Exploration of Foods and Foodomics

Table 1. Summary of reviewed articles on dietary acid load, alkaline interventions, and metabolic health.

Ref.	Article type	Main focus	Population	Key findings
[20]	Narrative review	Chronic sub-clinical systemic metabolic acidosis	General adult	Mechanisms and clinical implications; diet’s role in acid load
[43]	Article commentary	Acid-forming properties of foods; PRAL/NEAP models	General population	Critiques current models; highlights the role of unaccounted dietary components
[29]	Systematic review	Bioavailability and metabolic role of magnesium supplements	General adult	Shows that magnesium forms with higher bioavailability (e.g., citrate) improve metabolic function and support physiological pH balance; highlights relevance of mineral supplementation for acid-base homeostasis
[21]	Review	Ketogenic diet in kidney disease management	Adults with CKD	Reno-protective potential; need for long-term studies
[46]	Case report	Ketone salts and metabolic alkalosis	Adult with MTPD	Reports metabolic alkalosis after ketone salts; clinical caution advised
[47]	Review	Recurrent calcium kidney stones; diet	Adults with nephrolithiasis	Dietary tailoring for stone prevention
[48]	Review	Diet and kidney stone disease	General adult	Acid load reduction lowers stone risk

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PRAL: potential renal acid load; NEAP: net endogenous acid production; CKD: chronic kidney disease; MTPD: mitochondrial trifunctional protein deficiency.

Declarations

Author contributions

MD: Conceptualization, Methodology, Investigation, Data curation, Writing—original draft, Writing—review & editing. GC: Conceptualization, Resources, Writing—review & editing, Supervision. LR: Conceptualization, Data curation, Writing—original draft, Resources, Writing—review & editing, Supervision, Project administration. All authors read and approved the submitted version.

Conflicts of interest

Luca Rastrelli, who is the Associate Editor of Exploration of Foods and Foodomics, had no involvement in the decision-making or the review process of this manuscript. The other authors declare no conflicts of interest.

Ethical approval

Not applicable.

Consent to participate

Not applicable.

Consent to publication

Not applicable.

Availability of data and materials

Not applicable.

Funding

Not applicable.

Copyright

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Open Exploration maintains a neutral stance on jurisdictional claims in published institutional affiliations and maps. All opinions expressed in this article are the personal views of the author(s) and do not represent the stance of the editorial team or the publisher.

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23.

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29.

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30.

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32.

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34.

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47.

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52.

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53.

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54.

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55.

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