| 1 |
2023 |
Qiong Li, Li Zhou, Siyuan Qin, Zhao Huang, Bowen Li, Ruolan Liu, Mei Yang, Edouard C. Nice, Huili Zhu, Canhua Huang. Proteolysis-targeting chimeras in biotherapeutics: Current trends and future applications, European Journal of Medicinal Chemistry. 2023; 257: 115447115447.
https://doi.org/10.1016/j.ejmech.2023.115447 |
| 2 |
2021 |
Santanu Hati, Marisa Zallocchi, Robert Hazlitt, Yuju Li, Sarath Vijayakumar, Jaeki Min, Zoran Rankovic, Sándor Lovas, Jian Zuo. AZD5438-PROTAC: A selective CDK2 degrader that protects against cisplatin- and noise-induced hearing loss, European Journal of Medicinal Chemistry. 2021; 226: 113849113849.
https://doi.org/10.1016/j.ejmech.2021.113849 |
| 3 |
2023 |
Qian-Qian Zhou, Hai-Tao Xiao, Fan Yang, Yong-Dan Wang, Ping Li, Zu-Guo Zheng. Advancing targeted protein degradation for metabolic diseases therapy, Pharmacological Research. 2023; 188: 106627106627.
https://doi.org/10.1016/j.phrs.2022.106627 |
| 4 |
2024 |
Nisha Setia, Haider Thaer Abdulhameed Almuqdadi, Mohammad Abid. Journey of Von Hippel-Lindau (VHL) E3 ligase in PROTACs design: From VHL ligands to VHL-based degraders, European Journal of Medicinal Chemistry. 2024; 265: 116041116041.
https://doi.org/10.1016/j.ejmech.2023.116041 |
| 5 |
2024 |
Eslam M. H. Ali, Cody A. Loy, Darci J. Trader. 2024;
https://doi.org/10.1101/2024.01.20.576376 |
| 6 |
2023 |
Yilin Gu, Yizhe Li, Jiaxing Wang, Lele Zhang, Jifa Zhang, Yuxi Wang. Targeting ferroptosis: Paving new roads for drug design and discovery, European Journal of Medicinal Chemistry. 2023; 247: 115015115015.
https://doi.org/10.1016/j.ejmech.2022.115015 |
| 7 |
2022 |
Liena Qin, Han Dai, Junfeng Wang. Key Considerations in Targeted Protein Degradation Drug Discovery and Development, Frontiers in Chemistry. 2022; 10: 934337.
https://doi.org/10.3389/fchem.2022.934337 |
| 8 |
2023 |
José A. Villegas, Tasneem M. Vaid, Michael E. Johnson, Terry W. Moore. Mapping the energy landscape of PROTAC-mediated protein-protein interactions, Computational and Structural Biotechnology Journal. 2023; 21: 1885.
https://doi.org/10.1016/j.csbj.2023.02.049 |
| 9 |
2024 |
Jingfen Su, Yue Xiao, Linyu Wei, Huiyang Lei, Fei Sun, Weixia Wang, Jun Yin, Rui Xiong, Shihong Li, Pei Zhang, Ying Zhou, Xiaochuan Wang, Jie Zheng, Jian-Zhi Wang. Generation of tau dephosphorylation-targeting chimeras for the treatment of Alzheimer’s disease and related tauopathies, Science Bulletin. 2024; 69: 1137.
https://doi.org/10.1016/j.scib.2024.01.019 |
| 10 |
2023 |
Maokai Jiang, Yuankun Wang, Yumeng Zhuang, Xianzhang Wang, Lei Yao. 2023;
https://doi.org/10.2139/ssrn.4585000 |
| 11 |
2023 |
Namy George, Md. Jawaid Akhtar, Khalid Al Balushi, Sher Zaman Safi, Syed Najmul Hejaz Azmi, Shah Alam Khan. The emerging role of proteolysis targeting chimeras (PROTACs) in the treatment of Alzheimer’s disease, Medicinal Chemistry Research. 2023;
https://doi.org/10.1007/s00044-023-03026-w |
| 12 |
2023 |
Chelsi M. Almodóvar‐Rivera, Zhen Zhang, Jingyao Li, Haibo Xie, Yu Zhao, Le Guo, Marissa G. Mannhardt, Weiping Tang. A Modular Chemistry Platform for the Development of a Cereblon E3 Ligase‐Based Partial PROTAC Library, ChemBioChem. 2023; 24: e202300482.
https://doi.org/10.1002/cbic.202300482 |
| 13 |
2023 |
Giulia Apprato, Giulia D’Agostini, Paolo Rossetti, Giuseppe Ermondi, Giulia Caron. In Silico Tools to Extract the Drug Design Information Content of Degradation Data: The Case of PROTACs Targeting the Androgen Receptor, Molecules. 2023; 28: 1206.
https://doi.org/10.3390/molecules28031206 |
| 14 |
2021 |
José A. Villegas, Tasneem M. Vaid, Michael E. Johnson, Terry W. Moore. 2021;
https://doi.org/10.1101/2021.08.31.458424 |
| 15 |
2022 |
Federica Pedrucci, Claudia Pappalardo, Giovanni Marzaro, Nicola Ferri, Alberto Ferlin, Luca De Toni. Proteolysis Targeting Chimeric Molecules: Tuning Molecular Strategies for a Clinically Sound Listening, International Journal of Molecular Sciences. 2022; 23: 6630.
https://doi.org/10.3390/ijms23126630 |
| 16 |
2021 |
Haixia Liu, Xinyu Ding, Linyi Liu, Qianglong Mi, Quanju Zhao, YuBao Shao, Chaowei Ren, Jinju Chen, Ying Kong, Xing Qiu, Nicola Elvassore, Xiaobao Yang, Qianqian Yin, Biao Jiang. Discovery of novel BCR-ABL PROTACs based on the cereblon E3 ligase design, synthesis, and biological evaluation, European Journal of Medicinal Chemistry. 2021; 223: 113645113645.
https://doi.org/10.1016/j.ejmech.2021.113645 |
| 17 |
2023 |
Anna Pasieka, Eleonora Diamanti, Elisa Uliassi, Maria Laura Bolognesi. Click Chemistry and Targeted Degradation: A Winning Combination for Medicinal Chemists?, ChemMedChem. 2023; 18: e202300422.
https://doi.org/10.1002/cmdc.202300422 |
