• Special Issue Topic

    Exploring Potential Drugs from Natural Products

    Submission Deadline: March 31, 2024

    Guest Editor

    Prof. Juergen Reichardt E-Mail

    Australian Institute of Tropical Health and Medicine (AITHM), James Cook University, Smithfield QLD, Australia

    Research Keywords: human genetics; human genomics; biochemistry; pharmacogenetics; molecular biology

    About the Special Issue

    Biodiversity is under threat worldwide which may well rob humankind if not all life forms of a valuable asset. This applies universally from subsistence farming to recreation but also specifically to the potential drugs residing unexplored in natural products on land, in the seas and in the air. This special issue will address such undiscovered compounds, strategies to identify them and to uncover potential targets, mechanisms of action and therapeutic uses.

    Particular areas of interest include organic chemistry, biochemistry, mechanisms of action and more of potential drugs from natural products. Other foci of interest include strategies for the identification of relevant compounds, drug targets and mechanisms of action of potential drugs derived from natural products as well as the structures, biosynthesis, metabolism etc. of these chemicals.

    Call for Papers

    Published Articles

    Open Access
    Mini Review
    Mini-review on the antimicrobial potential of actinobacteria associated with seagrasses
    The search for novel therapeutic agents to combat the crisis of antimicrobial resistance has spanned from terrestrial to unique, marine environments. Currently, most of the drugs available for usage [...] Read more.
    Galana Siro, Atanas Pipite
    Published: February 29, 2024 Explor Drug Sci. 2024;2:117–125
    DOI: https://doi.org/10.37349/eds.2024.00038
    Times Cited: 0
    Open Access
    Phytochemicals for mitigating the COVID-19 crisis: evidence from pre-clinical and clinical studies
    The outbreak of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection in December 2019 quickly escalated to pandemic levels and had a severe impact on public health. There are 761 m [...] Read more.
    Atri Das ... Shantanabha Das
    Published: October 24, 2023 Explor Drug Sci. 2023;1:336–376
    DOI: https://doi.org/10.37349/eds.2023.00024
    Open Access
    Natural compounds from medicinal plants against COVID-19
    The severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2), known to cause the coronavirus disease 2019 (COVID-19), was declared a pandemic in early 2020. During the past time, several infecti [...] Read more.
    Anton Kolodnitsky ... Vladimir Poroikov
    Published: August 28, 2023 Explor Drug Sci. 2023;1:253–275
    DOI: https://doi.org/10.37349/eds.2023.00017
    Times Cited: 0
    Open Access
    Approved antibacterial drugs in the last 10 years: from the bench to the clinic
    Bacterial infections constitute one of the major cases of primary medical incidences worldwide. Historically, the fight against bacterial infections in humans has been an ongoing battle, due to the  [...] Read more.
    Miguel García-Castro ... Juan Manuel López-Romero
    Published: June 30, 2023 Explor Drug Sci. 2023;1:180–209
    DOI: https://doi.org/10.37349/eds.2023.00013
    Open Access
    Original Article
    Identification of an inter-cysteine loop potentially involved in the activity of Opisthorchis viverrini-granulin-1
    Aim: Identification of small bioactive regions in proteins and peptides can be useful information in drug design studies. The current study has shown that an inter-cysteine loop of the N-terminal [...] Read more.
    Rozita Takjoo ... Norelle L. Daly
    Published: June 30, 2023 Explor Drug Sci. 2023;1:172–179
    DOI: https://doi.org/10.37349/eds.2023.00012
    Times Cited: 0
    Open Access
    Nature-inspired and medicinally relevant short peptides
    Peptides constitute an important component of Nature’s pharmacy and they play a significant role in several signaling pathways acting as natural biological messengers. While nature has mastered th [...] Read more.
    Maria G. Ciulla ... Kamal Kumar
    Published: June 27, 2023 Explor Drug Sci. 2023;1:140–171
    DOI: https://doi.org/10.37349/eds.2023.00011
    Open Access
    Original Article
    Levistolide A and periplogenin inhibit the growth of gastric cancer cells in vitro and in vivo
    Aim: In the present study, the natural products levistolide A (LA) and periplogenin (PPG) were studied for their growth inhibitory effects on the development of gastric cancer cells in vitro and,  [...] Read more.
    Jia Li Guo ... Ji Zhong Zhao
    Published: March 30, 2023 Explor Drug Sci. 2023;1:64–76
    DOI: https://doi.org/10.37349/eds.2023.00006
    Times Cited: 0