• All
  • Article Title
  • Abstract
  • Keywords
  • Author
  • Institution
  • 113 results in Exploration of Drug Science
    Sort by
    Most Cited
    Open Access
    Review
    A review of the effects of pharmaceutical pollutants on humans and aquatic ecosystem
    The presence of high-quality water is essential not only for human survival but also for the well-being of plants and animals. This research aimed to examine studies investigating the occurrence of  [...] Read more.
    Jaya Vinny Eapen ... Jayesh Antony
    Published: August 28, 2024 Explor Drug Sci. 2024;2:484–507
    DOI: https://doi.org/10.37349/eds.2024.00058
    View:13139
    Download:279
    Open Access
    Review
    Seaweed: a sustainable solution for greening drug manufacturing in the pursuit of sustainable healthcare
    The environmental impact of drug manufacturing raises concerns about sustainability in healthcare. To address this, exploring alternative approaches to drug production is crucial. This review focuse [...] Read more.
    Leonel Pereira, João Cotas
    Published: February 27, 2024 Explor Drug Sci. 2024;2:50–84
    DOI: https://doi.org/10.37349/eds.2024.00036
    This article belongs to the special issue Greening Drug Manufacturing for a Sustainable Healthcare
    View:9203
    Download:173
    Open Access
    Review
    Antioxidants from microalgae and their potential impact on human well-being
    In recent times, there has been a revolutionary surge in antioxidant research, with a focus on harnessing microalgae to enhance wellness and extend human longevity. Microalgae, a diverse group of un [...] Read more.
    Leonel Pereira ... Ana Valado
    Published: May 31, 2024 Explor Drug Sci. 2024;2:292–321
    DOI: https://doi.org/10.37349/eds.2024.00048
    This article belongs to the special issue Greening Drug Manufacturing for a Sustainable Healthcare
    View:7211
    Download:216
    Open Access
    Review
    Nature-inspired and medicinally relevant short peptides
    Peptides constitute an important component of Nature’s pharmacy and they play a significant role in several signaling pathways acting as natural biological messengers. While nature has mastered th [...] Read more.
    Maria G. Ciulla ... Kamal Kumar
    Published: June 27, 2023 Explor Drug Sci. 2023;1:140–171
    DOI: https://doi.org/10.37349/eds.2023.00011
    This article belongs to the special issue Exploring Potential Drugs from Natural Products
    View:9025
    Download:282
    Open Access
    Review
    The protective role of GLP-1 in neuro-ophthalmology
    Despite recent advancements in the field of neuro-ophthalmology, the rising rates of neurological and ophthalmological conditions, mismatches between supply and demand of clinicians, and an aging po [...] Read more.
    Sohum Sheth ... Brandon Lucke-Wold
    Published: August 28, 2023 Explor Drug Sci. 2023;1:221–238
    DOI: https://doi.org/10.37349/eds.2023.00015
    View:8265
    Download:193
    Open Access
    Review
    Therapeutic proteins immunogenicity: a peptide point of view
    Protein therapeutics are extensively used in the treatment of autoimmune diseases, but a subset of patients appears to be refractory to these treatments, mainly due to the development of an immune r [...] Read more.
    Feliciana Real-Fernandez ... Paolo Rovero
    Published: October 26, 2023 Explor Drug Sci. 2023;1:377–387
    DOI: https://doi.org/10.37349/eds.2023.00025
    This article belongs to the special issue Bioactive Peptides discovery and development
    View:4459
    Download:133
    Open Access
    Review
    Harnessing the power of seaweed: unveiling the potential of marine algae in drug discovery
    Seaweeds, also known as marine algae, have gained attention as a promising source of bioactive compounds with potential applications in drug discovery. This review explores the emerging field of sea [...] Read more.
    Leonel Pereira, Ana Valado
    Published: December 28, 2023 Explor Drug Sci. 2023;1:475–496
    DOI: https://doi.org/10.37349/eds.2023.00032
    View:6119
    Download:168
    Open Access
    Review
    Approved antibacterial drugs in the last 10 years: from the bench to the clinic
    Bacterial infections constitute one of the major cases of primary medical incidences worldwide. Historically, the fight against bacterial infections in humans has been an ongoing battle, due to the  [...] Read more.
    Miguel García-Castro ... Juan Manuel López-Romero
    Published: June 30, 2023 Explor Drug Sci. 2023;1:180–209
    DOI: https://doi.org/10.37349/eds.2023.00013
    This article belongs to the special issue Exploring Potential Drugs from Natural Products
    View:11469
    Download:314
    Open Access
    Review
    Phytochemicals for mitigating the COVID-19 crisis: evidence from pre-clinical and clinical studies
    The outbreak of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection in December 2019 quickly escalated to pandemic levels and had a severe impact on public health. There are 761 m [...] Read more.
    Atri Das ... Shantanabha Das
    Published: October 24, 2023 Explor Drug Sci. 2023;1:336–376
    DOI: https://doi.org/10.37349/eds.2023.00024
    This article belongs to the special issue Exploring Potential Drugs from Natural Products
    View:4147
    Download:89
    Open Access
    Systematic Review
    Utilizing the Ethereum blockchain for retrieving and archiving augmented reality surgical navigation data
    Aim: Conventional techniques to share and archive spinal imaging data raise issues with trust and security, with novel approaches being more greatly considered. Ethereum smart contracts present o [...] Read more.
    Sai Batchu ... Brandon Lucke-Wold
    Published: February 28, 2023 Explor Drug Sci. 2023;1:55–63
    DOI: https://doi.org/10.37349/eds.2023.00005
    View:2454
    Download:46
    Open Access
    Review
    Focused ultrasound for treatment of peripheral brain tumors
    Malignant brain tumors are the leading cause of cancer-related death in children and remain a significant cause of morbidity and mortality throughout all demographics. Central nervous system (CNS) t [...] Read more.
    Phillip Mitchell Johansen ... Brandon Lucke-Wold
    Published: April 28, 2023 Explor Drug Sci. 2023;1:107–125
    DOI: https://doi.org/10.37349/eds.2023.00009
    View:4878
    Download:80
    Open Access
    Original Article
    Late-stage diversification strategy for the synthesis of peptide acids and amides using hydrazides
    Aim: Modification of the C-terminus of a peptide to improve its properties, particularly after constructing the peptide chain, has great promise in the development of peptide therapeutics. This s [...] Read more.
    Shoko Tanaka ... Kohei Sato
    Published: October 09, 2023 Explor Drug Sci. 2023;1:322–335
    DOI: https://doi.org/10.37349/eds.2023.00023
    This article belongs to the special issue Bioactive Peptides discovery and development
    View:2708
    Download:79
    Open Access
    Review
    Influenza A virus hemagglutinin: from classical fusion inhibitors to proteolysis targeting chimera-based strategies in antiviral drug discovery
    The influenza virus glycoprotein hemagglutinin (HA) participates in critical steps of the attachment of viral particles to the host cell membrane receptor and membrane fusion. Due to its crucial inv [...] Read more.
    Francisco Javier Hermoso-Pinilla ... Francisco Javier Luque
    Published: February 29, 2024 Explor Drug Sci. 2024;2:85–116
    DOI: https://doi.org/10.37349/eds.2024.00037
    View:3384
    Download:111
    Open Access
    Mini Review
    Mini-review on the antimicrobial potential of actinobacteria associated with seagrasses
    The search for novel therapeutic agents to combat the crisis of antimicrobial resistance has spanned from terrestrial to unique, marine environments. Currently, most of the drugs available for usage [...] Read more.
    Galana Siro, Atanas Pipite
    Published: February 29, 2024 Explor Drug Sci. 2024;2:117–125
    DOI: https://doi.org/10.37349/eds.2024.00038
    This article belongs to the special issue Exploring Potential Drugs from Natural Products
    View:2154
    Download:56
    Open Access
    Review
    Harnessing the immunomodulatory potential of natural products in precision medicine—a comprehensive review
    Traditional medicine systems worldwide utilize natural products (NPs), including plant-derived compounds, minerals, and organisms, harnessing their healing potential. NPs offer a rich source of pote [...] Read more.
    Maya G. Pillai, Helen Antony
    Published: June 27, 2024 Explor Drug Sci. 2024;2:339–360
    DOI: https://doi.org/10.37349/eds.2024.00050
    This article belongs to the special issue Exploring Potential Drugs from Natural Products
    View:2973
    Download:61
    Open Access
    Review
    Nano theranostics involved in bladder cancer treatment
    Bladder cancer (BC) is a complex disease with multiple clinical manifestations and treatment challenges, and current standard-of-care therapies remain limited and unfavorable. Theranostics, the inte [...] Read more.
    Kunpeng Liu ... Qingsong Yu
    Published: April 28, 2023 Explor Drug Sci. 2023;1:81–106
    DOI: https://doi.org/10.37349/eds.2023.00008
    View:3077
    Download:61
    Open Access
    Review
    Electrospun short fibers: a new platform for cancer nanomedicine applications
    With the continuous development of nanomaterials, nanofibers prepared by electrospinning have gradually occupied people’s vision because of their unique advantages, such as crisscross network and  [...] Read more.
    Yifan Huang ... Xiangyang Shi
    Published: December 27, 2023 Explor Drug Sci. 2023;1:454–467
    DOI: https://doi.org/10.37349/eds.2023.00030
    View:2158
    Download:48
    Open Access
    Review
    Effect of the size of nucleic acid delivery systems on their fate in cancer treatment
    Nucleic acid therapeutics are emerging as a promising class of medicines, offering unique therapeutic options for cancer at the gene level. However, the druggability of nucleic acid therapeutics is  [...] Read more.
    Mengyun Ye ... Dandan Zhu
    Published: February 01, 2024 Explor Drug Sci. 2024;2:38–49
    DOI: https://doi.org/10.37349/eds.2024.00035
    View:1617
    Download:30
    Open Access
    Short Communication
    FDA’s approval of resmetirom (Rezdiffra): a breakthrough in MASH management
    The FDA’s approval of resmetirom (Rezdiffra) marks a significant breakthrough in treating metabolic dysfunction-associated steatohepatitis (MASH) and fibrosis, conditions linked to non-alcoholic f [...] Read more.
    Muhammad Mazhar Azam ... Bibek Giri
    Published: December 03, 2024 Explor Drug Sci. 2024;2:867–874
    DOI: https://doi.org/10.37349/eds.2024.00078
    View:8096
    Download:85
    Open Access
    Review
    Lipopeptide adjuvants for antibiotics and vaccines: the future step in the fight against multidrug-resistant and extensively drug-resistant pathogens
    With the surge of antibiotic resistance in bacteria, the need for a larger arsenal of effective antibiotics and vaccines has drastically increased in the past decades. Antibiotics like vaccines can  [...] Read more.
    Chloé O. Sebilleau, Steven J. Sucheck
    Published: April 29, 2024 Explor Drug Sci. 2024;2:203–233
    DOI: https://doi.org/10.37349/eds.2024.00043
    This article belongs to the special issue Bioactive Peptides discovery and development
    View:2635
    Download:47