From:  Biological activities of Punica granatum L. and the emerging role of metabolomics in enhancing its therapeutic potential: A narrative review

 Level of evidence of various studies of Punica granatum L.

Evidence levelKey findingsStrength of evidence
Traditional useCardiovascular and gastrointestinal benefitsHistorical/Ethnomedicinal
In vitro studiesAntioxidant, anti-inflammatory, antiproliferative effectsMechanistic
In vivo studiesHepatoprotective, cardioprotective, neuroprotective effectsModerate
Clinical studiesImprovements in blood pressure, lipid profile, glycemic markersStrongest available but still limited for some outcomes