• Special Issue Topic

    Emerging Concepts in Subarachnoid Hemorrhage

    Submission Deadline: May 01, 2022

    Guest Editor

    Dr. Brandon Lucke-Wold E-Mail

    Department of Neurosurgery, University of Florida, Gainesville, FL 32608, USA.

    Research Keywords: subarachnoid hemorrhage; neurosurgery; neurotrauma; simulation

    About the Special Issue

    Subarachnoid hemorrhage (SAH) continues to present serious challenges for clinicians and researchers. High morbidity and mortality exist with 1/3 of patients never making it to the hospital. As endovascular techniques have emerged, safe and more efficient aneurysm securement options are now available. The shift has become a focus on secondary mechanisms that occur after the initial hemorrhage. It is well known that vasospasm and delayed cerebral ischemia develop days to weeks after injury. What is still poorly understood are the contributory mechanisms leading to these downstream cascades. This has limited the development of effective therapeutics. This special issue will focus on those emerging topics. We are interested in both clinical and pre-clinical studies as well as focused reviews. Topics of particular importance include the role of microglia, the neuroinflammatory surge, and how the glymphatic system may contribute. Authors are encouraged to provide novel and innovative research to address such topics and help propel the field forward. This forum offers a unique advantage for sharing ideas and encouraging collaborative efforts.

    Keywords: subarachnoid hemorrhage; neuroinflammation; vasospasm; delayed cerebral ischemia; glymphatics

    Call for Papers

    Published Articles

    Open Access
    The glymphatic system and subarachnoid hemorrhage: disruption and recovery
    The glymphatic system, or glial-lymphatic system, is a waste clearance system composed of perivascular channels formed by astrocytes that mediate the clearance of proteins and metabolites from the b [...] Read more.
    Stephan Quintin ... Brandon Lucke-Wold
    Published: June 21, 2022 Explor Neuroprot Ther. 2022;2:118–130
    DOI: https://doi.org/10.37349/ent.2022.00023
    Times Cited: 0
    Open Access
    Subarachnoid hemorrhage: management considerations for COVID-19
    Subarachnoid hemorrhage (SAH) has deleterious outcomes for patients, and during the hospital stay, patients are susceptible to vasospasm and delayed cerebral ischemia. Coronavirus disease 2019 (COVI [...] Read more.
    Eric J. Panther, Brandon Lucke-Wold
    Published: March 02, 2022 Explor Neuroprot Ther. 2022;2:65–73
    DOI: https://doi.org/10.37349/ent.2022.00018
    Times Cited: 0