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References
Karavaizoglu C, Suleyman A, Yavuz Alıc R, Dolu KO, Yucel E, Demirkale ZH, et al. Drug Allergy in Children: Adverse Reactions after Skin Testing.Int Arch Allergy Immunol. 2024;185:56–62. [DOI] [PubMed]
Kidon M, Blanca-Lopez N, Gomes E, Terreehorst I, Tanno L, Ponvert C, et al. EAACI/ENDA Position Paper: Diagnosis and management of hypersensitivity reactions to non-steroidal anti-inflammatory drugs (NSAIDs) in children and adolescents.Pediatr Allergy Immunol. 2018;29:469–80. [DOI] [PubMed]
Sánchez-Borges M, Kidon MI. Reactions to Nonsteroidal Anti-Inflammatory Drugs in Children.J Allergy Clin Immunol Pract. 2018;6:1236–7. [DOI] [PubMed]
Blanca-Lopez N, Perez-Alzate D, Canto G, Blanca M. Practical approach to the treatment of NSAID hypersensitivity.Expert Rev Clin Immunol. 2017;13:1017–27. [DOI] [PubMed]
Pérez-Alzate D, Blanca-Lopez N, Cornejo JA, Somoza ML, Ruano FJ, Haroun E, et al. Comparison of NSAID Hypersensitivity between Children and Adolescents.J Clin Immunol. 2017;139:AB35.
Simons FE, Ebisawa M, Sanchez-Borges M, Thong BY, Worm M, Tanno LK, et al. 2015 update of the evidence base: World Allergy Organization anaphylaxis guidelines.World Allergy Organ J. 2015;8:32. [DOI] [PubMed] [PMC]
Cavkaytar O, du Toit G, Caimmi D. Characteristics of NSAID-induced hypersensitivity reactions in childhood.Pediatr Allergy Immunol. 2019;30:25–35. [DOI] [PubMed]
Thong BY. Nonsteroidal anti-inflammatory drug hypersensitivity in the Asia-Pacific.Asia Pac Allergy. 2018;8:e38. [DOI] [PubMed] [PMC]
Sipahi Cimen S, Yucel E, Ozceker D, Suleyman A, Hizli Demirkale Z, Sayili U, et al. Behind the scene: Paracetamol hypersensitivity in children.Pediatr Allergy Immunol. 2020;32:177–85. [DOI]
Cousin M, Chiriac A, Molinari N, Demoly P, Caimmi D. Phenotypical characterization of children with hypersensitivity reactions to NSAIDs.Pediatr Allergy Immunol. 2016;27:743–8. [DOI]
Gomes ER, Brockow K, Kuyucu S, Saretta F, Mori F, Blanca-Lopez N, et al.; ENDA/EAACI Drug Allergy Interest Group. Drug hypersensitivity in children: report from the pediatric task force of the EAACI Drug Allergy Interest Group.Allergy. 2016;71:149–61. [DOI] [PubMed]
Dogan S, Ertugrul A, Ozer M, Severcan EU, Sirin S, Ozmen S. Assessment of pediatric patients with suspected nonsteroidal anti-inflammatory drug hypersensitivity.Allergy Asthma Proc. 2024;45:e81–6. [DOI] [PubMed]
Podlecka D, Socha-Banasiak A, Jerzynska J, Nodzykowska J, Brzozowska A. Practical Approach to Hypersensitivity to Nonsteroidal Anti-Inflammatory Drugs (NSAIDs) in Children.Pharmaceuticals (Basel). 2023;16:1237. [DOI] [PubMed] [PMC]
Yilmaz Topal O, Kulhas Celik I, Turgay Yagmur I, Toyran M, Civelek E, Karaatmaca B, et al. Results of NSAID provocation tests and difficulties in the classification of children with nonsteroidal anti-inflammatory drug hypersensitivity.Ann Allergy Asthma Immunol. 2020;125:202–7. [DOI] [PubMed]
Li L, Bensko J, Buchheit K, Saff RR, Laidlaw TM. Safety, Outcomes, and Recommendations for Two-Step Outpatient Nonsteroidal Anti-Inflammatory Drug Challenges.J Allergy Clin Immunol Pract. 2022;10:1286–92.e2. [DOI] [PubMed] [PMC]
Aytekin Güvenir F, Turgay Yağmur İ, Dibek Mısırlıoğlu E. Alternative Drug Safety in Children with Nonsteroidal Anti-Inflammatory Drug Hypersensitivity.Int Arch Allergy Immunol. 2024;185:921–7. [DOI] [PubMed]
Mori F, Atanaskovic-Markovic M, Blanca-Lopez N, Gomes E, Gaeta F, Sarti L, et al. A Multicenter Retrospective Study on Hypersensitivity Reactions to Nonsteroidal Anti-Inflammatory Drugs (NSAIDs) in Children: A Report from the European Network on Drug Allergy (ENDA) Group.J Allergy Clin Immunol Pract. 2020;8:1022–31.e1. [DOI] [PubMed]
Guvenir H, Dibek Misirlioglu E, Vezir E, Toyran M, Ginis T, Civelek E, et al. Nonsteroidal anti-inflammatory drug hypersensitivity among children.Allergy Asthma Proc. 2015;36:386–93. [DOI] [PubMed]
Hadley A, Slaven JE, Krupp NL, Kloepfer KM. Nonsteroidal anti-inflammatory drug hypersensitivity in a pediatric severe asthmatic population.Pediatr Pulmonol. 2023;58:2983–6. [DOI] [PubMed] [PMC]
Metbulut AP, Haci İA, Can D, Bekis Bozkurt H, Cavkaytar Ö, Arga M, et al. Evaluation of drug-related anaphylaxis in children: multi-center study.Eur J Pediatr. 2025;184:230. [DOI] [PubMed]
Baxter L, Cobo MM, Bhatt A, Slater R, Sanni O, Shinde N. The association between ibuprofen administration in children and the risk of developing or exacerbating asthma: a systematic review and meta-analysis.BMC Pulm Med. 2024;24:412. [DOI] [PubMed] [PMC]
González Moreno A, Tejedor Alonso MÁ, Brandoni Petroni M, Pérez Fernández E, Rosado Ingelmo A. Natural history of cross intolerance to non-steroidal anti-inflammatory drugs in the pediatric population.Pediatr Allergy Immunol. 2025;36:e70057. [DOI] [PubMed]
Tekcan D, Guler T, Comert M, Artac H, Kulhas Celik I. Comparison of negative predictive values of single- and two-day provocation tests with suspected nonsteroidal anti-inflammatory drug and paracetamol allergy in children.Allergy Asthma Proc. 2025;46:e166–71. [DOI] [PubMed] [PMC]
Uluc NN, Uluc NN, Iskender N, Ozanli I, Akin TY, Varli YZ, et al. Tolerance Evaluation of Nonsteroidal Anti-Inflammatory Drug Hypersensitivity in Children: Is Age the Crucial Factor?Int Arch Allergy Immunol. 2025;186:1155–65. [DOI] [PubMed]
Arikoglu T, Tokmeci N, Demirhan A, Kont Ozhan A, Yalaki AI, Akbey V, et al. Evaluation of different protocols for classification of pediatric hypersensitivity reactions to nonsteroidal anti-inflammatory drugs: Children with underlying allergic disease should be a separate subgroup.Allergy Asthma Proc. 2024;45:14–23. [DOI] [PubMed]
Stehlin F, Prosty C, Mulé A, Al-Otaibi I, Colli LD, Gaffar J, et al. Guiding Drug Provocation Testing for Ibuprofen Hypersensitivity in a Pediatric Population: Development of the I3A Risk-Stratification Tool.J Allergy Clin Immunol Pract. 2025;13:583–93.e3. [DOI] [PubMed]
Amo G, García-Menaya JM, Martí M, Gómez-Tabales J, Cornejo-García JA, Blanca-López N, et al. Genetic and serum biomarkers of NSAID hypersensitivity reactions.Front Pharmacol. 2025;16:1502755. [DOI] [PubMed] [PMC]
Humphrey-Murto S, Wood TJ, Gonsalves C, Mascioli K, Varpio L. The Delphi Method.Acad Med. 2020;95:168. [DOI] [PubMed]
Hoffmann-Eßer W, Siering U, Neugebauer EAM, Brockhaus AC, McGauran N, Eikermann M. Guideline appraisal with AGREE II: online survey of the potential influence of AGREE II items on overall assessment of guideline quality and recommendation for use.BMC Health Serv Res. 2018;18:143. [DOI] [PubMed] [PMC]
Doña I, Barrionuevo E, Salas M, Cornejo-García JA, Perkins JR, Bogas G, et al. Natural evolution in patients with nonsteroidal anti-inflammatory drug-induced urticaria/angioedema.Allergy. 2017;72:1346–55. [DOI] [PubMed]
