Exploration of Targeted Anti-tumor Therapy

Open Access Original Article

Significance of next-generation sequencing in the era of targeted therapy for biliary tract cancer: an analysis at a single institution

Kei Nakagawa ... Michiaki Unno

Published: September 18, 2026 Explor Target Antitumor Ther. 2026;7:1002402

DOI: https://doi.org/10.37349/etat.2026.1002402

This article belongs to the special issue Targeted and Precision Therapy for Adult Hepatopancreatobiliary Cancers and Liver Metastases

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Open Access Review

Cardiotoxicity in breast cancer patients treated with chemoradiotherapy

Peter Emerson, Liza Thomas

Published: September 14, 2026 Explor Target Antitumor Ther. 2026;7:1002401

DOI: https://doi.org/10.37349/etat.2026.1002401

This article belongs to the special issue Breaking Boundaries in Breast Cancer Care: Emerging Controversies and Innovation in Surgical and Medical Approaches

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280 12 0

Open Access Review

Post-CDK4/6 inhibitor therapy in HR+/HER2– advanced breast cancer: expanding options and persisting uncertainties

Anne-Murielle Hollinger, Ruben Bill

Published: September 11, 2026 Explor Target Antitumor Ther. 2026;7:1002400

DOI: https://doi.org/10.37349/etat.2026.1002400

This article belongs to the special issue Breaking Boundaries in Breast Cancer Care: Emerging Controversies and Innovation in Surgical and Medical Approaches

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712 27 0

Open Access Perspective

Mitochondrial checkpoint for interferon responses in macrophages

Andreas O. Mieland, Oliver H. Krämer

Published: August 19, 2026 Explor Target Antitumor Ther. 2026;7:1002399

DOI: https://doi.org/10.37349/etat.2026.1002399

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592 27 0

Open Access Review

Response-adaptive breast cancer care in the grey zones: integrating ER and HER2 targeted PET, FDG PET/CT under immunotherapy, and ctDNA kinetics

Jovana Zivanovic, Jules Zhang-Yin

Published: August 16, 2026 Explor Target Antitumor Ther. 2026;7:1002398

DOI: https://doi.org/10.37349/etat.2026.1002398

This article belongs to the special issue Breaking Boundaries in Breast Cancer Care: Emerging Controversies and Innovation in Surgical and Medical Approaches

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866 30 0

Open Access Review

Bioethical challenges in the implementation of targeted anti-tumor therapies in low-resource settings: a perspective from Latin America

Alcides Chaux

Published: August 10, 2026 Explor Target Antitumor Ther. 2026;7:1002397

DOI: https://doi.org/10.37349/etat.2026.1002397

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681 29 1

Open Access Review

Precision oncology in the treatment of patients with bone sarcomas: an up-to-date narrative review

Sude Yarar, Panagiotis Tsagkozis

Published: August 09, 2026 Explor Target Antitumor Ther. 2026;7:1002396

DOI: https://doi.org/10.37349/etat.2026.1002396

This article belongs to the special issue Precision Oncology: Molecular Classification, Efficacy Prediction, and Treatment Decision-Making

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905 21 0

Open Access Original Article

Safety and efficacy of delivering systemic treatments concomitantly with whole-brain radiotherapy: a prospective, observational, single-institution study

Maria Protopapa ... Anna Zygogianni

Published: August 07, 2026 Explor Target Antitumor Ther. 2026;7:1002395

DOI: https://doi.org/10.37349/etat.2026.1002395

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597 12 0

Open Access Review

Liquid biopsy in breast cancer: current biomarker platforms and clinical applications

Pritam Saha Podder ... Stefano Cinti

Published: August 05, 2026 Explor Target Antitumor Ther. 2026;7:1002394

DOI: https://doi.org/10.37349/etat.2026.1002394

This article belongs to the special issue Breaking Boundaries in Breast Cancer Care: Emerging Controversies and Innovation in Surgical and Medical Approaches

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1182 26 0

Open Access Original Article

Dendritic cell-based immunotherapy modulates the systemic inflammatory profile in a 4T1 breast cancer model

Tauana Christina Dias ... Márcia Antoniazi Michelin

Published: August 05, 2026 Explor Target Antitumor Ther. 2026;7:1002393

DOI: https://doi.org/10.37349/etat.2026.1002393

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744 16 0

Open Access Original Article

Consensus statements on the definition, diagnosis, and management of oligoprogressive disease: results of an expert survey of Kazakhstan Cancer Society

Dilyara Kaidarova ... Timur Mitin

Published: August 05, 2026 Explor Target Antitumor Ther. 2026;7:1002392

DOI: https://doi.org/10.37349/etat.2026.1002392

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5710 25 0

Open Access Original Article

Transcriptional modulation of the PI3K/AKT/mTOR signaling pathway mediated by HPV16 E5, E6, and E7 oncogene expression in breast cancer

Beatriz Eda de Oliveira Isídio ... Antonio Carlos de Freitas

Published: August 04, 2026 Explor Target Antitumor Ther. 2026;7:1002391

DOI: https://doi.org/10.37349/etat.2026.1002391

This article belongs to the special issue Breaking Boundaries in Breast Cancer Care: Emerging Controversies and Innovation in Surgical and Medical Approaches

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987 13 1

Open Access Review

Targeting tumor transition windows

Ola A Al-Ewaidat, Moawiah M Naffaa

Published: July 30, 2026 Explor Target Antitumor Ther. 2026;7:1002390

DOI: https://doi.org/10.37349/etat.2026.1002390

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2404 19 1

Open Access Original Article

Comparative outcomes of open, laparoscopic, and robot-assisted radical cystectomy using IPTW-adjusted trifecta and pentafecta metrics

Nobutaka Nishimura ... Nobumichi Tanaka

Published: July 29, 2026 Explor Target Antitumor Ther. 2026;7:1002389

DOI: https://doi.org/10.37349/etat.2026.1002389

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691 7 0

Open Access Original Article

Distinct transcriptomic features of tumor and stromal cells in direct contact in luminal and triple-negative breast cancers

Anna Yu. Kalinchuk ... Liubov A. Tashireva

Published: July 29, 2026 Explor Target Antitumor Ther. 2026;7:1002388

DOI: https://doi.org/10.37349/etat.2026.1002388

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1323 12 0

Open Access Original Article

Paclitaxel and carboplatin after disease progression on immune checkpoint inhibitor for patients with metastatic urothelial carcinoma

Albert Jang ... Lance C. Pagliaro

Published: July 29, 2026 Explor Target Antitumor Ther. 2026;7:1002387

DOI: https://doi.org/10.37349/etat.2026.1002387

This article belongs to the special issue Emerging Innovation in Surgical and Medical Approaches on the Horizon for Urogenital Malignancies

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928 16 0

Open Access Original Article

Transurethral laser ablation using 980-nm diode laser for recurrent non-muscle invasive bladder cancer

Hideo Fukuhara ... Keiji Inoue

Published: July 28, 2026 Explor Target Antitumor Ther. 2026;7:1002386

DOI: https://doi.org/10.37349/etat.2026.1002386

This article belongs to the special issue Emerging Innovation in Surgical and Medical Approaches on the Horizon for Urogenital Malignancies

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812 15 0

Open Access Short Communication

FGFR3 gene alteration and protein expression in upper urinary tract carcinoma: unsuitability of ureteroscopic biopsy specimens for FGFR3 RNA testing

Makito Miyake ... Kiyohide Fujimoto

Published: July 28, 2026 Explor Target Antitumor Ther. 2026;7:1002385

DOI: https://doi.org/10.37349/etat.2026.1002385

This article belongs to the special issue Emerging Innovation in Surgical and Medical Approaches on the Horizon for Urogenital Malignancies

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890 12 0

Open Access Review

Can we now save the neck of OSCC T1–T2 patients? A narrative review of whether experimental techniques are on the way to clinical application

Vincenzo Cuccurullo ... Giuseppe Lucio Cascini

Published: July 23, 2026 Explor Target Antitumor Ther. 2026;7:1002384

DOI: https://doi.org/10.37349/etat.2026.1002384

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909 20 0

Open Access Review

Reactive oxygen species (ROS) in cancer: from redox signaling and metabolic plasticity to therapeutic vulnerabilities

Taslim Uddin ... Shubhro Saha

Published: July 23, 2026 Explor Target Antitumor Ther. 2026;7:1002383

DOI: https://doi.org/10.37349/etat.2026.1002383

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