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  • 89 results in Exploration of Neuroscience
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    Open Access
    Case Report
    Isolated lymphoma of the choroid plexus: a case report
    The choroid plexus, pivotal for cerebrospinal fluid (CSF) regulation and blood-CSF barrier function, becomes a focal point for primary central nervous system lymphoma (PCNSL). This article delves in [...] Read more.
    Ali Msheik ... Zeinab Al Mokdad
    Published: May 20, 2025 Explor Neurosci. 2025;4:100689
    DOI: https://doi.org/10.37349/en.2025.100689
    View:17
    Download:3
    Times Cited: 0
    Open Access
    Review
    Association between CD36 and ischemic stroke: consequential or coincidental?
    CD36 is a transmembrane protein that plays a role in various biological processes, including oxidized low-density lipoprotein and fatty acid uptake as well as regulatory control for inflammation sig [...] Read more.
    Ana-Maria Dobri-Nicoară ... Cristiana Tanase
    Published: May 11, 2025 Explor Neurosci. 2025;4:100688
    DOI: https://doi.org/10.37349/en.2025.100688
    This article belongs to the special issue Cerebral Ischemia, Genetics, Comorbidities, Risk Factors and New Therapeutic Options for Neurorestoration
    View:129
    Download:6
    Times Cited: 0
    Open Access
    Original Article
    Intracerebral hemorrhage (ICH) in easternmost Finland 2021–2023
    Aim: To report the incidence, characteristics, and prognosis of spontaneous intracerebral hemorrhage (ICH) in North Karelia Central Hospital Primary Stroke Center (PSC). Methods: All patients admitted with ICH to North Karelia Cen [...] Read more.
    Jussi O.T. Sipilä ... Anne-Mari Kantanen
    Published: May 08, 2025 Explor Neurosci. 2025;4:100687
    DOI: https://doi.org/10.37349/en.2025.100687
    View:181
    Download:6
    Times Cited: 0
    Open Access
    Review
    Neuropathic pain: proposal of a mechanism-based treatment
    Neuropathic pain, defined by the International Association for the Study of Pain as “pain caused by a lesion or disease of the somatosensory system”, has an estimated prevalence of 7–9.2% in t [...] Read more.
    Laura Demartini, Cesare Bonezzi
    Published: April 27, 2025 Explor Neurosci. 2025;4:100686
    DOI: https://doi.org/10.37349/en.2025.100686
    This article belongs to the special issue Neuropathic Pain
    View:311
    Download:12
    Times Cited: 0
    Open Access
    Original Article
    Application of TELC model to better elucidate neural stimulation by touch
    Aim: This study is to better understand how the transient ion transport activity of touch receptors could change the graded potential to stimulate an action potential firing. Methods: The l [...] Read more.
    James Weifu Lee
    Published: April 26, 2025 Explor Neurosci. 2025;4:100685
    DOI: https://doi.org/10.37349/en.2025.100685
    View:214
    Download:8
    Times Cited: 0
    Open Access
    Original Article
    Correlation between self-perceived cognitive problems and objective cognitive impairment in non-CNS cancer patients in a resource-constrained health setting in South Africa
    Aim: Cognitive complaints are frequent among cancer patients. These issues can significantly affect the patient’s quality of life and are linked to a higher risk of developing dementia. However [...] Read more.
    Antonio G. Lentoor, Tiro B. Motsamai
    Published: April 16, 2025 Explor Neurosci. 2025;4:100684
    DOI: https://doi.org/10.37349/en.2025.100684
    View:308
    Download:5
    Times Cited: 0
    Open Access
    Perspective
    Moving forward: may some of “functional” gut disorders be reclassified as enteric neuro-gliopathies?
    “Functional” gut disorders are clinical conditions frequently encountered in clinical practice, often characterized by abnormalities of the intestinal sensory and motor functions. Although tradi [...] Read more.
    Gabrio Bassotti
    Published: April 11, 2025 Explor Neurosci. 2025;4:100683
    DOI: https://doi.org/10.37349/en.2025.100683
    This article belongs to the special issue Enteric Neuro-Gliopathies: Ready for Prime Time?
    View:296
    Download:13
    Times Cited: 0
    Open Access
    Mini Review
    Mechanisms of action of formononetin, an extract from Astragalus membranaceus medicinal plant, in ameliorating Alzheimer’s disease
    Alzheimer’s disease (AD), the term “dementia”, describes a specific neuropathology together with the development and progression of age-related cognitive and functional loss. Formononetin is n [...] Read more.
    Manpreet Kaur ... Anish Singh
    Published: April 02, 2025 Explor Neurosci. 2025;4:100682
    DOI: https://doi.org/10.37349/en.2025.100682
    This article belongs to the special issue Medicinal Plants and Bioactive Phytochemicals in Neuroprotection
    View:581
    Download:16
    Times Cited: 0
    Open Access
    Review
    Translocator protein (TSPO) in glioma: implications for diagnosis, disease progression monitoring, and targeted therapies
    Glioma is a highly aggressive brain cancer associated with significant mortality. Despite advances in diagnostic and therapeutic strategies, the prognosis for glioma patients remains poor due to lim [...] Read more.
    Julius Mulumba ... Yong Yang
    Published: April 01, 2025 Explor Neurosci. 2025;4:100681
    DOI: https://doi.org/10.37349/en.2025.100681
    This article belongs to the special issue Current Approaches to Malignant Tumors of the Nervous System
    View:535
    Download:12
    Times Cited: 0
    Open Access
    Review
    Sigma-1 receptor as an emerging target for painful diabetic neuropathy—a review
    Neuropathic pain (NP) is a significant global health challenge, affecting an estimated 7–10% of the population. Painful diabetic neuropathy (PDN), a severe complication of diabetes, impacts approx [...] Read more.
    Youyi Peng ... Shan Chen
    Published: April 01, 2025 Explor Neurosci. 2025;4:100680
    DOI: https://doi.org/10.37349/en.2025.100680
    This article belongs to the special issue Neuropathic Pain
    View:565
    Download:24
    Times Cited: 0
    Open Access
    Editorial
    Celebrating the legacy of Russel J. Reiter: a pioneer in melatonin research
    Dirk M. Hermann, Ertugrul Kilic
    Published: March 24, 2025 Explor Neurosci. 2025;4:100679
    DOI: https://doi.org/10.37349/en.2025.100679
    This article belongs to the special issue Identification of Therapeutic Targets in the Pathogenesis of Neurological Diseases
    View:690
    Download:25
    Times Cited: 0
    Open Access
    Review
    Melatonin regulation of phase separation in Neuro-PASC: out-maneuvering Janus-faced amyloids
    The SAR-CoV-2 virus has evolved to co-exist with human hosts, albeit at a substantial energetic cost resulting in post-infection neurological manifestations [Neuro-post-acute sequelae of SARS-CoV-2  [...] Read more.
    Doris Loh, Russel J. Reiter
    Published: March 24, 2025 Explor Neurosci. 2025;4:100678
    DOI: https://doi.org/10.37349/en.2025.100678
    This article belongs to the special issue Identification of Therapeutic Targets in the Pathogenesis of Neurological Diseases
    View:4756
    Download:85
    Open Access
    Original Article
    Raw resting-state electroencephalogram biomarker emerges as an indicator of Alzheimer’s disease over a two-year period
    Aim: Alzheimer’s disease (AD) is associated with several electrophysiological biomarkers. These biomarkers are associated with global decline in cognition and a diagnosis of AD. However, a spec [...] Read more.
    Ezra C. Holston
    Published: March 24, 2025 Explor Neurosci. 2025;4:100677
    DOI: https://doi.org/10.37349/en.2025.100677
    This article belongs to the special issue Alzheimer's Disease
    View:391
    Download:8
    Times Cited: 0
    Open Access
    Review
    Mechanisms of astrocytic and microglial purinergic signaling in homeostatic regulation and implications for neurological disease
    Purinergic signaling, mediated by ATP and adenosine receptors, plays a crucial role in cellular communication and homeostasis within the central nervous system (CNS), particularly by regulating syna [...] Read more.
    Moawiah M Naffaa
    Published: March 11, 2025 Explor Neurosci. 2025;4:100676
    DOI: https://doi.org/10.37349/en.2025.100676
    This article belongs to the special issue Purinergic Signaling in Neuroinflammation and Pain
    View:1119
    Download:18
    Times Cited: 0
    Open Access
    Review
    The role of neuroimaging in Alzheimer’s disease: implications for the diagnosis, monitoring disease progression, and treatment
    Alzheimer’s disease (AD) is a neurodegenerative disorder that affects millions of people worldwide. It presents a significant challenge in terms of accurate diagnosis, disease progression monitori [...] Read more.
    Julius Mulumba ... Yong Yang
    Published: February 25, 2025 Explor Neurosci. 2025;4:100675
    DOI: https://doi.org/10.37349/en.2025.100675
    This article belongs to the special issue Alzheimer's Disease
    View:2407
    Download:43
    Times Cited: 0
    Open Access
    Review
    Neurostimulation devices to treat Alzheimer’s disease
    The use of neurostimulation devices for the treatment of Alzheimer’s disease (AD) is a growing field. In this review, we examine the mechanism of action and therapeutic indications of these neuros [...] Read more.
    Felipe P. Perez ... Maher Rizkalla
    Published: February 25, 2025 Explor Neurosci. 2025;4:100674
    DOI: https://doi.org/10.37349/en.2025.100674
    This article belongs to the special issue Alzheimer's Disease
    View:1233
    Download:30
    Open Access
    Review
    Neuroprotective insights into epigallocatechin gallate (EGCG) for neurodegenerative disorders
    Neurodegenerative disorders, including Alzheimer’s, Parkinson’s, Huntington’s, and amyotrophic lateral sclerosis, are among the most significant health concerns worldwide, characterized by neu [...] Read more.
    Neha Kamboj ... Rahul Kumar
    Published: February 24, 2025 Explor Neurosci. 2025;4:100673
    DOI: https://doi.org/10.37349/en.2025.100673
    This article belongs to the special issue Medicinal Plants and Bioactive Phytochemicals in Neuroprotection
    View:2832
    Download:29
    Times Cited: 0
    Open Access
    Review
    Anti-amyloid β hydrophobic peptides in Alzheimer’s disease: biomarkers and therapeutic potential
    Intracellular amyloid β oligomers (AβOs) have been linked to Alzheimer’s disease (AD) pathogenesis and to the neuronal damage in this neurodegenerative disease. Calmodulin, which binds AβO with [...] Read more.
    Carlos Gutierrez-Merino
    Published: February 24, 2025 Explor Neurosci. 2025;4:100672
    DOI: https://doi.org/10.37349/en.2025.100672
    This article belongs to the special issue Alzheimer's Disease
    View:562
    Download:14
    Times Cited: 0
    Open Access
    Review
    Intracranial artery dolichoectasia: What should the neurologist know?
    Intracranial artery dolichoectasia (IADE) is a vascular anomaly characterized by dilation and/or tortuosity of one or more intracranial arteries. While many cases are incidental findings on imaging, [...] Read more.
    Lorena Dellagnesi Depieri ... Lorena Souza Viana
    Published: January 26, 2025 Explor Neurosci. 2025;4:100671
    DOI: https://doi.org/10.37349/en.2025.100671
    This article belongs to the special issue Cerebral Ischemia, Genetics, Comorbidities, Risk Factors and New Therapeutic Options for Neurorestoration
    View:895
    Download:17
    Times Cited: 0
    Open Access
    Editorial
    Epilepsy
    Epilepsy, a complex and widespread neurological disorder, has evolved in its understanding from ancient misconceptions to modern scientific advancements. This special issue highlights pivotal resear [...] Read more.
    Jinwei Zhang
    Published: January 15, 2025 Explor Neurosci. 2025;4:100670
    DOI: https://doi.org/10.37349/en.2025.100670
    This article belongs to the special issue Epilepsy
    View:775
    Download:43
    Times Cited: 0