From:  How algorithms are transforming the diagnosis of ischemic heart disease—state of the art

 Applications by diagnostic stage.

StageAI toolsMain benefitsReferences
ScreeningAI-ECGEarly detection of latent disease and population-level risk prediction/triage[6, 17]
Anatomical diagnosisAI-CCTA; AI-CMRAccurate plaque quantification and characterization (CCTA); quantitative myocardial tissue characterization, including LGE/T1 mapping (CMR)[7, 10, 11, 21]
Functional assessmentAI-FFR (FFR-CT); AI-perfusion (stress imaging: echocardiography/nuclear)Non-invasive hemodynamic evaluation; lesion-specific ischemia assessment; potential improvement of reader performance in stress imaging[9, 32, 33, 36, 40]
Intervention planningAI-IVUS; AI-OCTProcedure optimization (e.g., stent sizing and landing zone selection), outcome prediction, and intraprocedural decision support[13, 22, 39]
MonitoringIntegrated CDSS (with imaging and ECG data)Personalized risk stratification, longitudinal follow-up, and event prediction with integration of multimodal data into clinical workflows[16, 18, 52]

AI: artificial intelligence; CCTA: coronary computed tomography angiography; CDSS: clinical decision support systems; CMR: cardiovascular magnetic resonance; CT: computed tomography; FFR: fractional flow reserve; FFR-CT: FFR derived from CT; ECG: electrocardiogram; IVUS: intravascular ultrasound; LGE: late gadolinium enhancement; OCT: optical coherence tomography.