• All
  • Article Title
  • Abstract
  • Keywords
  • Author
  • Institution
  • 94 results in Exploration of Neuroscience
    Sort by
    Most Cited
    Open Access
    Review
    Stigma and psychosocial problems in patients with epilepsy
    Epilepsy, a prevalent neurological disorder, is characterized by chronic seizures resulting from abnormal electrical activity in the brain. Adequate medical treatment allows roughly 70% of patients  [...] Read more.
    Kubra Yeni
    Published: December 06, 2023 Explor Neurosci. 2023;2:251–263
    DOI: https://doi.org/10.37349/en.2023.00026
    This article belongs to the special issue Epilepsy
    View:8826
    Download:177
    Open Access
    Review
    Neuropharmacologic modulation of the melatonergic system
    The circadian rhythm is a critical system that governs an organism’s functions in alignment with the light-dark cycle. Melatonin release from the pineal gland plays a crucial role in regulating th [...] Read more.
    Utku Aykan ... Canan Uluoglu
    Published: December 22, 2023 Explor Neurosci. 2023;2:287–306
    DOI: https://doi.org/10.37349/en.2023.00029
    This article belongs to the special issue Circadian Rhythm and Melatonin
    View:7979
    Download:70
    Open Access
    Review
    Updates in mechanical thrombectomy
    Stroke is a leading cause of morbidity and mortality. The advent of mechanical thrombectomy has largely improved patient outcomes. This article reviews the features and outcomes associated with aspi [...] Read more.
    Kevin Pierre ... Brandon Lucke-Wold
    Published: December 30, 2022 Explor Neurosci. 2022;1:83–99
    DOI: https://doi.org/10.37349/en.2022.00007
    View:5658
    Download:93
    Open Access
    Review
    Update for astrocytomas: medical and surgical management considerations
    Astrocytomas include a wide range of tumors with unique mutations and varying grades of malignancy. These tumors all originate from the astrocyte, a star-shaped glial cell that plays a major role in [...] Read more.
    Matthew Willman ... Brandon Lucke-Wold
    Published: February 23, 2023 Explor Neurosci. 2023;2:1–26
    DOI: https://doi.org/10.37349/en.2023.00009
    View:8558
    Download:102
    Open Access
    Review
    Neuroprotective prospectives of triterpenoids
    Neurological disorders including neurodegenerative disorders continue to pose significant therapeutic challenges. Triterpenoids, a diverse group of natural compounds found abundantly in plants, poss [...] Read more.
    Apoorva A. Bankar ... Nazma N. Inamdar
    Published: June 26, 2024 Explor Neurosci. 2024;3:231–254
    DOI: https://doi.org/10.37349/en.2024.00047
    This article belongs to the special issue Medicinal Plants and Bioactive Phytochemicals in Neuroprotection
    View:2655
    Download:58
    Open Access
    Review
    Current therapeutics for Alzheimer’s disease and clinical trials
    Alzheimer’s disease (AD) is a major type of dementia and neurodegenerative disease, characterized by memory loss and cognitive decline. Over decades, significant efforts have been dedicated to fin [...] Read more.
    Danqing Xiao, Chen Zhang
    Published: June 27, 2024 Explor Neurosci. 2024;3:255–271
    DOI: https://doi.org/10.37349/en.2024.00048
    This article belongs to the special issue Alzheimer’s Disease
    View:16061
    Download:255
    Open Access
    Review
    Impact of circadian clock dysfunction on human health
    All living organisms exhibit circadian rhythms. Humans show circadian rhythm of the different physiological functions such as sleep-wake cycle, core body temperature, feeding behavior, metabolic act [...] Read more.
    Saptadip Samanta, Sk Asif Ali
    Published: September 29, 2022 Explor Neurosci. 2022;1:4–30
    DOI: https://doi.org/10.37349/en.2022.00002
    This article belongs to the special issue Circadian Rhythm and Melatonin
    View:10727
    Download:169
    Open Access
    Review
    Effects mediated by melatonin and cortisol of artificial light and noise, alone and in combination, on sleep and health
    As an integral part of human chronobiology, the circadian system plays a crucial role in regulating key biological functions, including sleep and the intricate hormonal rhythms of melatonin (MLT) an [...] Read more.
    Nahum M. Gabinet
    Published: September 13, 2024 Explor Neurosci. 2024;3:382–417
    DOI: https://doi.org/10.37349/en.2024.00057
    This article belongs to the special issue Circadian Rhythm and Melatonin
    View:11496
    Download:80
    Open Access
    Review
    Connecting the ends: signaling via receptor tyrosine kinases and cytoskeletal degradation in neurodegeneration
    Receptor tyrosine kinases (RTKs) are known to perform versatile roles in disease landscapes, which determine the fate of the cell. Although much has been discussed from the perspective of proliferat [...] Read more.
    Priyanka Sengupta ... Debashis Mukhopadhyay
    Published: February 20, 2024 Explor Neurosci. 2024;3:1–26
    DOI: https://doi.org/10.37349/en.2024.00033
    This article belongs to the special issue Alzheimer’s Disease
    View:4132
    Download:71
    Open Access
    Review
    Neuregulins: subcellular localization, signaling pathways and their relationship with neuroplasticity and neurological diseases
    Neuregulins (NRGs) and their cognate ErbB receptors (ErbB2–ErbB4) constitute a vast group of proteins encoded by six different genes (NRG16) and many isoforms with critical  [...] Read more.
    Marines Longart ... Juan Carlos Martínez
    Published: September 29, 2022 Explor Neurosci. 2022;1:31–53
    DOI: https://doi.org/10.37349/en.2022.00003
    View:3460
    Download:72
    Open Access
    Review
    Therapeutic potential of extracellular vesicles in Parkinson’s disease
    Globally, the incidence of Parkinson’s disease (PD) is increasing faster than other neurodegenerative disorders. Neuropathologically, PD is characterized by the loss of dopaminergic neurons in the [...] Read more.
    Michelli Ramires Teixeira ... Rodrigo Pinheiro Araldi
    Published: June 29, 2023 Explor Neurosci. 2023;2:106–122
    DOI: https://doi.org/10.37349/en.2023.00016
    This article belongs to the special issue Extracellular Vesicles as Cell-based Therapeutics
    View:3512
    Download:70
    Open Access
    Review
    Modify gut microbiome in autism: a promising strategy?
    The gut microbiota and dysbiosis have been implicated in various metabolic diseases and gastrointestinal disorders. Recently, there has been growing evidence suggesting the influence of gut microbio [...] Read more.
    Jean Demarquoy ... Caroline Demarquoy
    Published: August 31, 2023 Explor Neurosci. 2023;2:140–152
    DOI: https://doi.org/10.37349/en.2023.00018
    View:3070
    Download:43
    Open Access
    Review
    Negative environmental influences on the developing brain mediated by epigenetic modifications
    Brain development, a complex process, consisting of several phases, starting as early as two weeks after conception, and continuing through childhood till early adolescence, is crucial for the devel [...] Read more.
    Maya Komar-Fletcher ... Joanna Michalina Jurek
    Published: September 28, 2023 Explor Neurosci. 2023;2:193–211
    DOI: https://doi.org/10.37349/en.2023.00021
    View:13359
    Download:148
    Open Access
    Review
    Investigation into the vascular contributors to dementia and the associated treatments
    As the average lifespan has increased, memory disorders have become a more pressing public health concern. However, dementia in the elderly population is often neglected in light of other health pri [...] Read more.
    Caroline Grace Davidson ... Brandon Lucke-Wold
    Published: October 15, 2023 Explor Neurosci. 2023;2:224–237
    DOI: https://doi.org/10.37349/en.2023.00023
    View:3166
    Download:46
    Open Access
    Review
    A review of epileptic markers: from ion channels, astrocytes, synaptic imbalance to whole brain network dynamics
    Epilepsy, a neurological disorder characterized by recurrent seizures, presents a complex interplay of cellular and molecular mechanisms. The symptoms manifest themselves at various scales, from ion [...] Read more.
    Swati Banerjee, Viktor Jirsa
    Published: September 29, 2024 Explor Neurosci. 2024;3:478–492
    DOI: https://doi.org/10.37349/en.2024.00060
    This article belongs to the special issue Epilepsy
    View:3764
    Download:92
    Open Access
    Review
    Neurostimulation devices to treat Alzheimer’s disease
    The use of neurostimulation devices for the treatment of Alzheimer’s disease (AD) is a growing field. In this review, we examine the mechanism of action and therapeutic indications of these neuros [...] Read more.
    Felipe P. Perez ... Maher Rizkalla
    Published: February 25, 2025 Explor Neurosci. 2025;4:100674
    DOI: https://doi.org/10.37349/en.2025.100674
    This article belongs to the special issue Alzheimer's Disease
    View:1699
    Download:33
    Open Access
    Review
    Circadian regulation of the immune-hematopoietic system
    Earth’s rotation generates the basic circadian rhythm of day and night to which all living organisms must adapt to survive. In mammals, this happens thanks to a central clock located in the suprac [...] Read more.
    Georges Maestroni
    Published: June 30, 2023 Explor Neurosci. 2023;2:123–139
    DOI: https://doi.org/10.37349/en.2023.00017
    This article belongs to the special issue Circadian Rhythm and Melatonin
    View:3872
    Download:75
    Open Access
    Original Article
    Estimation of the allelic status of apolipoprotein E4 isoforms with fully automated LUMIPULSE® assays
    Aim: Apolipoprotein E (ApoE) isoforms, especially the ApoE4 isoform, are genetic risk factors for Alzheimer’s disease (AD). Moreover, the APOE ε4 haplotype has a dose-dependent association wit [...] Read more.
    Tatsushi Yuri ... Hisashi Nojima
    Published: October 16, 2023 Explor Neurosci. 2023;2:238–244
    DOI: https://doi.org/10.37349/en.2023.00024
    This article belongs to the special issue Alzheimer’s Disease
    View:3210
    Download:75
    Open Access
    Mini Review
    Nutritional treatment with the ketogenic diet in children with refractory epilepsy: a narrative review
    The two mainstays of therapy for refractory epilepsy are medication and surgery. Child behavioral and cognitive aspects of epilepsy can be improved by using a specialized dietary regimen such as the [...] Read more.
    Srilaxmi Vityala ... Swathi Nenavath
    Published: October 30, 2023 Explor Neurosci. 2023;2:245–250
    DOI: https://doi.org/10.37349/en.2023.00025
    This article belongs to the special issue Epilepsy
    View:4393
    Download:670
    Open Access
    Review
    Inflammatory responses involved in post-cardiac arrest brain injury: mechanisms, regulation, and therapeutic potential
    Neuroinflammation plays a key role in the pathogenesis of post-cardiac arrest (CA) brain injury. Innate immune cells sense a variety of danger signals through pattern-recognition receptors and evoke [...] Read more.
    Yuzhen Zhang ... Kaibin Huang
    Published: April 26, 2023 Explor Neurosci. 2023;2:82–97
    DOI: https://doi.org/10.37349/en.2023.00014
    View:3421
    Download:80