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    Bioactive Peptides discovery and development

    Submission Deadline: June 30, 2023

    Guest Editor

    Prof. Xuechen Li E-Mail

    Professor of Department of Chemistry, The University of Hong Kong, Hong Kong, China

    Research Keywords: synthetic protein; antibiotics; glycoconjugates; drug conjugates


    About the Special Issue

    Peptides have emerged as an exciting therapeutic modality with middle-sized molecular weights and pharmacological properties in between traditional small molecule drugs and therapeutic proteins. Many peptide drugs have been clinically used for various diseases, including antimicrobial peptides, supplementary peptide hormones, peptide-drug conjugates and so on. In addition, peptides hold great promise for disrupting protein-protein interactions (PPIs) and drug delivery.

    The past decades have witnesses great advances in bioactive peptides discovery and development. For instance,  genome mining has led to many new ribosomally synthesized and post-translationally modified peptides (RiPPs), various chemical methods have been developed to effectively cyclize peptides, peptide ligation allows for efficient synthesis of long peptides, super diverse peptide libraries provide powerful tools for high throughput screening and new knowledges have been gained for peptide intracellular delivery. 

    This special issue calls for the submission in all aspect in peptides, including, but not limited to, new bioactive peptide discovery, biosynthesis, peptide synthesis, peptide delivery, cyclic peptides, peptide-drug conjugates, medicinal chemistry, etc

    Keywords: bioactive peptide, peptide synthesis, ribosomally synthesized and post-translationally modified peptides, peptide conjugates, peptide delivery, peptide high throughput screening

    Call for Papers

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    • Ongoing Special Issues
      Exploring Potential Drugs from Natural Products
      Machine Learning for Drug Science
      Emerging Nanomedicine Technologies for Enhanced Cancer Theranostics
      Bioactive Peptides discovery and development
      Drug Discovery in Neuropsychiatric Diseases: therapeutic opportunities beyond the classic aminergic system
      Preventive and Therapeutic Potential of Nutraceuticals in Non-communicable Diseases
      Exploration of Emerging Treatments for Neurotrauma
      Greening Drug Manufacturing for a Sustainable Healthcare
      Innovative Therapeutics in Hepato-Gastroenterology
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