• 7 results in Exploration of Targeted Anti-tumor Therapy
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    Clinical aspect, pathogenesis and therapy options of alopecia induced by hormonal therapy for breast cancer
    Adjuvant hormonal therapy is one of the most important treatments of hormone-receptor-positive breast cancer and includes selective estrogen receptor modulators, aromatase inhibitors, and luteinizin [...] Read more.
    Alfredo Rossi ... Marta Carlesimo
    Published: October 31, 2021 Explor Target Antitumor Ther. 2021;2:490-495
    DOI: https://doi.org/10.37349/etat.2021.00059
    This article belongs to the special issue Endocrine Resistant Breast Cancer
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    Original Article
    Performing oncological procedures during COVID-19 outbreak: a picture from an Italian cancer center
    Aim: Since SARS-CoV-2 infection rapidly spread around the world, Italy has quickly become one of the most affected countries. Healthcare systems introduced strict infection control measures to ensu [...] Read more.
    Maristella Bungaro ... Silvia Novello
    Published: October 31, 2021 Explor Target Antitumor Ther. 2021;2:481-489
    DOI: https://doi.org/10.37349/etat.2021.00058
    This article belongs to the special issue COVID-19 and Cancer
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    Review
    Targeted therapy of multiple myeloma
    Multiple myeloma (MM) is a malignant proliferative disease of monoclonal plasma cells (PCs) and is characterized by uncontrolled proliferation of PCs and excessive production of specific types of im [...] Read more.
    Shan Zhou, Renxi Wang
    Published: October 31, 2021 Explor Target Antitumor Ther. 2021;2:465-480
    DOI: https://doi.org/10.37349/etat.2021.00057
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    Review
    A review of molecularly targeted therapy in biliary tract carcinoma: what is the next step?
    Patients with unresectable biliary tract carcinomas (BTCs) have a poor prognosis with a median overall survival of fewer than 12 months following systemic chemotherapy. In recent years, the identifi [...] Read more.
    Giacomo Aimar ... Massimo Di Maio
    Published: October 31, 2021 Explor Target Antitumor Ther. 2021;2:448-464
    DOI: https://doi.org/10.37349/etat.2021.00056
    This article belongs to the special issue Precision Medicine for Cholangiocarcinoma
    Open Access
    Review
    Targeting protein kinase CK2 in the treatment of cholangiocarcinoma
    Cholangiocarcinoma (CCA) is a disease with a very poor prognosis and limited treatment options. Although targeted therapies directed towards specific mutations found in CCA are becoming available an [...] Read more.
    Padma-Sheela Jayaraman, Kevin Gaston
    Published: October 31, 2021 Explor Target Antitumor Ther. 2021;2:434-447
    DOI: https://doi.org/10.37349/etat.2021.00055
    This article belongs to the special issue Precision Medicine for Cholangiocarcinoma
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    Review
    Current options and future directions of systemic therapy for advanced biliary tract cancer
    Biliary tract cancers (BTCs) are aggressive tumors arising from different portions of the biliary tree and classified according to the anatomical location in intrahepatic (i) cholangiocarcinoma (CCA [...] Read more.
    Maria Giuseppina Prete ... Lorenza Rimassa
    Published: October 31, 2021 Explor Target Antitumor Ther. 2021;2:416-433
    DOI: https://doi.org/10.37349/etat.2021.00054
    This article belongs to the special issue Precision Medicine for Cholangiocarcinoma
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    Review
    A novel strategy for treating cancer: understanding the role of Ca2+ signaling from nociceptive TRP channels in regulating cancer progression
    Cancer is an aging-associated disease and caused by genomic instability that is driven by the accumulation of mutations and epimutations in the aging process. Although Ca2+ signaling, re [...] Read more.
    Wen-Li Hsu ... Etsuro Ito
    Published: October 31, 2021 Explor Target Antitumor Ther. 2021;2:401-415
    DOI: https://doi.org/10.37349/etat.2021.00053
    This article belongs to the special issue Calcium Signaling Apparatus in Cancers
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