Exploration of Asthma & Allergy

Table 2. Reported long-term outcomes in EGIDs.

EGID subtype	Long-term complications	Relapse risk	Impact on quality of life
Eosinophilic esophagitis (EoE)	Fibrostenosis and strictures in 30–40% of untreated patients; food impaction risk	High relapse is common after treatment withdrawal	Dysphagia, dietary restrictions, impaired social functioning
Eosinophilic gastritis	Gastric wall thickening, protein-losing enteropathy (rare)	50% recurrence after corticosteroid tapering	Chronic abdominal pain, nausea, nutritional compromise
Eosinophilic enteritis	Malabsorption, anemia, and occasional strictures	Frequent relapse, especially after drug cessation	Fatigue, weight loss, reduced work capacity
Eosinophilic colitis	Chronic diarrhea, occasional bleeding; less risk of strictures	Relapsing-remitting course in many patients	Impact on daily activities, anxiety related to chronic symptoms

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EGIDs: eosinophilic gastrointestinal disorders.

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Declarations

Author contributions

NN: Investigation, Writing—original draft. RD: Conceptualization, Investigation, Writing—review & editing. LM: Writing—review & editing. RY: Writing—review & editing. PD: Writing—review & editing. All authors read and approved the submitted version.

Conflicts of interest

The authors declare that they have no conflicts of interest.

Ethical approval

Ethical review was waived by the local ethics committee since this study was a secondary analysis of published anonymized data and a retrospective analysis of anonymized histopathology slides available in the departmental records.

Consent to participate

Informed consent to participate was obtained from relevant participants.

Consent to publication

Not applicable.

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Relevant data may be available from the corresponding author upon reasonable request.

Funding

Not applicable.

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