From:  Production, properties and quality improvements of gluten-free bread from underutilised cereals and legumes

 Various health implications of GFB consumption.

Health impactBrief overviewMechanism/NotesImplications for GFB formulationReference
Nutritional deficiencies/Bone health riskGFB is often low in fiber, iron, calcium, and BvitaminsReliance on refined starches and lack of fortificationUse nutrient-dense flours, seeds, or fortification to balance diet[66]
Weight managementMixed effects; GFB may increase or decrease weightHigher caloric density of some GF breads; improved absorption in treated celiac casesOptimize energy content, fiber, and satiety-promoting ingredients[67]
Gastrointestinal comfortCan alleviate bloating, pain, and irregular bowel movementsGluten removal reduces inflammatory response in sensitive individualsConsider prebiotics, soluble fibers, or hydrocolloids to improve gut tolerance[68]
Glycemic response/DiabetesGFB can have a higher GI, affecting blood sugarRapid starch digestion due to refined flours; low fiber contentIncorporate whole grains, resistant starches, or viscous fibers to reduce GI[50]
Non-celiac gluten sensitivityMay relieve symptoms in some individualsSymptom reduction may be linked to FODMAP reduction rather than gluten aloneDesign GFB with low-FODMAP ingredients; monitor individual tolerance[69]

FODMAP: Fermentable Oligo-, Di-, Mono-saccharides, And Polyols; GFB: gluten-free bread; GI: glycemic index.