• 15 results in Exploration of Endocrine and Metabolic Diseases
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    Original Article
    Testosterone undecanoate is associated with improved ageing male symptoms score in men with type 2 diabetes and adult-onset testosterone deficiency: re-analyzed results from a randomised controlled trial
    Aim: To evaluate changes in quality of life via the ageing male symptom scale (AMSS) and somatic, psychological, and sexual sub-scales following testosterone undecanoate (TU) or placebo (P) treat [...] Read more.
    Pravinath Ramachandran ... Geoffrey Hackett
    Published: August 13, 2024 Explor Endocr Metab Dis. 2024;1:177–190
    DOI: https://doi.org/10.37349/eemd.2024.00015
    This article belongs to the special issue The Fountain of Youth: Decoding the Hormonal Regulation of Aging
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    Open Access
    Original Article
    Glycemic trends, app engagement and achievement of gestational diabetes guideline targets using a diabetes app and Bluetooth® connected blood glucose meters
    Aim: Current diabetes guidelines recommend people with gestational diabetes mellitus (PwGDM) use primarily blood glucose meters (BGM) for diabetes management. We evaluated glycemic trends and gui [...] Read more.
    Mike Grady ... Elizabeth Holt
    Published: July 24, 2024 Explor Endocr Metab Dis. 2024;1:167–176
    DOI: https://doi.org/10.37349/eemd.2024.00014
    This article belongs to the special issue The Impact of Digitalization To Improve Nutrition and Self-Management in Patients With Diabetes
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    Commentary
    The 2024 American Diabetes Association guidelines on Standards of Medical Care in Diabetes: key takeaways for laboratory
    The escalating prevalence of diabetes poses a significant health concern. Uncontrolled diabetes leads to a multitude of complications. A comprehensive management plan and continual adaptation of gui [...] Read more.
    Dipti Tiwari, Tar Choon Aw
    Published: July 23, 2024 Explor Endocr Metab Dis. 2024;1:158–166
    DOI: https://doi.org/10.37349/eemd.2024.00013
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    Review
    Hypothetical involvement of stress hormones-induced reprograming of adult stem/progenitor cells in tumorigenesis
    Stress is a state of threatened or perceived as threatened homeostasis that can be induced by various external and internal stimuli such as psychosocial factors, inflammatory or injurious conditions [...] Read more.
    Waldemar Kanczkowski ... George P. Chrousos
    Published: July 15, 2024 Explor Endocr Metab Dis. 2024;1:122–157
    DOI: https://doi.org/10.37349/eemd.2024.00012
    This article belongs to the special issue The HPA Axis in Health and Disease
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    Review
    Genome editing in the adrenal gland: a novel strategy for treating congenital adrenal hyperplasia
    Congenital adrenal hyperplasia due to 21-hydroxylase deficiency leads to high morbidity and mortality, despite the availability of life-saving corticosteroid replacement therapy. Gene therapy repres [...] Read more.
    Eva B. van Dijk ... Lara E. Graves
    Published: July 09, 2024 Explor Endocr Metab Dis. 2024;1:101–121
    DOI: https://doi.org/10.37349/eemd.2024.00011
    This article belongs to the special issue The HPA Axis in Health and Disease
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    Open Access
    Review
    Adult-onset testosterone deficiency: the usefulness of hormone replacement in reducing mortality in men with this common age-related condition
    Adult-onset testosterone deficiency (TD) in men is diagnosed by the finding of low serum testosterone levels and recognised, associated symptoms. The condition has high prevalence in men over 50 yea [...] Read more.
    Amar Mann ... Sudarshan Ramachandran
    Published: June 28, 2024 Explor Endocr Metab Dis. 2024;1:83–100
    DOI: https://doi.org/10.37349/eemd.2024.00010
    This article belongs to the special issue The Fountain of Youth: Decoding the Hormonal Regulation of Aging
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    Times Cited: 0
    Open Access
    Case Report
    Hypoparathyroidism, deafness and renal dysplasia syndrome with bilateral cataract and bicornuate uterus caused by a de novo GATA3 mutation
    Hypoparathyroidism, deafness and renal dysplasia (HDR) syndrome is a rare genetic disorder caused by haploinsufficiency of the GATA3 gene. A very limited number of cases have been reported in the li [...] Read more.
    Rajesh Chetiwal ... Priyank Rastogi
    Published: May 27, 2024 Explor Endocr Metab Dis. 2024;1:77–82
    DOI: https://doi.org/10.37349/eemd.2024.00009
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    Original Article
    Four hepatic steatosis indices in predicting quantitative computed tomography-based metabolic dysfunction-associated fatty liver disease
    Aim: To evaluate the prediction ability for quantitative computed tomography (QCT)-based metabolic dysfunction-associated fatty liver disease (MAFLD) of four widely known hepatic steatosis algori [...] Read more.
    Bingwu Xu ... Yong Zhang
    Published: May 23, 2024 Explor Endocr Metab Dis. 2024;1:62–76
    DOI: https://doi.org/10.37349/eemd.2024.00008
    This article belongs to the special issue Regulators of Glucose Homeostasis, Lipid Metabolism and Energy Balance
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    Perspective
    Diabetes and cancer: two epidemic diseases requiring an opposite therapeutic approach to target cells
    Diabetes and cancer are two chronic metabolic diseases with ever-increasing incidence rates worldwide. These disorders can often occur together, as diabetes presents an important risk factor for can [...] Read more.
    Katrin Sak
    Published: May 23, 2024 Explor Endocr Metab Dis. 2024;1:56–61
    DOI: https://doi.org/10.37349/eemd.2024.00007
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    Original Article
    Epigenetics in etiopathology of hyperprolactinemia
    Aim: Epigenetic alterations have been reported in patients with pituitary tumors and those on antipsychotic drugs, which are also responsible for hyperprolactinemia. This suggests a possible role [...] Read more.
    Amanpreet Kaur Kalsi ... Jai Bhagwan Sharma
    Published: May 22, 2024 Explor Endocr Metab Dis. 2024;1:39–55
    DOI: https://doi.org/10.37349/eemd.2024.00006
    This article belongs to the special issue The HPA Axis in Health and Disease
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    Times Cited: 0