• 10 results in Exploration of Drug Science
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    Open Access
    Editorial
    Drug discovery: a multifactorial ecosystem
    Fernando Albericio
    Published: January 01, 2023 Explor Drug Sci. 2023;1:1–5
    DOI: https://doi.org/10.37349/eds.2022.00001
    View:602
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    Times Cited: 0
    Open Access
    Original Article
    Convenient estimation of oxytetracycline and polymyxin B by a novel high-performance liquid chromatography method: development and validation
    Aim: The aim of this research work was to develop a validated reversed-phase (RP)-high-performance liquid chromatography (HPLC) method for simultaneous estimation of oxytetracycline (OXY) and pol [...] Read more.
    Tanu Chaudhary ... Dilpreet Singh
    Published: February 24, 2023 Explor Drug Sci. 2023;1:6–17
    DOI: https://doi.org/10.37349/eds.2023.00002
    View:151
    Download:16
    Times Cited: 0
    Open Access
    Original Article
    Surface functionalized mesoporous polydopamine nanocomposites for killing tumor cells through collaborative chemo/photothermal/chemodynamic treatment
    Aim: The development of a collaborative strategy with improved efficacy holds great promise in tumor treatment. This study aims to develop an effective collaborative strategy based on functionalized mesoporous polydopamine (MPDA)  [...] Read more.
    Yi Ouyang ... Hui Liu
    Published: February 27, 2023 Explor Drug Sci. 2023;1:18–30
    DOI: https://doi.org/10.37349/eds.2023.00003
    This article belongs to the special issue Emerging Nanomedicine Technologies for Enhanced Cancer Theranostics
    View:219
    Download:14
    Times Cited: 0
    Open Access
    Review
    Essential functions, syntheses and detection of sialyl Lewis X on glycoproteins
    It is widely acknowledged that sialyl Lewis X (sLeX), the composition and linkage of which are N-acetylneuraminic acid (Neu5Ac) α2-3 galactose (Gal) β1-4 [fucose (Fuc) α1-3] N-acetylglucosamine, is usually attached to the cell  [...] Read more.
    Qiushi Chen ... Xuechen Li
    Published: February 28, 2023 Explor Drug Sci. 2023;1:31–54
    DOI: https://doi.org/10.37349/eds.2023.00004
    This article belongs to the special issue Bioactive Peptides discovery and development
    View:355
    Download:23
    Times Cited: 0
    Open Access
    Systematic Review
    Utilizing the Ethereum blockchain for retrieving and archiving augmented reality surgical navigation data
    Aim: Conventional techniques to share and archive spinal imaging data raise issues with trust and security, with novel approaches being more greatly considered. Ethereum smart contracts present o [...] Read more.
    Sai Batchu ... Brandon Lucke-Wold
    Published: February 28, 2023 Explor Drug Sci. 2023;1:55–63
    DOI: https://doi.org/10.37349/eds.2023.00005
    View:254
    Download:15
    Times Cited: 0
    Open Access
    Original Article
    Levistolide A and periplogenin inhibit the growth of gastric cancer cells in vitro and in vivo
    Aim: In the present study, the natural products levistolide A (LA) and periplogenin (PPG) were studied for their growth inhibitory effects on the development of gastric cancer cells in vitro and,  [...] Read more.
    Jia Li Guo ... Ji Zhong Zhao
    Published: March 30, 2023 Explor Drug Sci. 2023;1:64–76
    DOI: https://doi.org/10.37349/eds.2023.00006
    This article belongs to the special issue Exploring Potential Drugs from Natural Products
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    Times Cited: 0
    Open Access
    Editorial
    Machine learning for drug science
    Walter F. de Azevedo Jr.
    Published: April 16, 2023 Explor Drug Sci. 2023;1:77–80
    DOI: https://doi.org/10.37349/eds.2023.00007
    This article belongs to the special issue Machine Learning for Drug Science
    View:134
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    Times Cited: 0
    Open Access
    Review
    Focused ultrasound for treatment of peripheral brain tumors
    Malignant brain tumors are the leading cause of cancer-related death in children and remain a significant cause of morbidity and mortality throughout all demographics. Central nervous system (CNS) t [...] Read more.
    Phillip Mitchell Johansen ... Brandon Lucke-Wold
    Published: April 28, 2023 Explor Drug Sci. 2023;1:107–125
    DOI: https://doi.org/10.37349/eds.2023.00009
    View:193
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    Times Cited: 0
    Open Access
    Review
    Nano theranostics involved in bladder cancer treatment
    Bladder cancer (BC) is a complex disease with multiple clinical manifestations and treatment challenges, and current standard-of-care therapies remain limited and unfavorable. Theranostics, the inte [...] Read more.
    Kunpeng Liu ... Qingsong Yu
    Published: April 28, 2023 Explor Drug Sci. 2023;1:81–106
    DOI: https://doi.org/10.37349/eds.2023.00008
    This article belongs to the special issue Emerging Nanomedicine Technologies for Enhanced Cancer Theranostics
    View:182
    Download:8
    Times Cited: 0
    Open Access
    Original Article
    Heterogeneous graph convolutional neural network for protein-ligand scoring
    Aim: Drug discovery is a long process, often taking decades of research endeavors. It is still an active area of research in both academic and industrial sectors with efforts on reducing time and [...] Read more.
    Kevin Crampon ... Luiz Angelo Steffenel
    Published: April 30, 2023 Explor Drug Sci. 2023;1:126–139
    DOI: https://doi.org/10.37349/eds.2023.00010
    This article belongs to the special issue Machine Learning for Drug Science
    View:146
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    Times Cited: 0