Characteristics at baseline for patients undergoing physical activity equivalent to ≥ 1,000 MET minutes per week (group 1) or < 1,000 MET minutes per week (group 2).
Data presented as median and interquartile range (IQR) for continuous variables and as number (%) for dichotomous variables. MET: metabolic equivalent of task; BMI: body mass index; NSAID: nonsteroidal anti-inflammatory drugs; CRP: C-reactive protein; LV-GLS: Left ventricular global longitudinal strain; LA-GLS: Left atrial global longitudinal strain; PWV: pulse wave velocity.
Declarations
Author contributions
SM: Writing—original draft, Writing—review & editing, Data curation, Formal analysis. KS and MB: Conceptualization, Investigation, Writing—review & editing, Supervision, Data curation, Formal analysis. DH and AM: Writing—review & editing, Supervision. JGJ, PS, and AV: Writing—review & editing, Formal analysis. CF, BN, CHO, and IEL: Conceptualization, Investigation, Writing—review & editing. All authors read and approved the submitted version.
Conflicts of interest
The authors declare that they have no conflicts of interest.
Ethical approval
The PARA study complied with the Declaration of Helsinki. The original study and the extended follow-up protocol were approved by the Stockholm regional ethics committee (2012/769-32). Clinical trial registration: http://www.isrctn.com. Unique identifier: ISRCTN88886304.
Consent to participate
Informed consent to participate in the study was obtained from all participants.
Consent to publication
Not applicable.
Availability of data and materials
The data that support the findings of this study are not publicly available. The study presented here has been subject to an application to an ethical board and approved for publication related to the specific aim of our research project. With reference to the European General Data Protection Regulation (GDPR), the data are personal data and thereby protected by secrecy.
Funding
PARA 2010 is supported by grants from AFA Insurance (grant number [100172]), the Swedish Research Council, Combine Sweden, the Swedish Rheumatism Foundation, and the KI National Postgraduate School of Health Care Sciences. M.B. is supported by grants from the Swedish Research Council (grant number [2023-02652]), Heart-Lung Foundation (grant number [20240697]), and Region Stockholm (grant number [RS2023-0859]). The funding sources had no role in the design and conduct of the study; collection, management, analysis and interpretation of the data; preparation, review or approval of the manuscript; and decision to submit the manuscript for publication.
Open Exploration maintains a neutral stance on jurisdictional claims in published institutional affiliations and maps. All opinions expressed in this article are the personal views of the author(s) and do not represent the stance of the editorial team or the publisher.
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