• Special Issue Topic

    Ketogenic Diet as Medical Nutrition Therapy

    Submission Deadline: December 07, 2024

    Guest Editors

    Luca Rastrelli E-Mail

    Department of Pharmacy, University of Salerno,Salerno, Italy

    Research Keywords: ketogenic diet; phytotherapy; food supplements; analytical techniques; metabolomic

    Giuseppe Castaldo E-Mail

    NutriKeto_LAB Unisa−“San Giuseppe Moscati” National Hospital (AORN), Avellino, Italy

    Research Keywords: ketogenic diet; insulin-resistance inflammation; obesity; microbiota

    About the Special Issue

    The ketogenic diet is a nutritional regimen characterized by a reduction in carbohydrates and a relative increase in protein and fat. At a biochemical level, the ketogenic diet induces a switch to ketone metabolism, causing a reduction in blood glucose and an increase in blood ketones and mitochondrial function, from this point of view is able to counteract insulin resistance and fight generalized or localized adiposity. Recent scientific studies have shown the therapeutic potential of ketogenic diets in many diseases, such as diabetes, polycystic ovary syndrome, acne, neurological diseases, cancer, and the amelioration of respiratory and cardiovascular disease risk factors. Moreover, the ketogenic diet has been identified as an effective remedy for obesity and psoriasis, with a significant reduction in inflammatory components that are possibly localized in visceral adipose tissue.

    This special issue aims to increase and potentiate some results and to open new challenges for clinical application of the KD in the treatment of pathologies linked to inflammation. The encouraging results as nutritional therapy and the new insights about the mechanism of action connected to intestinal microbiota health, make it possible to suggest KD as an alternative therapy in complex diseases.

    In this very wide context we encourage the submission of original research paper, reviews, and clinical and laboratory studies, that explore all these aspects. 

    Keywords: ketogenic diet; insulin-resistance inflammation; obesity; microbiota

    Call for Papers

    Published Articles

    Open Access
    Evaluation of the most common parameters used to describe cardiovascular risk and the influence of ketogenic and Mediterranean diet
    Cardiovascular disease (CVD) stands as the leading global cause of mortality, underscoring the critical need for practical tools to assess CVD risk at an early stage. An accessible approach involves [...] Read more.
    Leo Karl Hanke ... Paola Molettieri
    Published: December 28, 2023 Explor Foods Foodomics. 2023;1:244–257
    DOI: https://doi.org/10.37349/eff.2023.00019
    Times Cited: 0
    Open Access
    Male obesity secondary hypogonadism: effectiveness of ketogenic diet on testicular function
    Epidemiological studies have reported an association between obesity/metabolic syndrome (MetS) and male reproductive disorders. Endocrine dysfunctions, direct testicular damage, chronic low-grade in [...] Read more.
    Giulia Izzo ... Mario Vitale
    Published: October 29, 2023 Explor Foods Foodomics. 2023;1:178–191
    DOI: https://doi.org/10.37349/eff.2023.00014
    Times Cited: 0