• 14 results in Exploration of Neuroscience
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    Review
    Inflammatory responses involved in post-cardiac arrest brain injury: mechanisms, regulation, and therapeutic potential
    Neuroinflammation plays a key role in the pathogenesis of post-cardiac arrest (CA) brain injury. Innate immune cells sense a variety of danger signals through pattern-recognition receptors and evoke [...] Read more.
    Yuzhen Zhang ... Kaibin Huang
    Published: April 26, 2023 Explor Neurosci. 2023;2:82–97
    DOI: https://doi.org/10.37349/en.2023.00014
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    Times Cited: 0
    Open Access
    Review
    Metabolic correction of neurodegenerative pathologies: the role of macronutrients and timing
    Despite decades of intensive research, effective treatment and prevention strategies for neurodegenerative diseases (NDDs) remain elusive. This review focuses on Alzheimer’s and Parkinson’s dise [...] Read more.
    Yuri Zilberter, Tanya Zilberter
    Published: April 21, 2023 Explor Neurosci. 2023;2:67–81
    DOI: https://doi.org/10.37349/en.2023.00013
    View:139
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    Times Cited: 0
    Open Access
    Original Article
    The effect of the tumour necrosis factor-alpha-inhibitor etanercept on microglial activation patients with mild cognitive impairment—a PET study
    Aim: Microglial activation is increasingly recognised as a factor in the progression of Alzheimer’s disease (AD) and may be modified by systemic inflammatory signals including serum tumour necrosis factor (TNF)-α. The aim was t [...] Read more.
    Alexander Gerhard ... Clive Holmes
    Published: March 26, 2023 Explor Neurosci. 2023;2:52–66
    DOI: https://doi.org/10.37349/en.2023.00012
    View:196
    Download:17
    Times Cited: 0
    Open Access
    Editorial
    Treatment concept successfully translated into human patients
    Dirk M. Hermann
    Published: February 28, 2023 Explor Neurosci. 2023;2:48–51
    DOI: https://doi.org/10.37349/en.2023.00011
    View:187
    Download:15
    Times Cited: 0
    Open Access
    Systematic Review
    Genetic plasma biomarkers associated with ischemic stroke
    Aim: Stroke is one of the leading causes of death and disability worldwide. Plasma biomarkers have long been used to evaluate physiological or pathological processes and to make predictions about [...] Read more.
    Mihai Andrei Ruscu ... Aurel Popa-Wagner
    Published: February 26, 2023 Explor Neurosci. 2023;2:27–47
    DOI: https://doi.org/10.37349/en.2023.00010
    This article belongs to the special issue Cerebral Ischemia, Genetics, Comorbidities, Risk Factors and New Therapeutic Options for Neurorestoration
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    Times Cited: 0
    Open Access
    Review
    Update for astrocytomas: medical and surgical management considerations
    Astrocytomas include a wide range of tumors with unique mutations and varying grades of malignancy. These tumors all originate from the astrocyte, a star-shaped glial cell that plays a major role in [...] Read more.
    Matthew Willman ... Brandon Lucke-Wold
    Published: February 23, 2023 Explor Neurosci. 2023;2:1–26
    DOI: https://doi.org/10.37349/en.2023.00009
    This article belongs to the special issue Emerging Trends in Endovascular Management
    View:302
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    Open Access
    Review
    Cellular and molecular mechanisms of stress-induced memory impairment
    Exposure to stressful conditions plays a critical role in brain processes, including neural plasticity, synaptic transmission, and cognitive functions. Since memory-related brain regions, the hippocampus (Hip), the amygdala, and t [...] Read more.
    Ameneh Rezayof ... Shiva Hashemizadeh
    Published: December 30, 2022 Explor Neurosci. 2022;1:100–119
    DOI: https://doi.org/10.37349/en.2022.00008
    This article belongs to the special issue Neuroinflammation in the Ageing and the Injured Brain
    View:288
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    Times Cited: 0
    Open Access
    Review
    Updates in mechanical thrombectomy
    Stroke is a leading cause of morbidity and mortality. The advent of mechanical thrombectomy has largely improved patient outcomes. This article reviews the features and outcomes associated with aspi [...] Read more.
    Kevin Pierre ... Brandon Lucke-Wold
    Published: December 30, 2022 Explor Neurosci. 2022;1:83–99
    DOI: https://doi.org/10.37349/en.2022.00007
    This article belongs to the special issue Emerging Trends in Endovascular Management
    View:382
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    Times Cited: 0
    Open Access
    Perspective
    Should we rethink neurodegeneration?
    The therapy of many neurological disorders has advanced markedly during recent decades. Not so for neurodegenerative disorders. Early detection, deep individual genotyping and phenotyping, and perso [...] Read more.
    Jussi O. T. Sipilä
    Published: December 26, 2022 Explor Neurosci. 2022;1:75–82
    DOI: https://doi.org/10.37349/en.2022.00006
    View:262
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    Times Cited: 0
    Open Access
    Review
    Neuroprotective and neurorestorative actions of mesenchymal stromal cell-derived small extracellular vesicles in the ischemic brain
    Ischemic stroke is a highly prevalent condition that frequently results in life-long disability and death. Considerable efforts have been made to establish treatments that prevent secondary ischemic [...] Read more.
    Chen Wang ... Dirk M. Hermann
    Published: October 09, 2022 Explor Neurosci. 2022;1:61–74
    DOI: https://doi.org/10.37349/en.2022.00005
    This article belongs to the special issue Extracellular Vesicles as Cell-based Therapeutics
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    Times Cited: 0
    Open Access
    Perspective
    Recent developments and future perspectives of neuropathology
    This brief statement describes some recent achievements of neuropathological research, with the focus on Alzheimer’s and other age-related diseases, neurodegenerative disorders (tauopathies, synucleinopathies), multimorbidity of [...] Read more.
    Kurt A. Jellinger
    Published: September 30, 2022 Explor Neurosci. 2022;1:54–60
    DOI: https://doi.org/10.37349/en.2022.00004
    Open Access
    Review
    Neuregulins: subcellular localization, signaling pathways and their relationship with neuroplasticity and neurological diseases
    Neuregulins (NRGs) and their cognate ErbB receptors (ErbB2–ErbB4) constitute a vast group of proteins encoded by six different genes (NRG16) and many isoforms with critical  [...] Read more.
    Marines Longart ... Juan Carlos Martínez
    Published: September 29, 2022 Explor Neurosci. 2022;1:31–53
    DOI: https://doi.org/10.37349/en.2022.00003
    Open Access
    Review
    Impact of circadian clock dysfunction on human health
    All living organisms exhibit circadian rhythms. Humans show circadian rhythm of the different physiological functions such as sleep-wake cycle, core body temperature, feeding behavior, metabolic act [...] Read more.
    Saptadip Samanta, Sk Asif Ali
    Published: September 29, 2022 Explor Neurosci. 2022;1:4–30
    DOI: https://doi.org/10.37349/en.2022.00002
    This article belongs to the special issue Circadian Rhythm and Melatonin
    View:801
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    Times Cited: 0
    Open Access
    Editorial
    Cutting edges in neuroscience to exceed borders
    Dirk M. Hermann
    Published: September 01, 2022 Explor Neurosci. 2022;1:1–3
    DOI: https://doi.org/10.37349/en.2022.00001