan
    Published: October 25, 2022 Explor Immunol. 2022;2:665–676
    DOI: https://doi.org/10.37349/ei.2022.00075
    View:1225
    Download:33
    Times Cited: 0
    Open Access
    Review
    Understanding sepsis-induced immunosuppression and organ dysfunctions: from immunosuppression to immunotherapy
    Sepsis is a life-threatening condition caused by dysregulated host immune response to infection, leading to persistent inflammation followed by immunosuppression. Sepsis represents a substantial glo [...] Read more.
    Dablu Lal Gupta ... D. N. Rao
    Published: August 29, 2022 Explor Immunol. 2022;2:589–603
    DOI: https://doi.org/10.37349/ei.2022.00070
    View:1435
    Download:48
    Times Cited: 0
    Open Access
    Review
    Small molecules targeting endolysosomal acidification and signaling in sepsis and severe SARS-CoV-2 infection/COVID-19
    Sepsis and severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection, and its severe form coronavirus disease 2019 (COVID-19), represent the major medical challenges of the modern era.  [...] Read more.
    Markus Blaess ... Hans-Peter Deigner
    Published: August 11, 2022 Explor Immunol. 2022;2:484–509
    DOI: https://doi.org/10.37349/ei.2022.00063
    View:1566
    Download:36
    Open Access
    Review
    In COVID-19, antigen size lower or larger than 70 kDa modulates the sepsis and memory B cells
    This review pretends to shed light on the immune processes occurring in the coronavirus disease 2019 (COVID-19) from a perspective based on the antigens size, lower or larger than 70 kDa. This cutof [...] Read more.
    Francisco Javier Martín Oncina
    Published: July 17, 2022 Explor Immunol. 2022;2:442–453
    DOI: https://doi.org/10.37349/ei.2022.00061
    View:1505
    Download:33
    Times Cited: 0
    Open Access
    Review
    Janus face of sepsis: a viewpoint
    Treatment of sepsis currently relies on eliminating the causal pathogen and supportive care, whereas almost no approaches to interfere with the defining event of a “dysregulated host response” are available. This review points [...] Read more.
    Michael Bauer, Reinhard Wetzker
    Published: May 24, 2022 Explor Immunol. 2022;2:293–302
    DOI: https://doi.org/10.37349/ei.2022.00051
    View:1322
    Download:30
    Times Cited: 0
    Open Access
    Original Article
    Thymosin alpha 1 therapy alleviates organ dysfunction of sepsis patients: a retrospective cohort study
    Aim: Thymosin alpha 1 (Tα1) is a promising treatment for the improvement of sepsis patients. Until now, its function in reducing acute organ damage of sepsis patients is still unclear. The aim of this study was to determine wheth [...] Read more.
    Fei Pei ... on behalf of the China Critical Care Immunotherapy Research Group
    Published: April 22, 2022 Explor Immunol. 2022;2:200–210
    DOI: https://doi.org/10.37349/ei.2022.00045
    View:1861
    Download:58
    • Guest Editor
    • About the Special Issue
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    • Published Articles