• 6 results in Exploration of Drug Science
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    Original Article
    Creation and interpretation of machine learning models for aqueous solubility prediction
    Aim: Solubility prediction is an essential factor in rational drug design and many models have been developed with machine learning (ML) methods to enhance the predictive ability. However, most o [...] Read more.
    Minyi Su, Enric Herrero
    Published: October 30, 2023 Explor Drug Sci. 2023;1:388–404
    DOI: https://doi.org/10.37349/eds.2023.00026
    This article belongs to the special issue Machine Learning for Drug Science
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    Open Access
    Review
    Therapeutic proteins immunogenicity: a peptide point of view
    Protein therapeutics are extensively used in the treatment of autoimmune diseases, but a subset of patients appears to be refractory to these treatments, mainly due to the development of an immune r [...] Read more.
    Feliciana Real-Fernandez ... Paolo Rovero
    Published: October 26, 2023 Explor Drug Sci. 2023;1:377–387
    DOI: https://doi.org/10.37349/eds.2023.00025
    This article belongs to the special issue Bioactive Peptides discovery and development
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    Open Access
    Review
    Phytochemicals for mitigating the COVID-19 crisis: evidence from pre-clinical and clinical studies
    The outbreak of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection in December 2019 quickly escalated to pandemic levels and had a severe impact on public health. There are 761 m [...] Read more.
    Atri Das ... Shantanabha Das
    Published: October 24, 2023 Explor Drug Sci. 2023;1:336–376
    DOI: https://doi.org/10.37349/eds.2023.00024
    This article belongs to the special issue Exploring Potential Drugs from Natural Products
    Open Access
    Original Article
    Late-stage diversification strategy for the synthesis of peptide acids and amides using hydrazides
    Aim: Modification of the C-terminus of a peptide to improve its properties, particularly after constructing the peptide chain, has great promise in the development of peptide therapeutics. This s [...] Read more.
    Shoko Tanaka ... Kohei Sato
    Published: October 09, 2023 Explor Drug Sci. 2023;1:322–335
    DOI: https://doi.org/10.37349/eds.2023.00023
    This article belongs to the special issue Bioactive Peptides discovery and development
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    Times Cited: 0
    Open Access
    Case Report
    Grade IV oral mucositis treatment with Brazilian green propolis mucoadherent gel
    Green propolis is collected by Apis mellifera from the flowers and buds of Baccharis dracunculifolia. It has several chemical compounds that confer anti-inflammatory, antimicrobial, healing, and ant [...] Read more.
    Diogo Alvarenga Silva ... Vagner Rodrigues Santos
    Published: October 9, 2023 Explor Drug Sci. 2023;1:312–321
    DOI: https://doi.org/10.37349/eds.2023.00022
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    Open Access
    Original Article
    Electrochemical properties of hydroxyapatite immobilization material for potential cytosensor fabrication
    Aim: The biorecognition unit of an electrochemical biosensor requires molecules that are immobilised to serve as a bridge between the recognition unit and the transducing surface. Unique material [...] Read more.
    Dennis Adusei ... Elvis K. Tiburu
    Published: September 21, 2023 Explor Drug Sci. 2023;1:299–311
    DOI: https://doi.org/10.37349/eds.2023.00021
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    Times Cited: 0