• 92 results in Exploration of Neuroprotective Therapy
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    Protein kinases as therapeutic targets for Alzheimer’s disease: a brief review
    Alzheimer’s disease (AD) is a progressive and incurable neurodegenerative disorder, with an unknown etiology and a multifactorial pathophysiology characterized by protein misfolding, neuroinflamma [...] Read more.
    Isabela Marie Fernandes Silva ... Claudio Viegas Jr.
    Published: October 28, 2024 Explor Neuroprot Ther. 2024;4:411–441
    DOI: https://doi.org/10.37349/ent.2024.00092
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    Open Access
    Mini Review
    Impaired glymphatic clearance is an important cause of Alzheimer’s disease
    Alzheimer’s disease (AD) is the leading cause of dementia worldwide. The disease is characterized by the abnormal accumulation of amyloid β (Aβ) protein creating neuritic plaques, hyperphosphory [...] Read more.
    Iyawnna Hazzard ... Forshing Lui
    Published: October 24, 2024 Explor Neuroprot Ther. 2024;4:401–410
    DOI: https://doi.org/10.37349/ent.2024.00091
    This article belongs to the special issue The Urgent Need for New Hypotheses to Develop Effective Therapeutic Tools Against Alzheimer's Disease
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    Open Access
    Perspective
    Reversion or compensation of mild cognitive impairment to normal cognition: strategies to prevent the development of Alzheimer’s disease continuum
    Alzheimer’s disease continuum has been described as the progressive stages of the disease over a long period. This progression can be categorized into three main stages: preclinical, mild cognitiv [...] Read more.
    Marina Avila-Villanueva, Jesús Avila
    Published: September 27, 2024 Explor Neuroprot Ther. 2024;4:392–400
    DOI: https://doi.org/10.37349/ent.2024.00090
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    Open Access
    Review
    Possible roles of heteroreceptor complexes in excitotoxic processes
    Excitotoxicity represents a neuropathological process, describing the toxic actions of excitatory neurotransmitters, where the excessive or prolonged activation of glutamate receptors triggers a cas [...] Read more.
    Diego Guidolin ... Luigi F. Agnati
    Published: September 24, 2024 Explor Neuroprot Ther. 2024;4:366–391
    DOI: https://doi.org/10.37349/ent.2024.00089
    This article belongs to the special issue GPCR Heteroreceptor Complexes as Key Players in Neuroprotection
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    Review
    Lysophospholipid receptors in neurodegeneration and neuroprotection
    The central nervous system (CNS) is one of the most complex physiological systems, and treatment of CNS disorders represents an area of major medical need. One critical aspect of the CNS is its lack [...] Read more.
    Eric Birgbauer
    Published: August 22, 2024 Explor Neuroprot Ther. 2024;4:349–365
    DOI: https://doi.org/10.37349/ent.2024.00088
    This article belongs to the special issue GPCR Heteroreceptor Complexes as Key Players in Neuroprotection
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    Open Access
    Review
    Phytocannabinoids—Evaluation of their therapeutic role in neuroinflammation
    Neuroinflammation can be caused by disease, aging, infection, brain injury, toxicity, or stress. It is a contributory factor in the neuropathology of serious conditions that include multiple scleros [...] Read more.
    Sharon Smith ... David Heal
    Published: August 22, 2024 Explor Neuroprot Ther. 2024;4:325–348
    DOI: https://doi.org/10.37349/ent.2024.00087
    This article belongs to the special issue Natural Products in Neurotherapeutic Applications
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    Letter to the Editor
    Quantitative analysis of the effects of acoustic neurostimulation on the neuropsychology of healthy adults
    To quantitatively analyze the effects of acoustic neurostimulation on the symptoms of depression, anxiety, stress, and sleep quality in healthy workers. Eleven physiological and psychological variab [...] Read more.
    Radiance C. Bouldin ... Jonghoon Kang
    Published: August 21, 2024 Explor Neuroprot Ther. 2024;4:319–324
    DOI: https://doi.org/10.37349/ent.2024.00086
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    Open Access
    Review
    An overview of the role of monoamine oxidase-B in Parkinson’s disease: implications for neurodegeneration and therapy
    Parkinson’s disease (PD) is a neurodegenerative disorder characterized by both non-motor and motor symptoms, due to the loss of dopamine-producing neurons in the brain. Monoamine oxidase-B (MAO-B) [...] Read more.
    Praveen Kumar Chandra Sekar ... Ramakrishnan Veerabathiran
    Published: July 14, 2024 Explor Neuroprot Ther. 2024;4:308–318
    DOI: https://doi.org/10.37349/ent.2024.00085
    This article belongs to the special issue Role of the Monoaminergic Systems in the Pathogenesis and the Pathophysiology of Parkinson's Disease
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    Perspective
    Vitactions: vitamins for the brain
    A novel concept has been recently put forward in the mind/body interface (https://doi.org/10.37349/ent.2024.00074). The new concept has led to a new word: vitaction. Vitactions [...] Read more.
    Rafael Franco
    Published: July 01, 2024 Explor Neuroprot Ther. 2024;4:300–307
    DOI: https://doi.org/10.37349/ent.2024.00084
    Open Access
    Review
    The potential positive effects of coenzyme Q10 on the regeneration of peripheral nerve injury
    Peripheral nerve injuries (PNIs) constitute a significant concern as they predominantly affect young and productive age groups of the population, causing social and economic pressure on patients. PN [...] Read more.
    Ahmed Mead ... Süleyman Kaplan
    Published: June 21, 2024 Explor Neuroprot Ther. 2024;4:288–299
    DOI: https://doi.org/10.37349/ent.2024.00083
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