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Exploration of Targeted Anti-tumor Therapy
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335
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Exploration of Targeted Anti-tumor Therapy
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Open Access
Review
Current strategies for the design of PROTAC linkers: a critical review
Robert I. Troup ... Matthias G. J. Baud
Published: October 30, 2020 Explor Target Antitumor Ther. 2020;1:273–312
DOI:
https://doi.org/10.37349/etat.2020.00018
This article belongs to the special issue
Proteolysis Targeting Chimera (PROTAC)
Full Text
PDF
39208
3511
262
Open Access
Review
The impact of tumour pH on cancer progression: strategies for clinical intervention
Carol Ward ... Simon P Langdon
Published: April 28, 2020 Explor Target Antitumor Ther. 2020;1:71–100
DOI:
https://doi.org/10.37349/etat.2020.00005
Full Text
PDF
25280
809
114
Open Access
Review
Early-stage triple negative breast cancer: the therapeutic role of immunotherapy and the prognostic value of pathological complete response
Pierluigi De Santis ... Palma Fedele
Published: February 28, 2024 Explor Target Antitumor Ther. 2024;5:232–250
DOI:
https://doi.org/10.37349/etat.2024.00215
This article belongs to the special issue
Innovative Strategies to Target Triple-negative Breast Cancer
Full Text
PDF
13687
233
6
Open Access
Review
Novel approaches for the rational design of PROTAC linkers
Almaz Zagidullin ... Emil Bulatov
Published: October 30, 2020 Explor Target Antitumor Ther. 2020;1:381–390
DOI:
https://doi.org/10.37349/etat.2020.00023
This article belongs to the special issue
Proteolysis Targeting Chimera (PROTAC)
Full Text
PDF
11494
533
42
Open Access
Review
Inhibitors of the Fanconi anaemia pathway as potential antitumour agents for ovarian cancer
Sarah J Taylor ... Simon P Langdon
Published: February 29, 2020 Explor Target Antitumor Ther. 2020;1:26–52
DOI:
https://doi.org/10.37349/etat.2020.00003
Full Text
PDF
10753
214
3
Open Access
Review
PROTACs are effective in addressing the platelet toxicity associated with BCL-X
L
inhibitors
Peiyi Zhang ... Guangrong Zheng
Published: August 31, 2020 Explor Target Antitumor Ther. 2020;1:259–272
DOI:
https://doi.org/10.37349/etat.2020.00017
This article belongs to the special issue
Proteolysis Targeting Chimera (PROTAC)
Full Text
PDF
10062
348
19
Open Access
Review
Development of PROTACs to address clinical limitations associated with BTK-targeted kinase inhibitors
Rachael Arthur ... Graham Packham
Published: June 29, 2020 Explor Target Antitumor Ther. 2020;1:131–152
DOI:
https://doi.org/10.37349/etat.2020.00009
This article belongs to the special issue
Proteolysis Targeting Chimera (PROTAC)
Full Text
PDF
9733
308
18
Open Access
Review
Antibody-drug conjugates: beyond current approvals and potential future strategies
Siddharth Menon ... Hui K. Gan
Published: April 28, 2022 Explor Target Antitumor Ther. 2022;3:252–277
DOI:
https://doi.org/10.37349/etat.2022.00082
This article belongs to the special issue
Antibody-Drug Conjugates
Full Text
PDF
9549
258
18
Open Access
Review
Potential benefit of β-glucans as adjuvant therapy in immuno-oncology: a review
Valeria Cognigni ... Rossana Berardi
Published: April 30, 2021 Explor Target Antitumor Ther. 2021;2:122–138
DOI:
https://doi.org/10.37349/etat.2021.00036
This article belongs to the special issue
Immunotherapy in Cancer Patients
Full Text
PDF
9120
203
13
Open Access
Review
Steroid utility, immunotherapy, and brain tumor management: an update on conflicting therapies
Matthew Goldman ... Stephan Quintin
Published: October 31, 2022 Explor Target Antitumor Ther. 2022;3:659–675
DOI:
https://doi.org/10.37349/etat.2022.00106
Full Text
PDF
8212
111
16
Open Access
Review
An overview of the anti-cancer actions of Tanshinones, derived from
Salvia miltiorrhiza
(Danshen)
Irum Naz ... Kwang Seok Ahn
Published: June 29, 2020 Explor Target Antitumor Ther. 2020;1:153–170
DOI:
https://doi.org/10.37349/etat.2020.00010
This article belongs to the special issue
Targeting Transcription Factors for Cancer Therapy
Full Text
PDF
7868
108
18
Open Access
Review
Targeting HER2 in breast cancer: new drugs and paradigms on the horizon
Paolo Tarantino ... Giuseppe Curigliano
Published: April 30, 2021 Explor Target Antitumor Ther. 2021;2:139–155
DOI:
https://doi.org/10.37349/etat.2021.00037
Full Text
PDF
7737
227
11
Open Access
Review
Nigerian medicinal plants with potential anticancer activity—a review
Mansurah A. Abdulazeez ... Amos A. Fatokun
Published: December 09, 2024 Explor Target Antitumor Ther. 2024;5:1393–1434
DOI:
https://doi.org/10.37349/etat.2024.00282
Full Text
PDF
7687
133
0
Open Access
Review
Targeted inhibition of mRNA translation initiation factors as a novel therapeutic strategy for mature B-cell neoplasms
Joe Taylor ... Graham Packham
Published: February 29, 2020 Explor Target Antitumor Ther. 2020;1:3–25
DOI:
https://doi.org/10.37349/etat.2020.00002
Full Text
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7673
130
8
Open Access
Review
The promising potential of piperlongumine as an emerging therapeutics for cancer
Dey Parama ... Ajaikumar B. Kunnumakkara
Published: August 30, 2021 Explor Target Antitumor Ther. 2021;2:323–354
DOI:
https://doi.org/10.37349/etat.2021.00049
Full Text
PDF
7593
189
14
Open Access
Review
Targeting transcription factors in cancer drug discovery
Partha Mitra
Published: December 28, 2020 Explor Target Antitumor Ther. 2020;1:401–412
DOI:
https://doi.org/10.37349/etat.2020.00025
This article belongs to the special issue
Targeting Transcription Factors for Cancer Therapy
Full Text
PDF
7586
235
4
Open Access
Review
Diagnostic value of liquid biopsy in the era of precision medicine: 10 years of clinical evidence in cancer
Vincenza Caputo ... Stefania Napolitano
Published: February 28, 2023 Explor Target Antitumor Ther 2023;4:102–138
DOI:
https://doi.org/10.37349/etat.2023.00125
This article belongs to the special issue
The Implementation of Liquid Biopsy in Clinical Practice for Different Solid Tumor
Full Text
PDF
7323
154
43
Open Access
Review
The clinical advances of proteolysis targeting chimeras in oncology
Hao Xie ... Jason B. Fleming
Published: December 31, 2021 Explor Target Antitumor Ther. 2021;2:511–521
DOI:
https://doi.org/10.37349/etat.2021.00061
This article belongs to the special issue
Proteolysis Targeting Chimera (PROTAC)
Full Text
PDF
7313
242
26
Open Access
Review
Advancing antibody-drug conjugates in gynecological malignancies: myth or reality?
Marta Nerone ... Ilaria Colombo
Published: April 19, 2022 Explor Target Antitumor Ther. 2022;3:149–171
DOI:
https://doi.org/10.37349/etat.2022.00077
This article belongs to the special issue
Antibody-Drug Conjugates
Full Text
PDF
6919
143
5
Open Access
Review
Potential of guggulsterone, a farnesoid X receptor antagonist, in the prevention and treatment of cancer
Sosmitha Girisa ... Ajaikumar B. Kunnumakkara
Published: October 30, 2020 Explor Target Antitumor Ther. 2020;1:313–342
DOI:
https://doi.org/10.37349/etat.2020.00019
This article belongs to the special issue
Targeting Transcription Factors for Cancer Therapy
Full Text
PDF
6784
81
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