Exploration of Drug Science

Table 7. Toxicity profile of EUB0000226b.

No.	Target	Classification	Prediction	Probability
1	Hepatotoxicity	Organ toxicity	Inactive	0.50
2	Nephrotoxicity	Organ toxicity	Inactive	0.63
3	Respiratory toxicity	Organ toxicity	Active	0.82
4	Cardiotoxicity	Organ toxicity	Inactive	0.89
5	Immunotoxicity	Toxicity endpoints	Inactive	0.72
6	Carcinogenicity	Toxicity endpoints	Inactive	0.53
7	Mutagenicity	Toxicity endpoints	Inactive	0.62
8	Cytotoxicity	Toxicity endpoints	Inactive	0.73
9	Phosphoprotein (tumour suppressor) p53	Tox-21-stress response pathways	Inactive	0.78
10	GABA receptor (GABAR)	Molecular initiating events	Inactive	0.77
11	Voltage-gated sodium channel (VGSC)	Molecular initiating events	Inactive	0.64

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Declarations

Author contributions

AOM: Conceptualization, Data curation, Formal analysis, Methodology, Resources, Investigation, Writing—original draft. AJA: Formal analysis, Methodology, Investigation, Writing—review & editing. MEA: Resources, Methodology, Investigation, Writing—review & editing. SOI: Visualization, Resources, Writing—review & editing. YOA: Software, Writing—review & editing. All authors read and approved the submitted version.

Conflicts of interest

Authors declare no conflict of interest.

Ethical approval

Not applicable.

Consent to participate

Not applicable.

Consent to publication

Not applicable.

Availability of data and materials

Data generated from this study are available from the corresponding author upon reasonable request.

Funding

This research did not receive any specific grant from funding agencies in the public, commercial, or not-for-profit sectors.

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