• 6 results in Exploration of Drug Science
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    Review
    Harnessing the power of seaweed: unveiling the potential of marine algae in drug discovery
    Seaweeds, also known as marine algae, have gained attention as a promising source of bioactive compounds with potential applications in drug discovery. This review explores the emerging field of sea [...] Read more.
    Leonel Pereira, Ana Valado
    Published: December 28, 2023 Explor Drug Sci. 2023;1:475–496
    DOI: https://doi.org/10.37349/eds.2023.00032
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    Open Access
    Case Report
    Reactivation of latent hepatitis B infection during immunosuppressive therapy with guselkumab for plaque psoriasis: a case report
    Reactivation of hepatitis B virus (HBV; RHBV) is a significant concern during immunosuppressive therapy, as it can lead to severe hepatitis and liver failure. The article reports a case of RHBV duri [...] Read more.
    Elena Franchi ... Pietro Andreone
    Published: December 27, 2023 Explor Drug Sci. 2023;1:468–474
    DOI: https://doi.org/10.37349/eds.2023.00031
    This article belongs to the special issue Innovative Therapeutics in Hepato-Gastroenterology
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    Times Cited: 0
    Open Access
    Review
    Electrospun short fibers: a new platform for cancer nanomedicine applications
    With the continuous development of nanomaterials, nanofibers prepared by electrospinning have gradually occupied people’s vision because of their unique advantages, such as crisscross network and  [...] Read more.
    Yifan Huang ... Xiangyang Shi
    Published: December 27, 2023 Explor Drug Sci. 2023;1:454–467
    DOI: https://doi.org/10.37349/eds.2023.00030
    This article belongs to the special issue Emerging Nanomedicine Technologies for Enhanced Cancer Theranostics
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    Times Cited: 0
    Open Access
    Original Article
    Rational design of novel phenol ether derivatives as non-covalent proteasome inhibitors through 3D-QSAR, molecular docking and ADMET prediction
    Aim: The purpose of this paper is to use different structures and ligand-based drug design methods properly to provide theoretical guidance for the design of novel non-covalent proteasome inhibit [...] Read more.
    Miao Yuan ... Ping Cheng
    Published: December 27, 2023 Explor Drug Sci. 2023;1:435–453
    DOI: https://doi.org/10.37349/eds.2023.00029
    This article belongs to the special issue Machine Learning for Drug Science
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    Times Cited: 0
    Open Access
    Original Article
    Hybrid azole-based conjugates as upcoming anticancer and antimicrobial agents
    Aim: This study discloses the synthesis and the antimicrobial and anticancer activities of four molecules of structural basis saccharin-thiadiazolyl (4), saccharin-pyridyl (6, 8), and tetrazole-t [...] Read more.
    Luís M. T. Frija ... Patrícia Rijo
    Published: November 23, 2023 Explor Drug Sci. 2023;1:420–434
    DOI: https://doi.org/10.37349/eds.2023.00028
    This article belongs to the special issue Recent advances in hybrid molecules for drug research
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    Original Article
    Insights into the binding selectivity of harzianoic acids A and B to tetraspanin CD81
    Aim: Harzianoic acids A and B (Hz-A/B) are two rare cyclobutene-containing sesquiterpenes isolated from a marine strain of the sponge-associated fungus Trichoderma harzianum. They display anticancer and antiviral effects, r [...] Read more.
    Gérard Vergoten, Christian Bailly
    Published: November 01, 2023 Explor Drug Sci. 2023;1:405–419
    DOI: https://doi.org/10.37349/eds.2023.00027