• Special Issue Topic

    Atopic Dermatitis – Pathology and Treatment modalities

    Submission Deadline: September 30, 2024

    Guest Editor

    Prof. Somasundaram Arumugam E-Mail

    Assistant Professor, Department of Pharmacology & Toxicology, National Institute of Pharmaceutical Education and Research (NIPER) - Kolkata, India

    Research Keywords: Inflammation, inflammatory disorders, immune response, natural products, pharmacology, drug screening, toxicology


    About the Special Issue

    Atopic dermatitis (AD), also known as eczema, is a chronic inflammatory skin condition that often appears as red, itchy rashes. Its exact cause isn't fully understood, but it's believed to involve a combination of genetic, environmental, and immune system factors. People with AD often have a compromised skin barrier, which allows moisture to escape and irritants or allergens to enter, leading to dryness and inflammation. Similarly, an overactive immune response plays a role in the inflammation and itching associated with AD. Certain immune cells release chemicals that cause skin irritation and itching. In addition, mutations in genes responsible for maintaining the skin barrier function and regulating the immune system contribute to its development.

    This special issue will focus on recent advances in atopic dermatitis research, its pathophysiology, preclinical and clinical studies for drug discovery, including complementary approaches for its treatment. Contributions are welcome from both clinicians as well as basic researchers involved in all aspects of AD research and healthcare. Biomarker and disease target identification for AD is also solicited for this special issue.

    Keywords: Atopic dermatitis, allergy, hypersensitivity, natural products, animal models, mast cells, inflammation

    Call for Papers

    Published Articles

    Open Access
    Original Article
    Atopic dermatitis in adults: prevalence, clinical pattern, and contact sensitization
    Aim: Few reports on atopic dermatitis (AD) in adults from Africa exist in the literature. AD in adults can occur as childhood-onset, in which AD begins in childhood and continues till adulthood,  [...] Read more.
    Perpetua U. Ibekwe ... Bob A. Ukonu
    Published: September 06, 2024 Explor Asthma Allergy. 2024;2:450–460
    DOI: https://doi.org/10.37349/eaa.2024.00057
    View:702
    Download:29
    Times Cited: 0
    Open Access
    Review
    Current approach to moisturizer and emollient utilization in atopic dermatitis: a review
    Atopic dermatitis (AD) is a chronic inflammatory skin disease that primarily affects the barrier function of the skin in patients. The condition has been documented to cause xerosis in patients from [...] Read more.
    Serap Maden
    Published: August 27, 2024 Explor Asthma Allergy. 2024;2:441–449
    DOI: https://doi.org/10.37349/eaa.2024.00056
    View:805
    Download:56
    Times Cited: 0
    Open Access
    Review
    Revisiting immunotherapeutic strategies for the management of atopic dermatitis
    Atopic dermatitis (AD) represents the most common inflammatory skin disease with a highly intricated immune fingerprint. Until recently, AD management mostly relied on topical corticosteroids, calci [...] Read more.
    Gael Tchokomeni Siwe ... Stefan Barth
    Published: August 09, 2024 Explor Asthma Allergy. 2024;2:373–398
    DOI: https://doi.org/10.37349/eaa.2024.00052
    View:743
    Download:30
    Times Cited: 0