• Special Issue Topic

    Remedial benefits of natural products in inflammation and cancer

    Submission Deadline: July 31, 2024

    Guest Editors

    Noah Isakov E-Mail

    Department of Microbiology, Immunology and Genetics Ben Gurion University of the Negev, Beer Sheva, Israel

    Research Keywords: cancer immunobiology; T cell activation; signal transduction; protooncogenes; adaptor proteins; kinase; phosphatase; isomerase


    Ruby John Anto E-Mail

    Molecular Bioassay Laboratory, Institute of Advanced Virology, Thiruvananthapuram, India

    Research Keywords: bioprospecting for anticancer molecules; chemosensitization; chemoprevention; carcinogenesis; chemotherapeutics


    About the Special Issue

    The utilization of natural products as remedies for the treatment of a wide range of diseases has been practiced since ancient times. The earliest indication of human use of natural products was found in the cuneiform writing on clay tablets, dating to circa 2600 B.C, illustrating that people from the Near East region of Mesopotamia had been making use of the health benefits of oil extracts from plants such as Cypress (Cupressus sempervirens) and Myrrh (Commiphora), to relieve conditions like cough and inflammation. Interestingly, these extracts are still being used today as remedies for these illnesses. Over the past few decades, tremendous effort has gone into isolating and characterizing novel natural compounds from plants, animals, and other living organisms. Ethno pharmacological studies and more recent usage of cutting-edge molecular technologies, have led to the discovery of numerous active natural compounds and structurally related analogues. Some of these compounds are currently being used as effective medications for the treatment of distinct types of cancers as well as inflammatory and infectious diseases.

    This Special Issue on Remedial benefits of natural products in inflammation and cancer is devoted to in-depth research on natural products, descriptions of their biological effects, evaluation of their therapeutic properties, and investigation of their mechanisms of action.

    Areas of interest include, but are not limited to:
    Discovery, identification, and characterization of natural products
    Technological advances in the discovery of drugs derived from natural products
    Pharmacological models in the study of natural products
    The therapeutic benefits of natural products and their derivatives
    Effect of natural products on immune functions and anti-cancer responses

    Both original research papers and review manuscripts are welcome.

    Keywords: natural products; plant extract; bioactive compound; remedies; drug discovery; cancer; inflammation

    Call for Papers

    Published Articles

    Open Access
    Perspective
    Plants and fungi metabolites as novel autophagy inducers and senescence inhibitors
    Premature aging can be partially explained by inefficient autophagy (the process of cellular self-digestion that recycles intracellular components) and premature senescence (cease of cellular divisi [...] Read more.
    Rivka Ofir
    Published: July 01, 2024 Explor Drug Sci. 2024;2:361–368
    DOI: https://doi.org/10.37349/eds.2024.00051
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