• 39 results in Exploration of Digestive Diseases
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    The central role of mitochondrial metabolism in hepatic steatosis
    Mitochondria are present in all mammalian cells except matured red blood cells. Mitochondria consist of several metabolic pathways for glucose, fatty acids, amino acids, and bioenergetic pathways fo [...] Read more.
    Sanda Win ... Filbert Win Min Aung
    Published: February 29, 2024 Explor Dig Dis. 2024;3:42–68
    DOI: https://doi.org/10.37349/edd.2024.00039
    This article belongs to the special issue Mitochondria and Lipid Signalling in Liver Diseases
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    Review
    SERPINB3 in fibrogenic chronic liver diseases and primary liver cancers
    Chronic liver diseases (CLDs), which are typically characterized by fibrogenic progression towards liver cirrhosis and related complications eventually leading to organ failure and can also lead to  [...] Read more.
    Patrizia Pontisso, Maurizio Parola
    Published: February 28, 2024 Explor Dig Dis. 2024;3:22–41
    DOI: https://doi.org/10.37349/edd.2024.00038
    This article belongs to the special issue Fibrosis and Hepatobiliary Cancer
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    Review
    Bile as a liquid biopsy matrix: potential applications and limitations
    Hunting for tumoral material in body fluids, traditionally in blood, the so-called liquid biopsy is set to revolutionize the diagnosis and management of oncological patients. However, other biofluid [...] Read more.
    Maria Arechederra ... Carmen Berasain
    Published: February 04, 2024 Explor Dig Dis. 2024;3:5–21
    DOI: https://doi.org/10.37349/edd.2024.00037
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    Editorial
    Precision medicine in chemotherapy: Is there room for advancement in colorectal cancer?
    Michele Ghidini
    Published: January 18, 2024 Explor Dig Dis. 2024;3:2–4
    DOI: https://doi.org/10.37349/edd.2024.00036
    This article belongs to the special issue Latest Updates in the Endoscopic, Surgical and Medical Treatment of Resectable and Advanced Gastrointestinal Cancers
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    Correction
    Correction: Familial achalasia isolated or syndromic: about 18 families
    Editorial Office
    Published: January 11, 2024 Explor Dig Dis 2024;3:1
    DOI: https://doi.org/10.37349/edd.2024.00035
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    Review
    Deciphering the liver enigma: distinguishing drug-induced liver injury and metabolic dysfunction-associated steatotic liver disease—a comprehensive narrative review
    Drug-induced liver injury (DILI) poses a complex and heterogeneous clinical challenge, which often resembles non-drug related acute or chronic liver diseases, such as metabolic dysfunction-associate [...] Read more.
    Miren García-Cortés ... Alberto García-García
    Published: December 27, 2023 Explor Dig Dis 2023;2:318–336
    DOI: https://doi.org/10.37349/edd.2023.00034
    This article belongs to the special issue Drug-induced Liver Injury: From Bench to Clinical Application
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    Original Article
    The significance of chronic hyperglycemia for the reduced efficacy of eradication therapy in patients with type 2 diabetes mellitus and for Helicobacter pylori survival
    Aim: This study aims to determine the significance of chronic hyperglycemia for the reduced efficacy of eradication therapy in patients with type 2 diabetes mellitus (T2DM) and Helicobacter pylor [...] Read more.
    Luiza Gilmanovna Bektemirova ... Vasiliy Ivanovich Reshetnyak
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    Original Article
    Impact of the direct acting antivirals on chronic hepatitis C prevalence on the Swiss organ transplantation list: a retrospective analysis
    Aim: In Switzerland, the first access to interferon-free direct-acting antivirals (DAAs) for hepatitis C virus (HCV) treatment was in 2014. This study aimed to analyze the effects of DAAs on the  [...] Read more.
    Luis Falcato ... Franz Immer
    Published: December 25, 2023 Explor Dig Dis. 2023;2:297–304
    DOI: https://doi.org/10.37349/edd.2023.00032
    This article belongs to the special issue Chronic Hepatitis B and C
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    Review
    Therapeutic targets for metabolic dysfunction-associated steatotic liver disease and their roles in hepatocellular carcinoma
    Metabolic dysfunction-associated steatotic liver disease (MASLD) is one of the most common chronic liver diseases. Over time, there has been a significant increase in the prevalence of MASLD. It has [...] Read more.
    Chenyu Wei ... Xianguang Yang
    Published: December 13, 2023 Explor Dig Dis. 2023;2:282–296
    DOI: https://doi.org/10.37349/edd.2023.00031
    This article belongs to the special issue Cellular and Molecular Targets for NAFLD or MAFLD Treatments and Their Functions in Liver Fibrosis, Cirrhosis, and Cancer
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    Original Article
    Familial achalasia isolated or syndromic: about 18 families
    Aim: Familial achalasia (FA) is a very rare condition. This work aims to evaluate its prevalence, characterize its clinical profile in a large series, and assess the efficacy and safety of pneuma [...] Read more.
    Amar Tebaibia ... Nadia Oumnia
    Published: October 26, 2023 Explor Dig Dis. 2023;2:276–281
    DOI: https://doi.org/10.37349/edd.2023.00030
    This article belongs to the special issue Advances in Hepato-gastroenterology: Diagnosis, Prognostication, and Disease Stratification
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