• 4 results in Exploration of Digestive Diseases
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    Original Article
    Probiotic human alcohol dehydrogenase-4 expressing bacteria protects from diet-induced obesity and metabolic impairment: a new concept of disease prevention
    Aim: Probiotic bacteria consumption for improving human health and for disease prevention is still controversial. There is a need to develop functional probiotic bacteria with proven efficacy for [...] Read more.
    Rajnish Prakash Singh ... Zvi Hayouka
    Published: October 31, 2022 Explor Dig Dis. 2022;1:118–136
    DOI: https://doi.org/10.37349/edd.2022.00009
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    Review
    Etiopathogenesis and pathophysiology of cholestasis
    Normal hepatobiliary function depends on an adequate bile flow from the liver through the biliary tree to the gallbladder, where bile is stored and concentrated, and from the gallbladder to the duod [...] Read more.
    Maitane Asensio ... Jose J. G. Marin
    Published: October 31, 2022 Explor Dig Dis. 2022;1:97–117
    DOI: https://doi.org/10.37349/edd.2022.00008
    This article belongs to the special issue CHOLESTASIS
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    Review
    Caspase-2 in liver disease and hepatocellular carcinoma
    Caspases are key factors in the regulation of the apoptotic and/or inflammatory responses, both crucial in the pathogenesis of diverse diseases. Caspase-2 is the most evolutionary conserved albeit f [...] Read more.
    Amaya Lopez-Pascual ... Maite G. Fernández-Barrena
    Published: October 31, 2022 Explor Dig Dis. 2022;1:80–96
    DOI: https://doi.org/10.37349/edd.2022.00007
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    Perspective
    The intermicrovillar adhesion complex in gut barrier function and inflammation
    The surface of intestinal epithelial cells is covered by the brush border, which consists of densely packed cellular extrusions called microvilli. Until recently, microvilli have not been known to b [...] Read more.
    Bernadette Mödl ... Robert Eferl
    Published: October 11, 2022 Explor Dig Dis. 2022;1:72–79
    DOI: https://doi.org/10.37349/edd.2022.00006