• 8 results in Exploration of Targeted Anti-tumor Therapy
    Sort by
    Latest
    Open Access
    Original Article
    Combination of thermal ablation by focused ultrasound, pFAR4-IL-12 transfection and lipidic adjuvant provide a distal immune response
    Aim: Gene-based immunotherapy against cancer is limited by low gene transfer efficiency. In the literature, interleukin-12 (IL-12) encoding plasmid associated with sonoporation has been shown to en [...] Read more.
    Hai Doan Do ... Nathalie Mignet
    Published: June 29, 2022 Explor Target Antitumor Ther. 2022;3:398–413
    DOI: https://doi.org/10.37349/etat.2022.00090
    This article belongs to the special issue Gene Delivery Approach to Fight Cancer
    View:2238
    Download:93
    Times Cited: 0
    Open Access
    Case Report
    Advanced metastatic pancreatic neuroendocrine tumor treated successfully with peptide receptor radionuclide therapy: a case report
    Neuroendocrine tumor (NET) is a rare tumor that has been observed in different sites such as lungs and throughout the gastrointestinal tract. Clinical features are usually non-specific and vary cons [...] Read more.
    Amit Kumar ... Rohit Kumar
    Published: June 29, 2022 Explor Target Antitumor Ther. 2022;3:392–397
    DOI: https://doi.org/10.37349/etat.2022.00089
    View:1133
    Download:71
    Times Cited: 0
    Open Access
    Original Article
    Allosteric cross-talk between the hydrophobic cleft and the BH4 domain of Bcl-2 in control of inositol 1,4,5-trisphosphate receptor activity
    Aim: Inositol 1,4,5-trisphosphate receptor (IP3R) is a ubiquitous calcium (Ca2+) channel involved in the regulation of cellular fate and motility. Its modulation by anti-apoptotic prote [...] Read more.
    George Shapovalov ... Natalia Prevarskaya
    Published: June 28, 2022 Explor Target Antitumor Ther. 2022;3:375–391
    DOI: https://doi.org/10.37349/etat.2022.00088
    This article belongs to the special issue The Role of Bcl-2 Family Proteins in Cancer Progression and Their Relevance to Cancer Therapy
    View:1558
    Download:53
    Open Access
    Review
    Liquid biopsy in biliary tract cancer from blood and bile samples: current knowledge and future perspectives
    Biliary tract cancer (BTC) is an aggressive tumor characterized by a poor prognosis. In the latest years, targetable genetic alterations have been discovered in BTC patients, leading to the approval [...] Read more.
    Gianluca Arrichiello ... Emilio Francesco Giunta
    Published: June 22, 2022 Explor Target Antitumor Ther. 2022;3:362–374
    DOI: https://doi.org/10.37349/etat.2022.00087
    This article belongs to the special issue The Implementation of Liquid Biopsy in Clinical Practice for Different Solid Tumor
    View:1618
    Download:47
    Open Access
    Review
    Exploring new pathways in endocrine-resistant breast cancer
    The most common breast cancer (BC) subtypes are hormone-dependent, being either estrogen receptor-positive (ER+), progesterone receptor-positive (PR+), or both, and altogether comprise the luminal subtype. Th [...] Read more.
    Inês Soares de Pinho ... Luís Costa
    Published: June 20, 2022 Explor Target Antitumor Ther. 2022;3:337–361
    DOI: https://doi.org/10.37349/etat.2022.00086
    This article belongs to the special issue Endocrine Resistant Breast Cancer
    View:1740
    Download:44
    Open Access
    Systematic Review
    Management of lung cancer patients during COVID-19 pandemic: dos, don’ts and don’t knows
    Aim: During the coronavirus disease 2019 (COVID-19) pandemic two needs have overlapped: on one hand continuing to provide the best care for patients with lung cancer and preventing the spread of the [...] Read more.
    Mariangela Torniai ... Rossana Berardi
    Published: June 10, 2022 Explor Target Antitumor Ther. 2022;3:321–336
    DOI: https://doi.org/10.37349/etat.2022.00085
    This article belongs to the special issue COVID-19 and Cancer
    View:1185
    Download:36
    Times Cited: 0
    Open Access
    Review
    In vitro breast cancer models for studying mechanisms of resistance to endocrine therapy
    The development of endocrine resistance is a common reason for the failure of endocrine therapies in hormone receptor-positive breast cancer. This review provides an overview of the different types  [...] Read more.
    Gary J. Cheng ... Dean C. Singleton
    Published: June 01, 2022 Explor Target Antitumor Ther. 2022;3:297–320
    DOI: https://doi.org/10.37349/etat.2022.00084
    This article belongs to the special issue Endocrine Resistant Breast Cancer
    View:1992
    Download:70
    Open Access
    Review
    Myeloid cell leukemia-1: a formidable barrier to anticancer therapeutics and the quest of targeting it
    The antiapoptotic B cell lymphoma-2 (Bcl-2) family members are apical regulators of the intrinsic pathway of apoptosis that orchestrate mitochondrial outer membrane permeabilization (MOMP) through i [...] Read more.
    Prasad Sulkshane, Tanuja Teni
    Published: May 24, 2022 Explor Target Antitumor Ther. 2022;3:278–296
    DOI: https://doi.org/10.37349/etat.2022.00083
    This article belongs to the special issue The Role of Bcl-2 Family Proteins in Cancer Progression and Their Relevance to Cancer Therapy
    View:1834
    Download:43