The authors declare that there are no conflicts of interest.
Ethical approval
The study was conducted in accordance with institutional guidelines and the principles of the Declaration of Helsinki. A formal ethical approval was not required for this retrospective case report.
Consent to participate
Informed consent to participate in the study was obtained from the patients and/or the next of kin.
Consent to publication
Written informed consent was obtained from the patients and/or the next of kin for publication of this case report and any accompanying images.
Availability of data and materials
The data supporting the findings of this study are available from the corresponding author upon reasonable request.
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References
Costello RA, Leslie SW, Nehring SM. Disseminated Intravascular Coagulation. Treasure Island (FL): StatPearls Publishing; 2024. [PubMed]
Papageorgiou C, Jourdi G, Adjambri E, Walborn A, Patel P, Fareed J, et al. Disseminated Intravascular Coagulation: An Update on Pathogenesis, Diagnosis, and Therapeutic Strategies.Clin Appl Thromb Hemost. 2018;24:8S–28S. [DOI] [PubMed] [PMC]
Cartwright B, Bruce HM, Kershaw G, Cai N, Othman J, Gattas D, et al. Hemostasis, coagulation and thrombin in venoarterial and venovenous extracorporeal membrane oxygenation: the HECTIC study.Sci Rep. 2021;11:7975. [DOI] [PubMed] [PMC]
Yang S, Williams B, Kaczorowski D, Mazzeffi M. Overt Disseminated Intravascular Coagulation with Severe Hypofibrinogenemia During Veno-Venous Extracorporeal Membrane Oxygenation.J ExtraCorpor Technol. 2022;54:148–52. [DOI]
Guglin M, Zucker MJ, Bazan VM, Bozkurt B, El Banayosy A, Estep JD, et al. Venoarterial ECMO for Adults.J Am Coll Cardiol. 2019;73:698–716. [DOI] [PubMed]
Taylor FBJ, Toh CH, Hoots WK, Wada H, Levi M; Scientific Subcommittee on Disseminated Intravascular Coagulation (DIC) of the International Society on Thrombosis and Haemostasis (ISTH). Towards definition, clinical and laboratory criteria, and a scoring system for disseminated intravascular coagulation.Thromb Haemost. 2001;86:1327–30. [DOI] [PubMed]
Fang M, Zha Y, Bao J, Huang R, Han X, Yu C, et al. Evaluation of the revised ISTH overt DIC score (2018) for predicting 90-day mortality in critically ill adult patients undergoing extracorporeal membrane oxygenation.Artif Organs. 2022;46:2442–52. [DOI] [PubMed]
Retter A, Hunt BJ. Consumptive coagulopathy in the ICU.Hematology. 2023;2023:754–60. [DOI] [PubMed] [PMC]
Kim TW, Ko RE, Choi KH, Chung CR, Cho YH, Yang JH. Overt disseminated intravascular coagulation and antithrombin III predict bleeding and in-hospital mortality in patients undergoing extracorporeal membrane oxygenation.Front Med. 2024;11:1335826. [DOI] [PubMed] [PMC]
Popescu NI, Lupu C, Lupu F. Disseminated intravascular coagulation and its immune mechanisms.Blood. 2022;139:1973–86. [DOI] [PubMed] [PMC]
Guo Z, Sun L, Li B, Tian R, Zhang X, Zhang Z, et al. Anticoagulation Management in Severe Coronavirus Disease 2019 Patients on Extracorporeal Membrane Oxygenation.J Cardiothorac Vasc Anesth. 2021;35:389–97. [DOI] [PubMed] [PMC]
Sun Z, Guan X, Pan M, Chen J, Ding L, He T, et al. Direct thrombin inhibiting coating for active coagulant management in extracorporeal circulation.Prog Org Coat. 2024;190:108368. [DOI]
Millar JE, Fanning JP, McDonald CI, McAuley DF, Fraser JF. The inflammatory response to extracorporeal membrane oxygenation (ECMO): a review of the pathophysiology.Crit Care. 2016;20:387. [DOI] [PubMed] [PMC]
Szułdrzyński K, Jankowski M, Fleming M. Systemic Coagulation Derangement as an Early Sign of Oxygenator Failure in Veno-Venous Extracorporeal Membrane Oxygenation (VV ECMO) Without Anticoagulation.Reports. 2024;7:97. [DOI] [PubMed] [PMC]
