• 5 results in Exploration of Targeted Anti-tumor Therapy
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    Review
    Role of estrogen receptor coregulators in endocrine resistant breast cancer
    Breast cancer (BC) is the most ubiquitous cancer in women. Approximately 70–80% of BC diagnoses are positive for estrogen receptor (ER) alpha (ERα). The steroid ho...
    Kristin A. Altwegg, Ratna K. Vadlamudi
    Published: August 30, 2021 Explor Target Antitumor Ther. 2021;2:385-400
    DOI: https://doi.org/10.37349/etat.2021.00052
    This article belongs to the special issue Endocrine Resistant Breast Cancer
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    Review
    Does the gut microbiome environment influence response to systemic breast cancer treatment?
    The gut microbiome is a novel player in the pathogenesis and treatment of breast cancer. The term “microbiome” is used to describe the diverse community of micro-organisms exis...
    Eilidh Bruce ... Beatrix Elsberger
    Published: August 30, 2021 Explor Target Antitumor Ther. 2021;2:374-384
    DOI: https://doi.org/10.37349/etat.2021.00051
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    Review
    The evolving role and utility of off-label drug use in multiple myeloma
    The treatment landscape for multiple myeloma (MM) has dramatically changed over the last three decades, moving from no US Food and Drug Administration approvals and two active drug classes to over 1...
    James H Stoeckle ... Gareth J Morgan
    Published: August 30, 2021 Explor Target Antitumor Ther. 2021;2:355-373
    DOI: https://doi.org/10.37349/etat.2021.00050
    This article belongs to the special issue Off-Label Drugs and -Omics Data in Cancer Treatment
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    Review
    The promising potential of piperlongumine as an emerging therapeutics for cancer
    In spite of the immense advancement in the diagnostic and treatment modalities, cancer continues to be one of the leading causes of mortality across the globe, responsible for the death of around 10...
    Dey Parama ... Ajaikumar B. Kunnumakkara
    Published: August 30, 2021 Explor Target Antitumor Ther. 2021;2:323-354
    DOI: https://doi.org/10.37349/etat.2021.00049
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    Original Article
    The effect of iron on the expression levels of calcium related gene in cisplatin resistant epithelial ovarian cancer cells
    Aim: Anticancer drugs (chemotherapeutics) used in cancer treatment (chemotherapy) lead to drug resistance. This study was conducted to investigate the possible effect of iron on calcium homeostasis...
    Bahire Kucukkaya ... Leman Yalcintepe
    Published: August 30, 2021 Explor Target Antitumor Ther. 2021;2:309-322
    DOI: https://doi.org/10.37349/etat.2021.00048
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