Study type distribution.
| Study type | Number of studies (n) | Percentage of studies (%) |
|---|---|---|
| In vivo | 66 | 37.3% |
| In vitro | 92 | 52.0% |
| In silico | 15 | 8.5% |
| Other hybrid methods: human trial, computational, DIA proteomics, HCS | 4 | 2.3% |
| Total | 177 | 100.1% |
HCS: high-content screening. Due to rounding, the sum of various percentages may not equal 100%.
The supplementary table for this article is available at: https://www.explorationpub.com/uploads/Article/file/1008139_sup_1.xlsx.
This review benefited from insightful feedback provided by Dr. Kusum Dua, Prof. Asma Wasim, and Timothy G. Leaks (MSc), at the Department of Health Science at the University of the People, whose critical comments helped improve the clarity and depth of our analysis.
CPI: Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Project administration, Resources, Software, Supervision, Validation, Visualization, Writing—original draft, Writing—review & editing. ESMT: Conceptualization, Investigation, Methodology, Project administration, Resources, Software, Supervision, Validation, Visualization, Writing—original draft, Writing—review & editing. EFE: Conceptualization, Investigation, Validation, Resources, Software, Writing—original draft. MRI: Conceptualization, Investigation, Resources, Software, Validation, Writing—original draft. All authors read and approved the submitted version.
The authors declare that they have no conflicts of interest.
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The primary data for this review were sourced online from databases listed in the methods. Referenced articles are accessible on PubMed, Scopus, Google Scholar, and Europe PMC. Additional supporting data are available from the corresponding author upon request.
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