| 1 |
2021 |
Hannah Kiely-Collins, Georg E. Winter, Gonçalo J.L. Bernardes. The role of reversible and irreversible covalent chemistry in targeted protein degradation, Cell Chemical Biology. 2021; 28: 952.
https://doi.org/10.1016/j.chembiol.2021.03.005 |
| 2 |
2021 |
Gabriel LaPlante, Wei Zhang. Targeting the Ubiquitin-Proteasome System for Cancer Therapeutics by Small-Molecule Inhibitors, Cancers. 2021; 13: 3079.
https://doi.org/10.3390/cancers13123079 |
| 3 |
2021 |
Olga D. Jarosińska, Stefan G. D. Rüdiger. Molecular Strategies to Target Protein Aggregation in Huntington’s Disease, Frontiers in Molecular Biosciences. 2021; 8: 769184.
https://doi.org/10.3389/fmolb.2021.769184 |
| 4 |
2021 |
Ying Wang, Isabella Haight, Rishi Gupta, Anil Vasudevan. What is in Our Kit? An Analysis of Building Blocks Used in Medicinal Chemistry Parallel Libraries, Journal of Medicinal Chemistry. 2021; acs.jmedchem.1c01139.
https://doi.org/10.1021/acs.jmedchem.1c01139 |
| 5 |
2021 |
Aleša Bricelj, Yuen Lam Dora Ng, Dominic Ferber, Robert Kuchta, Sina Müller, Marius Monschke, Karl G. Wagner, Jan Krönke, Izidor Sosič, Michael Gütschow, Christian Steinebach. Influence of Linker Attachment Points on the Stability and Neosubstrate Degradation of Cereblon Ligands, ACS Medicinal Chemistry Letters. 2021; 12: 1733.
https://doi.org/10.1021/acsmedchemlett.1c00368 |
| 6 |
2021 |
Giuseppe Ermondi, Diego Garcia-Jimenez, Giulia Caron. PROTACs and Building Blocks: The 2D Chemical Space in Very Early Drug Discovery, Molecules. 2021; 26: 672.
https://doi.org/10.3390/molecules26030672 |
| 7 |
2021 |
Kunal Nepali, Jing-Ping Liou. Recent developments in epigenetic cancer therapeutics: clinical advancement and emerging trends, Journal of Biomedical Science. 2021; 28: 27.
https://doi.org/10.1186/s12929-021-00721-x |
| 8 |
2021 |
Tian Niu, Kailin Li, Li Jiang, Zhesheng Zhou, Ju Hong, Xuankun Chen, Xiaowu Dong, Qiaojun He, Ji Cao, Bo Yang, Cheng-Liang Zhu. Noncovalent CDK12/13 dual inhibitors-based PROTACs degrade CDK12-Cyclin K complex and induce synthetic lethality with PARP inhibitor, European Journal of Medicinal Chemistry. 2021; 114012114012.
https://doi.org/10.1016/j.ejmech.2021.114012 |
| 9 |
2021 |
Robert S. Foti, 2021;
https://doi.org/10.1016/B978-0-12-820472-6.00141-9 |
| 10 |
2021 |
M. Maneiro, E. De Vita, D. Conole, C.S. Kounde, Q. Zhang, E.W. Tate. Progress in Medicinal Chemistry, 2021; 60: 67.
https://doi.org/10.1016/bs.pmch.2021.01.002 |
| 11 |
2021 |
Martin Reynders, Dirk Trauner. Optical control of targeted protein degradation, Cell Chemical Biology. 2021; 28: 969.
https://doi.org/10.1016/j.chembiol.2021.05.010 |
| 12 |
2021 |
Fanwang Meng, Zhongjie Liang, Kehao Zhao, Cheng Luo. Drug design targeting active posttranslational modification protein isoforms, Medicinal Research Reviews. 2021; 41: 1701.
https://doi.org/10.1002/med.21774 |
