From:  Statin adherence patterns among older adults on triple therapy: a real-world study using group-based trajectory model

 Multinomial logistic regression to assess predictors associated with each trajectory (n = 7,847).

VariableRapid decline vs. adherent [OR (95% CI)]p-valueNear-perfect adherent vs. adherent [OR (95% CI)]p-value
Sex (female vs. male)1.354 (1.186–1.546)< 0.0001*1.202 (1.086–1.330)0.0004*
Age (Ref: ≤ 65)
    66–690.792 (0.641–0.978)0.0307*0.910 (0.770–1.077)0.2722
    70–740.661 (0.530–0.823)0.0002*0.908 (0.765–1.077)0.2664
    ≥ 750.760 (0.609–0.950)0.0157*0.941 (0.790–1.120)0.4937
Low-income subsidy (yes vs. no)0.977 (0.854–1.117)0.73491.036 (0.935–1.148)0.4967
≥ 1 prior hospitalization (yes vs. no)1.432 (1.019–2.012)0.0385*0.925 (0.697–1.227)0.5877
Depression (yes vs. no)2.469 (0.545–11.193)0.24113.354 (0.959–11.727)0.0581
CV event (yes vs. no)0.839 (0.570–1.234)0.37230.933 (0.701–1.240)0.6318
CMS risk score0.921 (0.837–1.013)0.08861.016 (0.948–1.088)0.6579
Total other medications0.978 (0.961–0.996)0.016*0.995 (0.981–1.008)0.4174
Regimen complexity1.000 (0.998–1.002)0.98291.000 (0.999–1.001)0.8425
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*indicates statistical significance at p < 0.05. OR: odds ratio; CV: cardiovascular; CMS: Centers for Medicare & Medicaid Services.