We thank Mauricio Rosenbaum and Pablo Chiale, whose work truly inspired this study; the article is dedicated to their memory. We also thank Luigi Tavazzi and Marcello Chimienti for their support and guidance.
Author contributions
MC: Writing—original draft, Writing—review & editing, Conceptualization, Data curation. JASU: Data curation, Supervision, Validation. LC: Conceptualization, Formal analysis, Supervision. LS: Conceptualization, Methodology. AS: Software, Validation. MP: Formal analysis, Data curation. ATR: Writing—review & editing, Supervision. MVE: Supervision, Validation, Visualization. All authors read and approved the submitted version.
Conflicts of interest
The authors declare that there are no conflicts of interest.
Ethical approval
This is a retrospective study spanning more than 40 years, based on data collected and archived at multiple centers; according to local regulation and to the best of our knowledge, specific ethical committee approval was not required.
Consent to participate
This study is retrospective and based on anonymized archived data collection over more than 40 years. At the time of data collection, patients had provided consent for clinical evaluation. Given the historical nature of the dataset, obtaining additional informed consent for the present analysis was not feasible and was therefore waived.
Consent to publication
Not applicable.
Availability of data and materials
The datasets generated and/or analyzed during the current study are not publicly available due to privacy and ethical restrictions, but are available from the corresponding author upon reasonable request and with permission of the participating institutions.
Open Exploration maintains a neutral stance on jurisdictional claims in published institutional affiliations and maps. All opinions expressed in this article are the personal views of the author(s) and do not represent the stance of the editorial team or the publisher.
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