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    3articles Vol.2(2024)
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    Open Access
    Original Article
    Interaction of norsecurinine-type monomeric and dimeric alkaloids with α-tubulin: a molecular docking study
    Aim: New microtubule-targeting agents are needed to improve cancer treatment. The recent characterization of the anticancer alkaloid securinine as a tubulin-binding agent prompted us to explore t [...] Read more.
    Gérard Vergoten, Christian Bailly
    Published: May 21, 2024 Explor Drug Sci. 2024;2:277–291
    DOI: https://doi.org/10.37349/eds.2024.00047
    Times Cited: 0
    Open Access
    Mini Review
    Pain management for the neurosurgical patient in spinal procedures: overview of historic and new modalities
    The potent pain-relieving properties of opioids come at a steep price. Their addictive nature and side effects raise critical concerns in managing pain after surgical spine procedures. Postoperative [...] Read more.
    Ashley M. Carter ... Brandon Lucke-Wold
    Published: May 21, 2024 Explor Drug Sci. 2024;2:268–276
    DOI: https://doi.org/10.37349/eds.2024.00046
    Times Cited: 0
    Open Access
    Original Article
    Stryphnodendron adstringens have a modulatory effect on inflammatory cytokines markers of in vitro activated macrophages
    Aim: The purpose of this study is to conduct a comprehensive investigation into the modulatory effects of Stryphnodendron adstringens (Mart.; S. adstringens), a Brazilian wound-healing plant, on  [...] Read more.
    Ivana Beatrice Mânica da Cruz ... Fernanda Barbisan
    Published: May 11, 2024 Explor Drug Sci. 2024;2:254–267
    DOI: https://doi.org/10.37349/eds.2024.00045
    Times Cited: 0