• 9 results in Exploration of Targeted Anti-tumor Therapy
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    Clinical applications of liquid biopsy in HPV-negative and HPV-positive head and neck squamous cell carcinoma: advances and challenges
    Head and neck squamous cell carcinomas (HNSCCs) represent the most common epithelial tumors that arise from mucosa of the oral cavity, pharynx, and larynx. The development of HNSCCs is usually assoc [...] Read more.
    Mariana Chantre-Justino ... Lucas Delmonico
    Published: August 31, 2022 Explor Target Antitumor Ther. 2022;3:533–552
    DOI: https://doi.org/10.37349/etat.2022.00099
    This article belongs to the special issue The Implementation of Liquid Biopsy in Clinical Practice for Different Solid Tumor
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    miRNA therapeutics in precision oncology: a natural premium to nurture
    The dynamic spectrum of microRNA (miRNA) has grown significantly over the years with its identification and exploration in cancer therapeutics and is currently identified as an important resource fo [...] Read more.
    Chakresh Kumar Jain ... R Suresh Kumar
    Published: August 31, 2022 Explor Target Antitumor Ther. 2022;3:511–532
    DOI: https://doi.org/10.37349/etat.2022.00098
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    Review
    Myeloid-derived suppressor cells in colorectal cancer: prognostic biomarkers and therapeutic targets
    Myeloid-derived suppressor cells (MDSCs) are a group of immature myeloid cells, which are expanded in most cancer patients. MDSCs suppress host immune responses, leading to cancer growth and progres [...] Read more.
    Mohammad A. Al-Mterin, Eyad Elkord
    Published: August 31, 2022 Explor Target Antitumor Ther. 2022;3:497–510
    DOI: https://doi.org/10.37349/etat.2022.00097
    This article belongs to the special issue Cancer Immunotherapy and Tumor Microenvironment
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    Review
    Endocrine therapy resistance: what we know and future directions
    Endocrine resistance is a major hurdle in the treatment of estrogen receptor (ER)-positive breast cancer. When abnormally regulated, molecular signals responsible for cellular proliferation, as well [...] Read more.
    David Musheyev, Anya Alayev
    Published: August 31, 2022 Explor Target Antitumor Ther. 2022;3:480–496
    DOI: https://doi.org/10.37349/etat.2022.00096
    This article belongs to the special issue Endocrine Resistant Breast Cancer
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    Review
    A personalized molecular approach in multiple myeloma: the possible use of RAF/RAS/MEK/ERK and BCL-2 inhibitors
    Multiple myeloma (MM) is a blood cancer that derives from plasma cells (PCs), which will accumulate in the bone marrow (BM). Over time, several drugs have been developed to treat this disease that i [...] Read more.
    Vincenzo Raimondi ... Nicola Giuliani
    Published: August 31, 2022 Explor Target Antitumor Ther. 2022;3:463–479
    DOI: https://doi.org/10.37349/etat.2022.00095
    This article belongs to the special issue Off-label drugs and -omics data in cancer treatment
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    Review
    Roles of calcium signaling in cancer metastasis to bone
    Bone metastasis is a frequent complication for cancers and an important reason for the mortality in cancer patients. After surviving in bone, cancer cells can cause severe pain, life-threatening hyp [...] Read more.
    Tianying Xie ... Jianru Xiao
    Published: August 31, 2022 Explor Target Antitumor Ther. 2022;3:445–462
    DOI: https://doi.org/10.37349/etat.2022.00094
    This article belongs to the special issue Calcium Signaling Apparatus in Cancers
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    Open Access
    Review
    Applications and challenges of biomaterial mediated mRNA delivery
    With the rapid development of gene therapy technology and the outbreak of coronavirus disease 2019 (COVID-19), messenger RNA (mRNA) therapeutics have attracted more and more attention, and the COVID [...] Read more.
    Huapan Fang, Qian Chen
    Published: August 31, 2022 Explor Target Antitumor Ther. 2022;3:428–444
    DOI: https://doi.org/10.37349/etat.2022.00093
    This article belongs to the special issue Gene Delivery Approach to Fight Cancer
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    Perspective
    Anticancer action of plant products: changing stereotyped attitudes
    Compared to humans, plants can synthesize an extremely diverse array of chemical compounds, including phenolic acids, flavonoids, stilbenes, lignans, terpenoids, alkaloids, and many other types of s [...] Read more.
    Katrin Sak
    Published: August 15, 2022 Explor Target Antitumor Ther. 2022;3:423–427
    DOI: https://doi.org/10.37349/etat.2022.00092
    This article belongs to the special issue Plant Extracts as an Infinite Resource for New Anticancer Agents
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    Original Article
    Consequences of the impact of COVID-19 pandemic on breast cancer at a single Italian institution
    Aim: To evaluate the local impact of the coronavirus disease 2019 (COVID-19) pandemic on breast cancer (BC) care, with particular attention to the economical and psychological consequences of the [...] Read more.
    Daniele Ugo Tari ... Fabio Pinto
    Published: July 29, 2022 Explor Target Antitumor Ther. 2022;3:414–422
    DOI: https://doi.org/10.37349/etat.2022.00091
    This article belongs to the special issue Covid-19 and Cancer
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