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  • Special Issue Topic

    Advances in the Identification and Mechanisms of Action of Luminal Compounds Involved in Inflammatory Bowel Diseases

    Submission Deadline: February 29, 2024

    Guest Editor

    Dr. Francois Blachier E-Mail

    Research Director, National Institute for Agriculture, Alimentation, and Environment (INRAe), France


    About the Special Issue

    Chronic inflammation of the intestinal mucosa is considered to result from inappropriate mucosal immune responses against components present in the luminal fluid in genetically predisposed individuals, with alternating relapse and remission episodes. The aim of this special issue is to present recent advances in the field of the identification of luminal compounds (bacterial toxins, bacterial metabolites, components of the bacterial cells) that appear implicated in the development of inflammatory bowel diseases (ulcerative colitis, Crohn’s disease, and irritable bowel syndrome). Also, advances on the presumed mechanisms of action that link modifications of the composition of the luminal environment to signs of mucosal inflammation in different situations will be developed.

    This special issue of Exploration of Medicine will bring together data from both experimental and clinical works in the form of Original Article and Review papers.

    Keywords: Inflammatory bowel diseases, luminal environment, bacterial toxins, bacterial metabolites, bacterial components

    Published Articles

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    • Ongoing Special Issues
      The Role of Repetitive DNA Elements in the Development and Progression of Human Disease
      Colon Controlled Microbiome Function: Role, Impact, Structure, Pathogenetic Significance, Therapeutic and Diagnostic Management
      The Role of Gut Microbiota and its Metabolites in Gastrointestinal Diseases
      Recent Advances in Hypertension
      Disease Diagnosis, Molecular Mechanism and Therapeutic Strategies in Kidney Injury and Fibrosis
      Perspectives on Causal Mechanisms, Prevention and Management of Pediatric Obesity and Related Comorbidities
      Beyond Weed: Clinical Applications of Cannabis and Cannabinoids
      The Biological Basis of Substance Use Disorders
      Nanomedicine and Cancer Immunotherapy
      Exploring Aortic Disease
      Cellular Models for In Vitro Modeling of Parkinson’s Disease
      Role of Microbiome in Ocular Diseases
      Advances in Wound Healing
      Determinants of Exceptional Longevity
      Genetic and Epigenetic Control of Autophagy in Human Diseases
      RNA World in Health and Disease
      Lung Fibrosis—Models and Mechanisms
      Exploration of 3D and 4D Printing in the Biomedical and Personalized Medicine Fields: Merits and Challenges
      Biomaterials and Biomarkers in Dentistry: Up to Date
      Gut Microbiota Derived Metabolites and Chronic Inflammatory Diseases
      Vitamin D—Current and the Future
      Emerging Infectious Diseases
      Applications of Radiomics in Precision Medicine
      Functional Biomaterials and Tumor Immunotherapy
      Breast Cancer: Basic and Clinical Advances
      Existing, New and Potential Pharmacological Agents from Mushrooms
      Advances in the Identification and Mechanisms of Action of Luminal Compounds Involved in Inflammatory Bowel Diseases
      Spotlight on Cervical Cancer: Prevention, Early-Diagnosis, and Treatments
      Drug Adherence in Hypertension
      Standard and Emerging Treatments for Hepatocellular Carcinoma
    • Completed Special Issues
      Exploring NAFLD/NASH
      Digital Biomarkers: The New Frontier for Medicine and Research
      Exploring Type 2 Diabetes Mellitus
      Angiotensins—A Century of Progress
      Exploring Chronic Liver Disease
      Reactive Oxygen Species (ROS) in Pathophysiological Conditions
      Techniques in Repurposing and Targeted Delivery: Bringing a New Life to Shelved Drugs
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